Fatty acid composition of erythrocyte membrane lipids in healthy subjects from birth to young adulthood

2008 ◽  
Vol 168 (2) ◽  
pp. 141-147 ◽  
Author(s):  
Viktória Jakobik ◽  
István Burus ◽  
Tamás Decsi
Author(s):  
F A C Paton ◽  
J R Scaife ◽  
T Acamovic ◽  
D C Macdonald ◽  
A M Mackenzie

The vitamin E (Vit E) requirement of the neonatal calf is largely dependent upon its dietary intake of polyunsaturated fatty acid (PUFA) The PUFA content of neonatal calf plasma is low, the plasma triene:tetraene ratio of approximately 0.96 suggests a possible essential fatty acid deficiency, however within 3-4 days postpartum the ratio is markedly reduced to approximately 0.12 (Noble 1984). In spring-calving cows turned out to grass just prior to calving the sudden change to a diet rich in PUFA has a significant influence on the PUFA content of colostrum and milk and thus the Vit E requirement of the newborn calf. A study was conducted to examine the effects of different dietary ratios of Vit E to C18:2 on the growth performance; immunoglobulin status; fatty acid and retinol, Vit E and β-carotene profiles of blood plasma and erythrocyte membrane lipids (EML), and lipid oxidation of erythrocyte membranes. The effect of turn-out to grass on cow plasma fatty acid composition was also studied. The preliminary results of this study are presented below.


2010 ◽  
Vol 23 (1) ◽  
pp. 3-17 ◽  
Author(s):  
P. Mayzaud ◽  
S. Lacombre ◽  
M. Boutoute

AbstractChanges in adult weight, lipid and fatty acid composition per lipid class were studied over a complete seasonal cycle in Drepanopus pectinatus Brady. This copepod displayed a strong seasonality in adult individual weight and total lipid content. Stages C3 to adult from a summer cohort were compared in terms of lipid and fatty acid structure. Changes in lipid content were related to wax esters and polar lipids (PL) while triacylglycerols (TAG) and cholesterol remained minor constituents except at the end of winter. Changes in fatty acid composition of different lipid classes showed that food limitation in winter was high enough to affect 22:6n-3 (DHA) content in PL, and provoke accumulation of maximal percentages of bacterial marker as branched acids. Composition of TAG followed closely the changes in trophic interactions as diatom and flagellate markers dominated in spring and summer while bacterial and detritus particle markers dominated in late winter. The composition of wax esters followed the same seasonal succession but with a lower level of turn over time and shifted characteristics (bacterial markers) from winter to spring individuals when compared to TAG. Ontogenetic changes showed high triacylglycerols content in younger C3 stages and increasing wax esters with increasing developmental stages. Fatty acid composition of PL showed low percentages of EPA and DHA in stage C3, and recovery of high levels of DHA for stage C4 or 20:5n-3 (EPA) at stage C5. The same trend was observed for 18:4n-3. The reverse pattern was noted for the n-6 polyunsaturated acids (PUFA) suggesting a greater requirement in younger stages. Fatty acid partitioning between neutral and PL suggested essential fatty acids selective incorporation from neutral classes into membrane lipids.


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