Surgical management of splenic flexure colon cancer: a retrospective propensity-matched study comparing open and minimally invasive approaches using the national cancer database

2021 ◽  
Author(s):  
Michael L. Horsey ◽  
Andrew D. Sparks ◽  
Debra Lai ◽  
Aalap Herur-Raman ◽  
Matthew Ng ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Minimally Invasive ◽  
Surgical Management ◽  
Splenic Flexure ◽  
National Cancer Database ◽  
Matched Study

A Tale of Two Colons and Two Cancers

Swiss Surgery ◽  
2003 ◽  
Vol 9 (1) ◽  
pp. 3-7 ◽  
Author(s):  
Gervaz ◽  
Bühler ◽  
Scheiwiller ◽  
Morel
Keyword(s):  
Colorectal Cancer ◽  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Splenic Flexure ◽  
Chromosomal Instability ◽  
Proximal Colon ◽  
Colorectal Carcinogenesis ◽  
Physiological Data ◽  
Central Hypothesis ◽  
Group Stratification

The central hypothesis explored in this paper is that colorectal cancer (CRC) is a heterogeneous disease. The initial clue to this heterogeneity was provided by genetic findings; however, embryological and physiological data had previously been gathered, showing that proximal (in relation to the splenic flexure) and distal parts of the colon represent distinct entities. Molecular biologists have identified two distinct pathways, microsatellite instability (MSI) and chromosomal instability (CIN), which are involved in CRC progression. In summary, there may be not one, but two colons and two types of colorectal carcinogenesis, with distinct clinical outcome. The implications for the clinicians are two-folds; 1) tumors originating from the proximal colon have a better prognosis due to a high percentage of MSI-positive lesions; and 2) location of the neoplasm in reference to the splenic flexure should be documented before group stratification in future trials of adjuvant chemotherapy in patients with stage II and III colon cancer.

Minimally Invasive Versus Open Approach for Cystectomy: Trends in the Utilization and Demographic or Clinical Predictors Using the National Cancer Database

Urology ◽  
2017 ◽  
Vol 103 ◽  
pp. 99-105 ◽  
Author(s):  
Andrew G. Bachman ◽  
Alexander A. Parker ◽  
Marshall D. Shaw ◽  
Brian W. Cross ◽  
Kelly L. Stratton ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Open Approach ◽  
National Cancer Database ◽  
Clinical Predictors

Minimally Invasive Surgical Approaches to Colon Cancer

2018 ◽  
Vol 27 (2) ◽  
pp. 303-318 ◽  
Author(s):  
Jean F. Salem ◽  
Sriharsha Gummadi ◽  
John H. Marks
Keyword(s):  
Colon Cancer ◽  
Minimally Invasive ◽  
Surgical Approaches ◽  
Minimally Invasive Surgical

Classifications of acute pancreatitis: to Atlanta and beyond

Open Medicine ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. 543-549
Author(s):  
Anna Pallisera ◽  
Farah Adel ◽  
Jose Ramia
Keyword(s):  
Acute Pancreatitis ◽  
Minimally Invasive ◽  
Surgical Management ◽  
Historical Review ◽  
Diagnostic Methods ◽  
Local Complications ◽  
Made In

AbstractUntil Atlanta Classification (AC) made in 1992, there was not any classification of acute pancreatitis (AP). Last twenty years AC let us compare results and papers. But the increasing understanding of the pathophysiology of AP, improvements in diagnostic methods and the development of minimally invasive tools for radiological, endoscopic and surgical management of local complications, several authors have called for the AC to be reviewed. Last months, two new classifications of AP have been published. We made a historical review of AC, the two new classifications and a comparison between them.

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