Differential expression of calcium-activated chloride channels (CLCA) gene family members in the small intestine of cystic fibrosis mouse models

2006 ◽  
Vol 126 (2) ◽  
pp. 239-250 ◽  
Author(s):  
Ina Leverkoehne ◽  
Hannah Holle ◽  
Friederike Anton ◽  
Achim D. Gruber
2009 ◽  
Vol 58 (3) ◽  
pp. 225-233 ◽  
Author(s):  
Hui Xie ◽  
Jian-ye Chen ◽  
Rong-cai Yuan ◽  
Yu-xiong Zhong ◽  
Hai-ling Feng ◽  
...  

2011 ◽  
Vol 158 (2) ◽  
pp. 864-875 ◽  
Author(s):  
Cornelia Chizzali ◽  
Mariam M. Gaid ◽  
Asma K. Belkheir ◽  
Robert Hänsch ◽  
Klaus Richter ◽  
...  

2021 ◽  
Vol 20 ◽  
pp. S313-S314
Author(s):  
M. Michicich ◽  
Z. Traylor ◽  
D. LePage ◽  
R. Mann ◽  
W. Jiang ◽  
...  

Genome ◽  
1999 ◽  
Vol 42 (5) ◽  
pp. 1030-1032 ◽  
Author(s):  
Achim D Gruber ◽  
Bendicht U Pauli

The CLCA gene family is a novel family of calcium-activated chloride channels. Several family members have recently been cloned from different mammalian species with distinct, highly tissue-specific expression patterns. Here, we describe radiation hybrid mapping of the human CLCA2 and CLCA3 genes using the Genebridge 4 panel. Both genes were mapped to adjacent loci on the short arm of chromosome 1 (1p22-31), a region to which the human CLCA1 had been assigned earlier. The results show clustering of all human CLCA family members known so far despite their moderately low levels of sequence homology and their heterogeneous expression patterns.Key words: radiation hybrid mapping, human chromosome 1p22-31, calcium-activated chloride channels.


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