First case of primary phyllodes tumor of the pancreas: case report and findings of immunohistochemical and ultrastructural studies

Phyllodes tumors (PTs) represent a spectrum of rare, fibroepithelial neoplasms of the breast, which can be subcategorized as benign, borderline, or malignant based on their histological appearance. Accessory breast tissue may present anywhere along the embryological mammary ridge, and at distant locations as aberrant breast tissue. We present the case of a 56-year-old lady with an umbilical mass, thought to represent a strangulated hernia. Sections showed a fibroepithelial tumor with leaf-like ducts, conspicuous mitotic activity (up to 8 per 10 high-power fields), and focal infiltration into fat. Immunohistochemical studies showed diffuse positivity of epithelial cells for estrogen receptor, mammaglobin, GCDFP-15, and CK7. These findings were consistent with a borderline PT. This is the first case report of PT presenting as an umbilical mass, and the first extramammary borderline PT described.

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The first case report of Pembrolizumab inducing thyroiditis and hypophysitis

Endocrine Abstracts ◽

10.1530/endoabs.70.aep1061 ◽

2020 ◽

Author(s):

Rahman Maraqa Sima Abdel ◽

Robert McMahon ◽

Anusha Pinjala ◽

Gastelum Alheli Arce ◽

Mohsen Zena

Keyword(s):

Case Report ◽

First Case

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Synchronous genital and facial hematidrosis in an adult female: The first case report in Egypt.

European Journal of Medical Case Reports ◽

10.24911/ejmcr/173-1538850634 ◽

2019 ◽

pp. 28-32

Author(s):

Mosaad Soliman ◽

Khaled Mowafy ◽

Reem Soliman ◽

Rana Soliman

Keyword(s):

Case Report ◽

Adult Female ◽

First Case

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Harel-Yoon syndrome: the first case report from Saudi Arabia

Journal of Biochemical and Clinical Genetics ◽

10.24911/jbcgenetics/183-1585816398 ◽

2020 ◽

pp. 22-27 ◽

Cited By ~ 1

Author(s):

Alaa AlAyed ◽

Manar Samman ◽

Abdul Peer-Zada ◽

Mohammed Almannai

Keyword(s):

Saudi Arabia ◽

Case Report ◽

First Case

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Fatal invasive pulmonary aspergillosis due to Aspergillus pseudodeflectus in a liver transplant patient: first case report

10.26226/morressier.56d5ba2fd462b80296c96a22 ◽

2016 ◽

Author(s):

Françoise Botterel Chartier

Keyword(s):

Case Report ◽

Liver Transplant ◽

Transplant Patient ◽

Invasive Pulmonary Aspergillosis ◽

Liver Transplant Patient ◽

Pulmonary Aspergillosis ◽

First Case

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Case Report: Management of a Patient with mTBI and Vestibular Hypofunction with the Binasal Occlusion Technique

Vision Development & Rehabilitation ◽

10.31707/vdr2018.4.2.p87 ◽

2018 ◽

pp. 87-90

Keyword(s):

Case Report ◽

Visual Motion ◽

Hand Movement ◽

Motion Sensitivity ◽

Vestibular Hypofunction ◽

First Case ◽

Neurological Exam ◽

History Of ◽

Occlusion Technique ◽

Visual Vertigo

Background: Binasal Occlusion (BNO) is a clinical technique used by many neurorehabilitative optometrists in patients with mild traumatic brain injury (mTBI) and increased visual motion sensitivity (VMS) or visual vertigo. BNO is a technique in which partial occluders are added to the spectacle lenses to suppress the abnormal peripheral visual motion information. This technique helps in reducing VMS symptoms (i.e., nausea, dizziness, balance difficulty, visual confusion). Case Report: A 44-year-old AA female presented for a routine eye exam with a history of mTBI approximately 33 years ago. She was suffering from severe dizziness for the last two years that was adversely impacting her ADLs. The dizziness occurred in all body positions and all environments throughout the day. She was diagnosed with vestibular hypofunction and had undergone vestibular therapy but reported little improvement. Neurological exam revealed dizziness with both OKN drum and hand movement, especially in the left visual field. BNO technique resulted in immediate relief of her dizziness symptoms. Conclusion: To our knowledge, this is the first case that illustrates how the BNO technique in isolation can be beneficial for patients with mTBI and vestibular hypofunction. It demonstrates the success that BNO has in filtering abnormal peripheral visual motion in these patients.

