scholarly journals Validity and interobserver agreement of a new radiographic grading system for intervertebral disc degeneration: Part I. Lumbar spine

2005 ◽  
Vol 15 (6) ◽  
pp. 720-730 ◽  
Author(s):  
Hans-Joachim Wilke ◽  
Friederike Rohlmann ◽  
Cornelia Neidlinger-Wilke ◽  
Karin Werner ◽  
Lutz Claes ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Interobserver Agreement ◽  
Grading System ◽  
Radiographic Grading

scholarly journals Validity and interobserver agreement of a new radiographic grading system for intervertebral disc degeneration: Part I. Lumbar spine

2006 ◽  
Vol 15 (6) ◽  
pp. 731-731 ◽  
Author(s):  
Hans-Joachim Wilke ◽  
Friederike Rohlmann ◽  
Cornelia Neidlinger-Wilke ◽  
Karin Werner ◽  
Lutz Claes ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Interobserver Agreement ◽  
Grading System ◽  
Radiographic Grading

scholarly journals Validity and interobserver agreement of a new radiographic grading system for intervertebral disc degeneration: Part III. Thoracic spine

2021 ◽  
Author(s):  
Christian Liebsch ◽  
Youping Tao ◽  
Annette Kienle ◽  
Hans-Joachim Wilke
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Interobserver Agreement ◽  
Weighted Kappa ◽  
Intervertebral Discs ◽  
Height Loss ◽  
Grading System ◽  
Perfect Agreement ◽  
Radiographic Grading

Abstract Purpose The aim of this study was to assess the validity and objectivity of a new quantitative radiographic grading system for thoracic intervertebral disc degeneration. Methods The new grading system involves the measurement variables “Height loss” and “Osteophyte formation”, which are determined from lateral radiographs, resulting in the “Overall degree of degeneration” on a four-point scale from 0 (no degeneration) to 3 (severe degeneration). Validation was performed by comparing the radiographic degrees of degeneration of 54 human intervertebral discs to the respective macroscopic degrees, which were defined as the “real” degrees of degeneration. Interobserver agreement was examined using radiographs of 135 human thoracic intervertebral discs. Agreement was quantified by means of quadratically weighted Kappa coefficients with 95% confidence limits (CL). Results Validation revealed almost perfect agreement between the radiographic and the macroscopic overall degrees of degeneration (Kappa 0.968, CL 0.944–0.991), while the macroscopic grades tended to be underestimated in low degeneration grades. Radiographic grading of two independent observers also exhibited almost perfect agreement (Kappa 0.883, CL 0.824–0.941) as well as tendencies towards rater-dependent differences in low degeneration grades. Conclusion The new quantitative radiographic grading scheme represents a valid, reliable, and almost objective method for assessing the degree of degeneration of individual thoracic intervertebral discs. Potential effects of interindividual variations and the radiographic superimposition of anatomical structures represent a limitation of this method should be taken into account when using the grading system for clinical and experimental purposes, especially with regard to specific morphological as well as patient- and donor-specific characteristics.

scholarly journals Validity and interobserver agreement of a new radiographic grading system for intervertebral disc degeneration: Part II. Cervical spine

2006 ◽  
Vol 15 (6) ◽  
pp. 732-741 ◽  
Author(s):  
Annette Kettler ◽  
Friederike Rohlmann ◽  
Cornelia Neidlinger-Wilke ◽  
Karin Werner ◽  
Lutz Claes ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Interobserver Agreement ◽  
Grading System ◽  
Radiographic Grading

Modified Pfirrmann Grading System for Lumbar Intervertebral Disc Degeneration

Spine ◽  
2007 ◽  
Vol 32 (24) ◽  
pp. E708-E712 ◽  
Author(s):  
James F. Griffith ◽  
Yi-Xiang J. Wang ◽  
Gregory E. Antonio ◽  
Kai Chow Choi ◽  
Alfred Yu ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Grading System ◽  
Lumbar Intervertebral Disc

scholarly journals Comparison of MRI cross-sectional area and functions of core muscles among asymptomatic individuals with and without lumbar intervertebral disc degeneration

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Gyeong-tae Gwak ◽  
Ui-jae Hwang ◽  
Sung-hoon Jung ◽  
Hyun-a Kim ◽  
Jun-hee Kim ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Endurance Test ◽  
Cross Sectional ◽  
Significant Difference ◽  
Asymptomatic Individuals

