scholarly journals Long-term renal outcomes of APRT deficiency presenting in childhood

2018 ◽  
Vol 34 (3) ◽  
pp. 435-442 ◽  
Author(s):  
Hrafnhildur Linnet Runolfsdottir ◽  
Runolfur Palsson ◽  
Inger MSch Agustsdottir ◽  
Olafur S Indridason ◽  
Vidar O Edvardsson
Keyword(s):  
Renal Outcomes ◽  
Aprt Deficiency

522-P: Long-Term Renal Outcomes in Young Onset Type 2 Diabetes

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 522-P
Author(s):  
TIMOTHY MIDDLETON ◽  
STEVE CHADBAN ◽  
LYNDA M. MOLYNEAUX ◽  
MARIO I. D'SOUZA ◽  
MARIA I. CONSTANTINO ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Young Onset ◽  
Onset Type ◽  
Renal Outcomes

scholarly journals Long Term Renal Outcomes in Children with Acute Kidney Injury Post-Cardiac Surgery

2021 ◽  
Author(s):  
Sidharth Kumar Sethi ◽  
Rajesh Sharma ◽  
Aditi Gupta ◽  
Abhishek Tibrewal ◽  
Romel Akole ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cardiac Surgery ◽  
Kidney Injury ◽  
Renal Outcomes ◽  
Post Cardiac Surgery

Snake envenomation-induced acute kidney injury: prognosis and long-term renal outcomes

2021 ◽  
pp. postgradmedj-2020-139021
Author(s):  
Manoj Kumar ◽  
Maasila Arcot Thanjan ◽  
Natarajan Gopalakrishnan ◽  
Dhanapriya Jeyachandran ◽  
Dineshkumar Thanigachalam ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Long Term Outcomes ◽  
Urine Protein ◽  
Renal Outcomes ◽  
Snake Envenomation ◽  
The Mean ◽  
New Onset

BackgroundSnake bite continues to be a significant cause of acute kidney injury (AKI) in India. There is paucity of data regarding long-term outcomes of such patients. In this study, we aim to assess the prognosis and long-term renal outcomes of such patients.MethodsWe analysed the hospital records of snake envenomation-induced AKI from January 2015 to December 2018. Predictors of in-hospital mortality were assessed. Survivors were advised to visit follow-up clinic to assess their kidney function.ResultsThere were 769 patients with evidence of envenomation and of them, 159 (20.7%) had AKI. There were 112 (70.4%) males. Mortality occurred in 9.4% of patients. Logistic regression analysis identified shock (OR 51.949, 95% CI 4.297 to 628.072) and thrombocytopenia (OR 27.248, 95% CI 3.276 to 226.609) as predictors of mortality. Forty-three patients attended the follow-up. The mean follow-up duration was 30.4±15.23 months. Adverse renal outcomes (eGFR <60 mL/min/1.73 m2 or new-onset hypertension (HTN) or pre-HTN or urine protein creatinine ratio >0.3) occurred in 48.8% of patients. Older age (mean age (years) 53.3 vs 42.8, p=0.004) and longer duration on dialysis (median duration (days) 11.5 vs 5, p=0.024) were significantly associated with adverse renal outcomes.ConclusionsThe incidence of AKI in snake envenomation was 20.7%. The presence of shock and thrombocytopenia were associated with mortality. Adverse renal outcomes occurred in 48.8% of patients in the long term.

scholarly journals The Impact of Endovascular Aneurysm Repair on Long Term Renal Function Based on Hard Renal Outcomes

2019 ◽  
Vol 70 (4) ◽  
pp. 1380
Author(s):  
E.R. Charles ◽  
D. Lui ◽  
J. Delf ◽  
R.D. Sayers ◽  
M.J. Bown ◽  
...  
Keyword(s):  
Renal Function ◽  
Endovascular Aneurysm Repair ◽  
Renal Outcomes ◽  
Aneurysm Repair ◽  
The Impact

scholarly journals The Role of a “Treat-to-Target” Approach in the Long-Term Renal Outcomes of Patients with Gout

2019 ◽  
Vol 8 (7) ◽  
pp. 1067
Author(s):  
Woo-Joong Kim ◽  
Jung Soo Song ◽  
Sang Tae Choi
Keyword(s):  
Renal Function ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Multivariable Analysis ◽  
Serum Urate ◽  
Disease Stage ◽  
Treat To Target ◽  
Renal Outcomes ◽  
Significant Difference

Background: Although gout is accompanied by the substantial burden of kidney disease, there are limited data to assess renal function as a therapeutic target. This study evaluated the importance of implementing a “treat-to-target” approach in relation to renal outcomes. Methods: Patients with gout who underwent continuous urate-lowering therapy (ULT) for at least 12 months were included. The effect of ULT on renal function was investigated by means of a sequential comparison of the estimated glomerular filtration rate (eGFR). Results: Improvement in renal function was only demonstrated in subjects in whom the serum urate target of <6 mg/dL was achieved (76.40 ± 18.81 mL/min/1.73 m2 vs. 80.30 ± 20.41 mL/min/1.73 m2, p < 0.001). A significant difference in the mean change in eGFR with respect to serum urate target achievement was shown in individuals with chronic kidney disease stage 3 (−0.35 ± 3.87 mL/min/1.73 m2 vs. 5.33 ± 11.64 mL/min/1.73 m2, p = 0.019). Multivariable analysis predicted that patients ≥65 years old had a decreased likelihood of improvement (OR 0.31, 95% CI 0.13–0.75, p = 0.009). Conclusions: The “treat-to-target” approach in the long-term management of gout is associated with better renal outcomes, with a greater impact on those with impaired renal function.

scholarly journals 445 Predictors of good long-term renal outcomes

2017 ◽  
Author(s):  
W Fung ◽  
J Su ◽  
Z Touma ◽  
D Gladman
Keyword(s):  
Renal Outcomes

scholarly journals Hyperfiltration predicts long-term renal outcomes in humanized sickle cell mice

2019 ◽  
Vol 3 (9) ◽  
pp. 1460-1475 ◽  
Author(s):  
Malgorzata Kasztan ◽  
Brandon M. Fox ◽  
Jeffrey D. Lebensburger ◽  
Kelly A. Hyndman ◽  
Joshua S. Speed ◽  
...  
Keyword(s):  
Sickle Cell ◽  
Kidney Injury ◽  
Kidney Damage ◽  
Tubular Injury ◽  
Renal Outcomes ◽  
Key Points ◽  
Glomerular Damage

Key Points In HbSS mice, hyperfiltration predicts long-term kidney damage and tubular injury occurs prior to glomerular damage. Sex contributes to the progression of kidney injury in HbSS mice.

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