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Anesthesia in Carvajal syndrome; the first case report

Anaesthesia, Pain & Intensive Care ◽

10.35975/apic.v24i1.1233 ◽

2020 ◽

Vol 24 (1) ◽

pp. 105-107

Author(s):

Sedighe Shahhosseini ◽

Reza Aminnejad ◽

Amir Shafa ◽

Mehrdad Memarzade

Keyword(s):

Intensive Care ◽

Case Report ◽

Surgical Resection ◽

Genetic Disorder ◽

Anesthetic Technique ◽

Close Monitoring ◽

Anesthesia Management ◽

Rare Genetic Disorder ◽

First Case ◽

Anesthetic Considerations

Carvajal syndrome is a rare genetic disorder. Patients reporting for surgery pose some difficulties in anesthesia management. In this case report we present the case of a 12-year-old boy, who was a known case of Carvajal syndrome, referred for surgical resection of perianal condyloma. Close monitoring of hemodynamic status is the mainstay of anesthetic considerations in such patients. As in any other challenging scenario, it should be kept in mind that ‘there is no safest anesthetic agent, nor the safest anesthetic technique; there is only the safest anesthesiologist’. Citation: Shahhosseini S, Aminnejad R, Shafa A, Memarzadeh M. Anesthesia in Carvajal syndrome; the first case report. Anaesth pain intensive care 2020;24(1):___ DOI: https://doi.org/10.35975/apic.v24i1.

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Isolated Dysphagia in a Patient with Medial Medullary Infarction – Effects of Evidence-Based Dysphagia Therapy: A Case Report

Case Reports in Neurology ◽

10.1159/000513676 ◽

2021 ◽

pp. 190-199

Author(s):

Samra Hamzic ◽

Patrick Schramm ◽

Hassan Khilan ◽

Tibo Gerriets ◽

Martin Juenemann

Keyword(s):

Case Report ◽

Vascular Occlusion ◽

Evidence Based ◽

Severe Dysphagia ◽

First Case ◽

Jaw Opening ◽

Medial Medullary Infarction ◽

Dysphagia Therapy ◽

Evidence Based Therapy ◽

Medullary Infarction

Medial medullary infarction (MMI) is a vascular occlusion in the medulla oblongata leading to certain constellations of neurological symptoms and seriously affecting the patient. Effective evidence-based treatment of severe dysphagia as sole symptom of MMI has not yet been reported. This case study aims to report successful effects of evidence-based therapy based on findings of dysphagia symptoms and pathophysiology of swallowing by flexible endoscopic evaluation of swallowing (FEES) in severe isolated dysphagia after MMI. FEES was performed to evaluate swallowing pathophysiology and dysphagia symptoms in a 57-year-old male with severe dysphagia after MMI. On the basis of FEES findings, simple and high-frequent evidence-based exercises for improvement of swallowing were implemented: thermal stimulation of faucial arches, Jaw Opening Exercise, and Jaw Opening Against Resistance. After 7 weeks of high-frequent evidence-based therapy and regular FEES evaluation the patient was set on full oral diet with no evidence of aspiration risk. In a first case report of isolated dysphagia in MMI our case illustrates that high-frequent evidence-based dysphagia therapy in combination with FEES as the method to evaluate and monitor swallowing pathophysiology can lead to successful and quick rehabilitation of severely affected dysphagic patients.

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