Fatty acid composition of plasma lipid classes in healthy subjects from birth to young adulthood

1994 ◽  
Vol 153 (7) ◽  
pp. 520-525 ◽  
Author(s):  
B. Koletzko ◽  
T. Decsi
1973 ◽  
Vol 51 (11) ◽  
pp. 1509-1514 ◽  
Author(s):  
Claude Allard ◽  
Jean Davignon ◽  
Yves L. Marcel ◽  
Claude Goulet ◽  
Kanta Kuba ◽  
...  

The plasma fatty acid composition of the cholesteryl esters triglycerides, and total phospholipid was studied by gas–liquid chromatography in clinically healthy subjects and coronary patients; all of whom had had a recent selective coronary arteriography. The fatty acid composition of the same lipid classes mentioned above was investigated in the different types of hyperlipoproteinemia. All the subjects or patients investigated were on a regular diet. The fatty acid patterns in the various lipid classes were found the same in coronary patients and in healthy subjects. However, great differences were noted in the fatty acid profiles in the various types of hyperlipoproteinemia. Noteworthy was the fact that type II (especially type IIa) contained the greatest proportion of linoleic acid in all lipid classes. This study indicated again biochemical heterogeneity within types of primary hyperlipoproteinemias and also between types IIa and IIb.


Pancreatology ◽  
2010 ◽  
Vol 10 (5) ◽  
pp. 580-585 ◽  
Author(s):  
Tamas Marosvolgyi ◽  
Gabor Horvath ◽  
Aniko Dittrich ◽  
Judit Cseh ◽  
Zsuzsanna Lelovics ◽  
...  

2007 ◽  
Vol 97 (6) ◽  
pp. 1154-1161 ◽  
Author(s):  
Mária Figler ◽  
Beata Gasztonyi ◽  
Judit Cseh ◽  
Gábor Horváth ◽  
Andrea G. Kisbenedek ◽  
...  

In order to establish the biochemical basis for dietary interventions, we investigated the fatty acid composition of plasma lipid classes in patients with inactive inflammatory bowel disease. In this cross-sectional study thirty patients with ulcerative colitis (UC), twenty-one with Crohn disease (CD) and twenty-four controls were investigated (mean age: UC, 40·8 (sd12·1); CD, 37·6 (sd11·0); control, 31·5 (sd8·4) years). Fatty acid composition of plasma lipids was determined by high-resolution capillary GLC. In plasma phospholipids, significantly higher values of eicosapentaenoic (20 : 5n-3), docosapentaenoic (22 : 5n-3) and γ-linolenic (18 : 3n-6) acids were found in control patients and patients with UC as compared to patients with CD [median % (weight by weight), controlv.UCv.CD : 20 : 5n-3, 0·09 (interquartile range (IQR) 0·05)v.0·14 (IQR 0·10)v.0·16 (IQR 0·10),P < 0·05; 22 : 5n-3, 0·14 (IQR 0·10)v.0·27 (IQR 0·16)v.0·31 (IQR 0·10),P < 0·001; 18 : 3n-6, 0·02 (IQR 0·02)v.0·03 (IQR 0·02)v.0·05 (IQR 0·03),P < 0·05]. When compared to the control, values of the principaln-3 andn-6 long-chain PUFA, arachidonic acid (20 : 4n-6) and DHA (22 : 6n-3) were significantly higher in patients with UC but not in patients with CD [median % (w/w), UCv.control: 20 : 4n-6, 8·43 (IQR 3·23)v.6·92 (IQR 2·96),P < 0·05; 22 : 6n-3, 1·22 (IQR 0·56)v.0·73 (IQR 0·39),P < 0·05]. As seen there are considerable differences between the long-chain PUFA status of patients suffering from UC or CD. The data obtained in the present study do not support the concept of eicosapentaenoic acid or DHA deficiency in patients with either UC or CD.


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