The efficacy of “Abound™,” a nutritional supplement containing l-glutamine, l-arginine, citric acid, and calcium HMB, for skin disorders that developed as adverse drug reactions to anti-EGFR antibody preparation administration: pilot study

2015 ◽  
Vol 31 (5) ◽  
pp. 1055-1057 ◽  
Author(s):  
Nobuhisa Matsuhashi ◽  
Takao Takahashi ◽  
Toshiyuki Tanahashi ◽  
Satoshi Matsui ◽  
Yoshiyuki Sasaki ◽  
...  
Keyword(s):  
Citric Acid ◽  
Pilot Study ◽  
Adverse Drug Reactions ◽  
Nutritional Supplement ◽  
Skin Disorders ◽  
Drug Reactions ◽  
Antibody Preparation ◽  
Egfr Antibody

Older Adults' Response to Analgesic Adverse Drug Reactions: A Pilot Study

2018 ◽  
Vol 19 (4) ◽  
pp. 333-339 ◽  
Author(s):  
Deborah Dillon McDonald ◽  
Sarah Coughlin ◽  
Candy Jin
Keyword(s):  
Older Adults ◽  
Pilot Study ◽  
Adverse Drug Reactions ◽  
Drug Reactions

scholarly journals Patients views and experiences in online reporting adverse drug reactions: findings of a national pilot study in Japan

2015 ◽  
pp. 173 ◽  
Author(s):  
Michiko Yamamoto ◽  
Kiyoshi Kubota ◽  
Mitsuhiro Okazaki ◽  
Akira Dobashi ◽  
Masayuki Hashiguchi ◽  
...  
Keyword(s):  
Pilot Study ◽  
Adverse Drug Reactions ◽  
Drug Reactions

The final report of post-marketing surveillance for cetuximab in colorectal cancer in Japan.

2011 ◽  
Vol 29 (4_suppl) ◽  
pp. 590-590 ◽  
Author(s):  
K. Yamaguchi ◽  
T. Satoh ◽  
T. Watanabe ◽  
M. Ishiguro ◽  
K. Maruyama ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Adverse Drug Reactions ◽  
Infusion Reaction ◽  
Gastrointestinal Disorders ◽  
Final Report ◽  
Skin Disorders ◽  
Drug Reactions ◽  
Post Marketing Surveillance ◽  
Number Of Patients ◽  
Post Marketing

590 Background: Cetuximab (ERBITUX) was approved in Jul 2008 in Japan with indication for EGFR-positive and unresectable metastatic or refractory colorectal cancer. Post-marketing surveillance is required by Japanese Health Authority to collect, obtain, verify or validate information on the safety, efficacy and quality of medicines. We conducted this surveillance in all patients treated with cetuximab to access in practical use since clinical data on Japanese patients are limited. Methods: The target number of patients was 1,800. Following adverse drug reactions were investigated: infusion reaction, skin disorders, interstitial lung diseases, electrolyte abnormalities (including hypomagnesemia), heart toxicities, gastrointestinal disorders, thrombosis/embolism, delayed wound healing, and eye disorders. Results: Between Sep 2008 until Jan 2010, 2,126 pts registered, 2,006 pts were evaluable for safety (safety population), 1,687 pts for efficacy (efficacy population). Of the 2,006 pts, 1,975 pts (98.5%) were EGFR-positive. Patients characteristics: male/female; 1,234/772 (61.5%/38.5%), median age; 64 (range 18-87), site of primary tumor; colon/rectal/others (multiple selection); 1,235/775/3 (61.6%/38.6%/0.2%), PS0/PS1; 1,370/630 (68.3%/31.4%), combination chemotherapy; cetuximab monotherapy/CPT-11/FOLFIRI: 460/1,255/256 (22.9%/62.56%/12.8%). Of the 2,006 pts, 133 pts (6.6%) and 1,869 pts (93.2%) were treated in second-line and in third-line or later treatment, respectively. The adverse drug reactions incidence was 89.9%. Incidence of skin disorders, gastrointestinal disorders, electrolyte abnormality including hypomagnesaemia, and infusion reaction were 83.7%, 23.1%, 11.5%, and 5.7%, respectively. Efficacy result: Of the 1,687 pts, 658 pts (39.0%) were evaluated to be effective. Of the 658 pts, 614 pts (93.3%) experienced skin adverse reactions. Conclusions: This post-marketing surveillance confirms the safety and efficacy of cetuximab in the Japanese population treated in clinical practice. The outcome of this surveillance with Japanese 2,006 pts would be useful for clinical use of cetuximab. [Table: see text]

