Evaluation of fetal cardiac function in pregnancies with well-controlled gestational diabetes

2021 ◽  
Author(s):  
F. D’Ambrosi ◽  
G. Rossi ◽  
C. M. Soldavini ◽  
I. F. Carbone ◽  
G. E. Cetera ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Cardiac Function ◽  
Fetal Cardiac Function

scholarly journals Evaluation of fetal cardiac function in maternal gestational diabetes mellitus by speckle tracking echocardiography

2021 ◽  
Author(s):  
Peina Huang ◽  
Youbin Deng ◽  
Ling Feng ◽  
Yiping Gao ◽  
Xueqing Cheng ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Right Ventricle ◽  
Cardiac Function ◽  
Gestational Diabetes Mellitus ◽  
Right Ventricular ◽  
Speckle Tracking ◽  
Speckle Tracking Echocardiography ◽  
Fetal Cardiac Function ◽  
The Right

Abstract The aim of this study was to assess the cardiac function in fetuses of mothers with gestational diabetes mellitus (GDM) by using fetalHQ, a quantitative analysis software for the assessment of fetal cardiac function based on speckle tracking echocardiography. In this prospective cross-sectional study, 49 fetuses exposed to GDM and 50 normal fetuses were enrolled and fetal echocardiography were performed and analyzed. In the GDM group, left ventricular (24 ± 4 vs. 28 ± 4, p < 0.001) and right ventricular global longitudinal strain (23 ± 4 vs. 26 ± 4, p = 0.002) and right ventricular free wall strain (26 ± 6 vs. 29 ± 5, p = 0.006) were significantly lower compared with the control group, whereas there was no significant difference in global spherical index (1.2 ± 0.1 vs. 1.2 ± 0.1, p = 0.425). Additionally, 24-segment transverse fraction shortening of the right ventricle was more impaired than the left and the segments with reduced fraction shortening were mainly located in the mid and apical sections of the right ventricle, and mid section of the left ventricle. In conclusion, fetuses exposed to GDM may have cardiac dysfunction before the onset of cardiac morphologic abnormalities, and the right ventricle is more vulnerable than the left during fetal development.

The correlation of fetal cardiac function with gestational diabetes mellitus (GDM) and oxidative stress levels

2020 ◽  
Vol 48 (5) ◽  
pp. 471-476
Author(s):  
Phudit Jatavan ◽  
Thitikarn Lerthiranwong ◽  
Rattanaporn Sekararithi ◽  
Thidarat Jaiwongkam ◽  
Sirinart Kumfu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Cardiac Function ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Fetal Cardiac Function ◽  
Function Impairment ◽  
Stress Levels ◽  
High Level

AbstractBackgroundThe primary objective of this study was to compare the fetal cardiac performance index (Tei index) between the fetuses of gestational diabetes mellitus (GDM) mothers and non-GDM mothers; and the secondary objective was to compare various other parameters of fetal cardiac function as well as maternal oxidative stress levels between the groups of GDM and non-GDM mothers.MethodsA cross-sectional study was conducted on pregnant women at 24–28 weeks of gestation. All of the participants underwent 100 g, 3-h oral glucose tolerance test (OGTT) as a diagnostic test for GDM and were categorized as non-GDM and GDM group. All participants had fetal echocardiography performed for cardiac function, and then maternal blood samples were collected for biomarker measurements.ResultsA total of 80 pregnant women, including 43 in the GDM group and 37 in the non-GDM group, were included in the study. The maternal serum 8-isoprostane (8IsoP), tumor necrosis factor-α (TNF-α) and interleukin (IL)-10 levels were significantly higher in the GDM group than those in the non-GDM group (P: 0.028, P: 0.019 and P: 0.031, respectively). The fetal cardiac function parameters were not significantly different between the two groups. Regardless of the GDM status, the fetuses with high levels of oxidative stress (8Isop ≥1000 pg/mg protein) had a significantly higher rate of impaired shortening fraction (SF) of the left ventricle (P: 0.001).ConclusionGDM is significantly associated with an increase in the oxidative stress process, and a high level of oxidative stress was significantly associated with left ventricular (LV) function impairment. Though a correlation between GDM and fetal cardiac function impairment was not clearly demonstrated in this study, this study suggests that GDM patients with a high level of oxidative stress should be evaluated for fetal cardiac function.

