Antifungal Activity of PvD1 Defensin Involves Plasma Membrane Permeabilization, Inhibition of Medium Acidification, and Induction of ROS in Fungi Cells

2010 ◽  
Vol 62 (4) ◽  
pp. 1209-1217 ◽  
Author(s):  
Erica O. Mello ◽  
Suzanna F. F. Ribeiro ◽  
André O. Carvalho ◽  
Izabela S. Santos ◽  
Maura Da Cunha ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Antifungal Activity ◽  
Membrane Permeabilization ◽  
Medium Acidification ◽  
Plasma Membrane Permeabilization

Antifungal activity of tobacco osmotin has specificity and involves plasma membrane permeabilization

Plant Science ◽  
1996 ◽  
Vol 118 (1) ◽  
pp. 11-23 ◽  
Author(s):  
Laura R. Abad ◽  
Matilde Paino D'Urzo ◽  
Dong Liu ◽  
Meena L. Narasimhan ◽  
Moshe Reuveni ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Antifungal Activity ◽  
Membrane Permeabilization ◽  
Plasma Membrane Permeabilization

Platelet Density-Dependent Partition of Platelet- von Willebrand Factor Between Alpha Granule and Non-Alpha Granule Pools

1987 ◽  
Vol 58 (03) ◽  
pp. 911-914 ◽  
Author(s):  
R I Parker ◽  
Brenda C Shafer ◽  
H R Gralnick
Keyword(s):  
Plasma Membrane ◽  
Von Willebrand Factor ◽  
Plasma Proteins ◽  
Buoyant Density ◽  
Membrane Permeabilization ◽  
Density Profiles ◽  
Density Dependent ◽  
Plasma Membrane Permeabilization ◽  
Von Willebrand ◽  
Willebrand Factor

SummaryIn this study, we demonstrate that platelets contain a small hut significant amount of platelet-von Willebrand factor(vWf) not associated with α-granules. When platelets free of plasma proteins are exposed to micromolar concentrations ofdigitonin, plasma membrane permeabilization occurs without disruption of platelet granules. Employing this technique, wehave found that upon exposure of a total platelet population to 8 μM digitonin, 5% of total platelet-vWf is released into the supernatant; this occurs without release of (β-TG from α-granules. When platelets of discrete buoyant density profiles are tested, this extragranular platelet-vWf increased with decreasing platelet density. These findings suggest that a redistribution of platelet-vWf from α-granule to non-granule sites occurs coincident with a decrease inplatelet buoyant density.

Sign in / Sign up

Export Citation Format

Share Document