Abstract Background Previous studies suggested that patients with symptomatic intervertebral disc degeneration (IDD) of lumbar spine have reduced cross-sectional area (CSA) and functions of core muscles. However, reduced CSA and functions of core muscles have been observed not only in patients with symptomatic IDD but also in patients with other subgroups of low back pain (LBP). Thus, it is uncertain whether reduced CSA and functions of core muscles lead to IDD and LBP, or pain leads to reduced CSA and functions of core muscles in patients with symptomatic IDD. Therefore, this study aimed to compare the CSA and functions of core muscles between asymptomatic participants with and without IDD in magnetic resonance imaging (MRI). Methods Twenty asymptomatic participants (12 men and 8 women) participated in this study. Ten participants had asymptomatic IDD at L4–5. The others were healthy controls (without IDD at all levels of lumbar spine). The CSA of core muscles was measured using MRI. Maximal isometric trunk flexor strength and side bridge strength were measured by a Smart KEMA strength sensor. Trunk flexor endurance test, side bridge endurance test and plank endurance test were used to measure core endurance. Double legs loading test was used to measure core stability. Mann-Whitney U test was used to compare the differences between two groups. Results There were no significant differences in core muscle functions between the two groups (p > 0.05). Moreover, there was no significant difference in CSA between the two groups (p > 0.05). Conclusions There was no significant difference in CSA and core muscle functions between asymptomatic participants with and without IDD. These findings indicate that a degenerative or bulging disc in asymptomatic individuals has little effect on CSA and functions of core muscles, especially in young age. Therefore, the general core endurance test or strength test could not differentiate asymptomatic people with and without IDD of lumbar spine. Trial registration number Clinical Research information Service. KCT0004061. Registered 13 June 2019. retrospectively registered.

Effects of motion segment level, Pfirrmann intervertebral disc degeneration grade and gender on lumbar spine kinematics

2016 ◽  
Vol 34 (8) ◽  
pp. 1389-1398 ◽  
Author(s):  
Muturi G. Muriuki ◽  
Robert M. Havey ◽  
Leonard I. Voronov ◽  
Gerard Carandang ◽  
Michael R. Zindrick ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Motion Segment ◽  
Spine Kinematics ◽  
And Gender

COL9A3 Gene Polymorphism and Obesity in Intervertebral Disc Degeneration of the Lumbar Spine: Evidence of Gene-Environment Interaction

Spine ◽  
2002 ◽  
Vol 27 (23) ◽  
pp. 2691-2696 ◽  
Author(s):  
Svetlana Solovieva ◽  
Jaana Lohiniva ◽  
Päivi Leino-Arjas ◽  
Raili Raininko ◽  
Katariina Luoma ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Gene Polymorphism ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Environment Interaction ◽  
Gene Environment Interaction ◽  
Gene Environment

scholarly journals The effect of training on lumbar spine posture and intervertebral disc degeneration in active-duty Marines

Ergonomics ◽  
2016 ◽  
Vol 60 (8) ◽  
pp. 1055-1063 ◽  
Author(s):  
Ana E. Rodriguez-Soto ◽  
David B. Berry ◽  
Rebecca Jaworski ◽  
Andrew Jensen ◽  
Christine B. Chung ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Active Duty

scholarly journals Correlation Analysis of Intervertebral Disc Degeneration with HTRA1 and HAPLN1 Gene Polymorphisms

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Tuanmao Guo ◽  
Yanli Xing ◽  
Zhongning Chen ◽  
Haiyun Zhu
Keyword(s):  
Back Pain ◽  
Lumbar Spine ◽  
Correlation Analysis ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Gene Polymorphisms ◽  
Intervertebral Disc Degeneration ◽  
Clinical Manifestations ◽  
Degenerative Changes ◽  
Leg Pain

The lumbar spine, an important part of the body's motor mechanism, is more susceptible to damage as it bears most of the body's load. Age can cause clinical manifestations such as neurological impairment, back and leg pain in the lumbar spine. External forces result in nucleus pulposus out, destruction of the intervertebral disc fibrous ring, and gradual aging and damage. Lumbar degenerative change is a common middle-aged and old-aged disease, and its clinical symptoms on the initial stage are not obvious, but it becomes more and more serious as they get older. Patients with severe lumbar degenerative changes will appear symptoms such as urinary and fecal incontinence, lower extremity numbness, back pain, and sexual dysfunction. The main reason for back pain and leg pain is the degenerative changes in the lumbar intervertebral discs, at the same time which also leads to patients' lumbar instability. This study focuses on the correlation analysis of intervertebral disc degeneration with HTRA1 and HAPLN1 gene polymorphisms.

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