scholarly journals Electrical stimulation therapy of the lower esophageal sphincter is successful in treating GERD: final results of open-label prospective trial

2012 ◽  
Vol 27 (4) ◽  
pp. 1083-1092 ◽  
Author(s):  
Leonardo Rodríguez ◽  
Patricia Rodriguez ◽  
Beatriz Gómez ◽  
Juan C. Ayala ◽  
Jorge Saba ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Lower Esophageal Sphincter ◽  
Prospective Trial ◽  
Open Label ◽  
Electrical Stimulation Therapy ◽  
Esophageal Sphincter

Electrical Stimulation Therapy (EST) of the Lower Esophageal Sphincter (LES) for Refractory Gerd and Two Year Results of an International Multicenter Trial

2017 ◽  
Vol 152 (5) ◽  
pp. S470 ◽  
Author(s):  
Peter D. Siersema ◽  
Albert J. Bredenoord ◽  
José M. Conchillo ◽  
Jelle Ruurda ◽  
Mark van Berge Henegouwen ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Lower Esophageal Sphincter ◽  
Multicenter Trial ◽  
Electrical Stimulation Therapy ◽  
Refractory Gerd ◽  
Esophageal Sphincter ◽  
International Multicenter

scholarly journals Electrical stimulation therapy of the lower esophageal sphincter in GERD patients—a prospective single-center study

2020 ◽  
Author(s):  
Matthias Paireder ◽  
Ivan Kristo ◽  
Milena Nikolic ◽  
Gerd Jomrich ◽  
Johannes Steindl ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Side Effects ◽  
Lower Esophageal Sphincter ◽  
High Rate ◽  
Single Center ◽  
Electrical Stimulation Therapy ◽  
Novel Technique ◽  
Single Center Study ◽  
Esophageal Sphincter ◽  
Center Study

Summary Background Electrical stimulation therapy (EST) of the lower esophageal sphincter (LES) for gastro esophageal reflux disease (GERD) treatment increases LES pressure through chronic stimulation, with a low risk for gastrointestinal side effects and preservation of hiatal anatomy. The aim of this study was to evaluate the efficacy and safety of this novel technique in a high-output specialized reflux center. Methods This is a prospective single-center study including GERD patients indicated for anti-reflux therapy who consented to undergo LES-EST. Patients underwent prospective scheduled follow-up visits including interrogation of the stimulation device, clinical examination, and assessment of health-related quality of life (HRQL). Results Within a 4-year period, 37 LES-EST implantations were performed. The majority of patients were male (54.1%), mean BMI was 25.8 (SD 4.4), and mean age was 54.0 (SD 15.8). The median GERD HRQL composite score was 41 (IQR 21–49). Median total % of pH <4 was 10.1 (IQR 4.4–17.3). Six (16.2%) individuals underwent explantation of the entire system (IPG and leads) due to technical defect (n = 4) or failure of therapy (n = 2). HRQL score improved from 41 (IQR 21–49) to 8.50 (IQR 4.25–20.5, p < 0.001) and 9 (23.7%) patients were on at least occasional PPI treatment. Conclusion Due to the low rate of GI side effects and its minimal invasive character preserving the hiatal anatomy, this novel technique might find its place in anti-reflux surgery. However, the considerably high rate of device dysfunction needs further investigation.

Electrical Stimulation Therapy (EST) Significantly and Consistently Increases Lower Esophageal Sphincter (LES) Pressure in GERD Patients

2010 ◽  
Vol 105 ◽  
pp. S18-S19
Author(s):  
Virender Sharma ◽  
Rupa Banerjee ◽  
Manoel GalvaoNeto ◽  
Leonardo Grunert ◽  
Nitesh Pratap ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Lower Esophageal Sphincter ◽  
Electrical Stimulation Therapy ◽  
Esophageal Sphincter

Electrical Stimulation Therapy (EST) of the Lower Esophageal Sphincter (LES) Is Successful in Treating GERD: Long-term 2-year Results

2013 ◽  
Vol 108 ◽  
pp. S27 ◽  
Author(s):  
Leonardo Rodriguez ◽  
Patricia Rodriguez ◽  
Beatriz Gomez ◽  
Manoel Galvao ◽  
Michael Crowell ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Lower Esophageal Sphincter ◽  
Electrical Stimulation Therapy ◽  
Esophageal Sphincter

Su1123 Electrical Stimulation Therapy (EST) of the Lower Esophageal Sphincter (LES) is Successful in Treating GERD - Long-term 4 Year Results

2016 ◽  
Vol 150 (4) ◽  
pp. S476 ◽  
Author(s):  
Leonardo Rodriguez ◽  
Patricia Rodriguez ◽  
Beatrice Gómez ◽  
Manoel Galvao Neto ◽  
Michael Crowell ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Lower Esophageal Sphincter ◽  
Electrical Stimulation Therapy ◽  
Esophageal Sphincter
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