The impact of initial hematocrit values after birth on peri-/intraventricular hemorrhage in extremely low birth weight neonates

2021 ◽  
Author(s):  
Belma Saygili Karagol ◽  
Erhan Calisici ◽  
Cengiz Zeybek ◽  
Bulent Unay ◽  
Selcen Yuksel
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Intraventricular Hemorrhage ◽  
Extremely Low Birth Weight ◽  
The Impact

scholarly journals Amikacin or Vancomycin Exposure Alters the Postnatal Serum Creatinine Dynamics in Extreme Low Birth Weight Neonates

2021 ◽  
Vol 18 (2) ◽  
pp. 662
Author(s):  
Tamara van Donge ◽  
Anne Smits ◽  
John van den Anker ◽  
Karel Allegaert
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Serum Creatinine ◽  
Potential Effect ◽  
Extremely Low Birth Weight ◽  
Treatment Modalities ◽  
Antibiotic Exposure ◽  
Sensitive Tool ◽  
Elbw Neonates ◽  
The Impact

Background: Disentangling renal adverse drug reactions from confounders remains a major challenge to assess causality and severity in neonates, with additional limitations related to the available tools (modified Kidney Disease Improving Global Outcome, or Division of Microbiology and Infectious Diseases pediatric toxicity table). Vancomycin and amikacin are nephrotoxic while still often prescribed in neonates. We selected these compounds to assess their impact on creatinine dynamics as a sensitive tool to detect a renal impairment signal. Methods: A recently developed dynamical model that characterized serum creatinine concentrations of 217 extremely low birth weight (<1000 g, ELBW) neonates (4036 observations) was enhanced with data on vancomycin and/or amikacin exposure to identify a potential effect of antibiotic exposure by nonlinear mixed-effects modelling. Results: Seventy-seven percent of ELBW patients were exposed to either vancomycin or amikacin. Antibiotic exposure resulted in a modest increase in serum creatinine and a transient decrease in creatinine clearance. The serum creatinine increase was dependent on gestational age, illustrated by a decrease with 56% in difference in serum creatinine between a 24 or 32-week old neonate, when exposed in the 3rd week after birth. Conclusions: A previously described model was used to explore and quantify the impact of amikacin or vancomycin exposure on creatinine dynamics. Such tools serve to explore minor changes, or compare minor differences between treatment modalities.

The Impact of Fluid Therapy Strategies on Nonoliguric Hyperkalemia in Extremely Low Birth Weight Infants

2014 ◽  
Vol 21 (1) ◽  
pp. 28
Author(s):  
Min Young Kim ◽  
Eun Jae Chang ◽  
Young Hye Kim ◽  
Woo Jung Jang ◽  
Hye Jung Cho ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Fluid Therapy ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Therapy Strategies ◽  
The Impact

scholarly journals Hypernatremia and grade III/IV intraventricular hemorrhage among extremely low birth weight infants

2010 ◽  
Vol 31 (3) ◽  
pp. 193-198 ◽  
Author(s):  
W-H Lim ◽  
R Lien ◽  
M-C Chiang ◽  
R-H Fu ◽  
J-J Lin ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Intraventricular Hemorrhage ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Grade Iii

scholarly journals Morbidity in extreme low birth weight newborns hospitalized in a high risk public maternity

2017 ◽  
Vol 17 (1) ◽  
pp. 139-147 ◽  
Author(s):  
Derijulie Siqueira Sousa ◽  
Airton Salviano Sousa Júnior ◽  
Arielly Duarte Rabelo Santos ◽  
Enaldo Vieira Melo ◽  
Sônia Oliveira Lima ◽  
...  
Keyword(s):  
Birth Weight ◽  
High Risk ◽  
Low Birth Weight ◽  
Intraventricular Hemorrhage ◽  
Ductus Arteriosus ◽  
Extremely Low Birth Weight ◽  
Average Weight ◽  
Newborn Intensive Care Unit ◽  
Kaplan Meier ◽  
Persistent Arterial Duct

Abstract Objectives: to determine the prevalence of the most common morbidities in extremely low birth weight (ELBW) infants hospitalized in a newborn intensive care unit (NICU) and to evaluate the influence of these morbidities through the length of in-hospital stay. Methods: observational, longitudinal, prospective and analytical study in a high risk reference maternity NICU from Sergipe, realized with 158 ELBW infants admitted between March 2014 and April 2015. The analysis of the hospitalization time was realized through the Kaplan-Meier method. Results: the average weight of premature was 785,2g ± 138,2g. The gestational age vary from 22 to 35 weeks and the average was 26,8 weeks. Of those admitted at NICU, sixty three (39,9%) were discharged and 95 (60,1%) died. The time of hospitalization was influenced for morbidities as: patent ductus arteriosus (PDA), intraventricular hemorrhage and sepsis. Acute respiratory distress syndrome was the most common complication (157 - 99,4%). The incidence of persistent arterial duct, intraventricular hemorrhage, sepsis, hypothermia, hypoglycemia and retinopathy of prematurity was 39,2%, 17,1%, 32,3%,50,3%, 52,3% e 16,6% respectively. Conclusions: the morbidities from respiratory tract, cardiac, neurological and infectious were the most prevalent, whilst PDA, intraventricular hemorrhage and sepsis were the morbidities that significantly influenced the time of hospitalization.

Grades I-II intraventricular hemorrhage in extremely low birth weight infants: Effects on neurodevelopment

2006 ◽  
Vol 149 (2) ◽  
pp. 169-173 ◽  
Author(s):  
Kousiki Patra ◽  
Deanne Wilson-Costello ◽  
H. Gerry Taylor ◽  
Nori Mercuri-Minich ◽  
Maureen Hack
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Intraventricular Hemorrhage ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants

The impact of surgery on infants born at extremely low birth weight

2003 ◽  
Vol 38 (6) ◽  
pp. 924-927 ◽  
Author(s):  
Jonathan N Limpert ◽  
Patricia A Limpert ◽  
Thomas R Weber ◽  
Richard J Bower ◽  
Jennifer A Trimble ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Extremely Low Birth Weight ◽  
The Impact
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