Possibilities of applying speckle tracking echocardiography to assess fetal myocardial function. Part 1. Methods to assess fetal cardiac function

2019 ◽  
Author(s):  
S.I. Buryakova, M.V. Medvedev
Keyword(s):  
Cardiac Function ◽  
Speckle Tracking ◽  
Myocardial Function ◽  
Speckle Tracking Echocardiography ◽  
Myocardial Deformation ◽  
Prenatal Period ◽  
Fetal Cardiac Function ◽  
Deformation Properties

The article deals with the physiology of the heart and methods to assess fetal cardiac function. The leadingedge technique to assess the myocardial deformation properties by speckle tracking echocardiography in prenatal period is presented.

scholarly journals Anesthetic Techniques for Fetal Surgery

2013 ◽  
Vol 118 (4) ◽  
pp. 796-808 ◽  
Author(s):  
Pornswan Ngamprasertwong ◽  
Erik C. Michelfelder ◽  
Shahriar Arbabi ◽  
Yun Suk Choi ◽  
Christopher Statile ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cardiac Function ◽  
Fetal Surgery ◽  
Left Ventricular ◽  
High Dose ◽  
Anesthetic Techniques ◽  
Uterine Blood Flow ◽  
Fetal Cardiac Function ◽  
Significant Difference ◽  
Fetal Acidosis

Abstract Background: Use of high-dose inhalational anesthesia during open fetal surgery may induce maternal–fetal hemodynamic instability and fetal myocardial depression. The authors’ preliminary human retrospective study demonstrated less fetal bradycardia and left ventricular systolic dysfunction with lower dose desflurane supplemented with propofol and remifentanil IV anesthesia (SIVA). In this animal study, the authors compare maternal–fetal effects of high-dose desflurane anesthesia (HD-DES) and SIVA. Methods: Of 26 instrumented midgestational ewes, data from 11 animals exposed to both SIVA and HD-DES in random sequences and six animals exposed to HD-DES while maternal normotension was maintained were analyzed. Maternal electroencephalography was used to guide comparable depths of anesthesia in both techniques. Hemodynamic parameters, blood gas, and fetal cardiac function from echocardiography were recorded. Results: Compared with SIVA, HD-DES resulted in significant maternal hypotension (mean arterial pressure difference, 19.53 mmHg; 95% CI, 17.6–21.4; P &lt; 0.0001), fetal acidosis (pH 7.11 vs. 7.24 at 150 min, P &lt; 0.001), and decreased uterine blood flow. In the HD-DES group with maternal normotension, uterine blood flow still declined and fetal acidosis persisted, with no statistically significant difference from the group exposed to HD-DES that had maternal hypotension. There was no statistically significant difference in fetal cardiac function. Conclusion: In sheep, SIVA affects maternal hemodynamics less and provides better fetal acid/base status than high-dose desflurane. Fetal echocardiography did not reflect myocardial dysfunction in this model.

scholarly journals Profiling fetal cardiac function in twin–twin transfusion syndrome

2010 ◽  
Vol 35 (1) ◽  
pp. 19-27 ◽  
Author(s):  
J. J. Stirnemann ◽  
M. Mougeot ◽  
F. Proulx ◽  
B. Nasr ◽  
M. Essaoui ◽  
...  
Keyword(s):  
Cardiac Function ◽  
Fetal Cardiac Function

GESTATIONAL DIABETES PROGRAMS MITOCHONDRIAL DYSFUNCTION AND IMPAIRS CARDIAC FUNCTION IN THE OFFSPRING

2016 ◽  
Vol 32 (10) ◽  
pp. S82-S83
Author(s):  
S.M. Kereliuk ◽  
K.G. Cheung ◽  
B. Xiang ◽  
L.K. Cole ◽  
T.J. Pereira ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Cardiac Function ◽  
Mitochondrial Dysfunction

scholarly journals Speckle tracking for the assessment of fetal cardiac function

2011 ◽  
Vol 37 (2) ◽  
pp. 133-134 ◽  
Author(s):  
J. Simpson
Keyword(s):  
Cardiac Function ◽  
Speckle Tracking ◽  
Fetal Cardiac Function

OC08.04: Fetal cardiac function in late IUGR versus SGA defined by estimated fetal weight, cerebro-placental ratio and uterine artery Doppler

2014 ◽  
Vol 44 (S1) ◽  
pp. 19-19 ◽  
Author(s):  
M. Pérez Cruz ◽  
F. Crispi ◽  
M. Fernández ◽  
J. Parra ◽  
M. Gómez Roig ◽  
...  
Keyword(s):  
Cardiac Function ◽  
Uterine Artery ◽  
Fetal Weight ◽  
Uterine Artery Doppler ◽  
Fetal Cardiac Function ◽  
Estimated Fetal Weight
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