Diffuse axonal injury: its role in diffuse brain injury and its significance for severe disability and vegetative state

2000 ◽  
Vol 9 (6) ◽  
pp. 367-375 ◽  
Author(s):  
Gerhard Franz Walter
Author(s):  
Ronald J. Fijalkowski ◽  
Brian D. Stemper ◽  
Frank A. Pintar ◽  
Narayan Yoganandan ◽  
Thomas A. Gennarelli

Diffuse brain injury (DBI) severity can be clinically diagnosed as concussion or diffuse axonal injury (DAI). Concussion the least severe DBI, is associated with neurological deficit limited to disorientation and unconsciousness lasting minutes to hours [1–4]. In contrast, DAI, a severe injury, commonly results in death or permanent vegetation [1]. It is generally accepted that injury severity is modulated by increased mechanical measures such as rotational acceleration and velocity [5–11].


2018 ◽  
Vol 20 (4) ◽  
pp. 436-438
Author(s):  
Leonardo Abdala Giacomini ◽  
Miguel San Martin Sepulveda ◽  
Rodrigo Alves de C. Cavalcante ◽  
Helder Tedeschi

The diffuse axonal injury (DAI) is one of the main forms of traumatic brain injury, characterized by involvement of the axonal fibres of the white matter of the brain.The mechanism of such injury is the sum of forces of acceleration, deceleration and rotation, mainly in brain structures close to the middle line, including the dorsolateral superior region of the pons and midbrain, splenium of the corpus callosum, parasagittal white matter, and occasionally the internal capsule. Because of the importance of the structures commonly involved and its high incidence, close to 50 % of cases of severe brain trauma, the DAI is a major cause of cognitive impairment as well as the persistent vegetative state related to trauma. However, the occurrence of motor deficit outside of this area is uncommon in literature, and it is obviously dependant on the anatomical region involved6. The objective of this paper is to present a case of hemiplegia secondary to DAI.


1984 ◽  
Vol 24 (12) ◽  
pp. 946-953
Author(s):  
Akihito SAITO ◽  
Nobumasa KUWANA ◽  
Yasuhiko MOCHIMATSU ◽  
Hideyo FUJINO ◽  
Kazuhiko TOKORO

2009 ◽  
Vol 68 (3) ◽  
pp. 241-249 ◽  
Author(s):  
Melissa J. McGinn ◽  
Brian J. Kelley ◽  
Linnet Akinyi ◽  
Monika W. Oli ◽  
Ming Cheng Liu ◽  
...  

1998 ◽  
Vol 7 (7) ◽  
pp. 433-439 ◽  
Author(s):  
Yoshio TAGUCHI ◽  
Yasuji MIYAKITA ◽  
Motoshi MATSUZAWA ◽  
Yohtaro SAKAKIBARA ◽  
Taro TAKAHARA ◽  
...  

1995 ◽  
Vol 11 (7) ◽  
pp. 400-405 ◽  
Author(s):  
J. Bosch Blancafort ◽  
M. Olesti Marco ◽  
J. M. Poch Puig ◽  
E. Rubio Garc�a ◽  
P. Nogu�s Bara ◽  
...  

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