Pilot Study to Assess Subjective and Objective Reporting of Potential Adverse Drug Reactions in Older Versus Younger HIV-Infected Patients Using Antiretroviral Therapy

2012 ◽  
Vol 23 (5) ◽  
pp. 397-408
Author(s):  
Amy A. Hirsch ◽  
Anita Compan ◽  
Renée H. Lawrence ◽  
Janet M. Briggs ◽  
Gopala K. Yadavalli ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Pilot Study ◽  
Adverse Drug Reactions ◽  
Drug Reactions

Community pharmacists’ views on adverse drug reactions reporting in Malaysia: a pilot study

2010 ◽  
Vol 32 (3) ◽  
pp. 339-342 ◽  
Author(s):  
Kang-Nee Ting ◽  
Dane Michael Stratton-Powell ◽  
Claire Anderson
Keyword(s):  
Pilot Study ◽  
Adverse Drug Reactions ◽  
Community Pharmacists ◽  
Drug Reactions

scholarly journals A pilot study to evaluate a community pharmacy–based monitoring system to identify adverse drug reactions associated with paediatric medicines use

2010 ◽  
Vol 66 (6) ◽  
pp. 627-632 ◽  
Author(s):  
Mansour Tobaiqy ◽  
Derek Stewart ◽  
Peter J. Helms ◽  
Christine Bond ◽  
Amanda Jane Lee ◽  
...  
Keyword(s):  
Pilot Study ◽  
Community Pharmacy ◽  
Monitoring System ◽  
Adverse Drug Reactions ◽  
Drug Reactions ◽  
Medicines Use ◽  
Paediatric Medicines

scholarly journals Adverse drug reactions in internal medicine units at a university hospital: A descriptive pilot study

1969 ◽  
Vol 41 (1) ◽  
pp. 45-51
Author(s):  
Luis Carlos López ◽  
Marcela Botero ◽  
Jaime Pino ◽  
Jorge Hernán Ramírez ◽  
Mauricio Palacios
Keyword(s):  
Internal Medicine ◽  
Pilot Study ◽  
Adverse Drug Reactions ◽  
University Hospital ◽  
Drug Reactions

Adverse Drug Reactions to Off-label Drugs on a Paediatric Ward: an Italian Prospective Pilot Study

2002 ◽  
Vol 5 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Piero Impicciatore ◽  
Angelika Mohn ◽  
F Chiarelli ◽  
Chiara Pandolfini ◽  
Maurizio Bonati
Keyword(s):  
Pilot Study ◽  
Adverse Drug Reactions ◽  
Drug Reactions ◽  
Paediatric Ward ◽  
Off Label ◽  
Prospective Pilot Study

scholarly journals A prospective observational pilot study of adverse drug reactions contributing to hospitalization in a cohort of middle-aged adults aged 45–64 years

2020 ◽  
Vol 36 (3) ◽  
pp. 123-130
Author(s):  
T. Smeaton ◽  
P. McElwaine ◽  
J. Cullen ◽  
M. J. Santos-Martinez ◽  
E. Deasy ◽  
...  
Keyword(s):  
Pilot Study ◽  
Adverse Drug Reactions ◽  
Drug Reactions ◽  
Middle Aged ◽  
Middle Aged Adults
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