Background:
One of the main sources of ROS in stress conditions is the mitochondria. Excessive
generation of ROS leads to oxidation of thiol groups of proteins, peroxidation of membrane
lipids and swelling of the mitochondria. In this regard, there is a need to search for preparationsadaptogens
that increase the body's resistance to stress factors. Perhaps, antioxidants can serve as such
adaptogens. This work aims at studying the effect of antioxidant; the potassium anphen in a wide range
of concentrations on the functional state of 6 day etiolated pea seedlings mitochondria (Pisum sativum
L).
Methods:
The functional state of mitochondria was studied per rates of mitochondria respiration, by the
level of lipid peroxidation and study of fatty acid composition of mitochondrial membranes by chromatography
technique.
Results:
Potassium anphen in concentrations of 10-5 - 10-8 M and 10-13-10-16 prevented the activation of
LPO in the mitochondrial membranes of pea seedlings, increased the oxidation rates of NAD-dependent
substrates and succinate in the respiratory chain of mitochondria that probably pointed to the anti-stress
properties of the drug. Indeed, the treatment of pea seeds with the preparation in concentrations of 10-13
M prevented the inhibition of growth of seedlings in conditions of water deficiency.
Conclusion:
It is assumed that the dose dependence of the biological effects of potassium anphen and
the manifestation of these effects in ultra-low concentrations are due to its ability in water solutions to
form a hydrate containing molecular ensembles (structures).
Correction to: Correlative Inhibition Between Branches in Two-Branched Pea Seedlings is Cultivar-Dependent
