Acute kidney injury after colorectal surgery with an enhanced recovery pathway

Surgery Today ◽  
2020 ◽  
Author(s):  
Kai Su ◽  
Fu-Shan Xue ◽  
Zhao-Jing Xue ◽  
Lei Wan
2020 ◽  
Vol 63 (2) ◽  
pp. 233-241 ◽  
Author(s):  
Jameson G.D. Wiener ◽  
Lauren Goss ◽  
Tyler S. Wahl ◽  
Morgan A. Terry ◽  
Kaitlin G. Burge ◽  
...  

Surgery Today ◽  
2020 ◽  
Author(s):  
Andrés Zorrilla-Vaca ◽  
Gabriel E. Mena ◽  
Javier Ripolles-Melchor ◽  
Juan Victor Lorente ◽  
Juan José M. Ramirez-Rodriguez ◽  
...  

2019 ◽  
Vol 85 (2) ◽  
pp. 156-161 ◽  
Author(s):  
Crystal P. Koerner ◽  
Alexandra G. Lopez-Aguiar ◽  
Mohammad Zaidi ◽  
Shelby Speegle ◽  
Glen Balch ◽  
...  

Minimizing perioperative fluid administration is a key component of enhanced recovery after surgery protocols (ERAS). Acute kidney injury (AKI) is a major cause of morbidity and mortality in hospitalized patients. Our aim was to assess the association of ERAS with the incidence and severity of AKI in patients undergoing elective colorectal surgery. In this single-study retrospective review, patients undergoing colorectal surgery from 2013 to 2017 were included. Primary endpoint was postoperative AKI. Secondary outcomes were hospital length of stay (LOS) and 30-day readmission. Baseline demographics and procedure types were similar between both groups. AKI was higher in the ERAS versus non-ERAS group (23 vs 9%; P = 0.002). Factors associated with increased risk of AKI on univariate regression included presence of preoperative cardiovascular risk factors (hazard ratio (HR) 3.5; 95% CI 1.3–9.7; P < 0.01), more complex colorectal operations (HR 5.1; 95% CI 1.6–16.1; P < 0.01), and management with an ERAS pathway (HR 2.9; 95% CI 1.5–5.8; P < 0.01). On multi-variable analysis, ERAS remained a significant risk factor for developing AKI (HR 3.44; 95% CI 1.5–7.7; P < 0.01). ERAS patients had a shorter hospital LOS (3.9 vs 5.9 days, P < 00.1) compared with non-ERAS patients, with no difference in 30-day readmission rates (11.5 vs 10.7%; P = 0.98). Although the incidence of AKI is higher in patients treated with ERAS protocols, the majority represent minor elevations in baseline serum creatinine and did not affect the reduction in hospital LOS associated with ERAS. Given the potential association of AKI, however, with increased long-term morbidity and mortality, ERAS protocols should be optimized to prevent postoperative AKI.


2018 ◽  
Vol 33 (9) ◽  
pp. 1259-1267 ◽  
Author(s):  
Joseph H. Marcotte ◽  
Kinjal Patel ◽  
Ronak Desai ◽  
John P. Gaughan ◽  
Deviney Rattigan ◽  
...  

Author(s):  
Paul Andrew Drakeford ◽  
Shu Qi Tham ◽  
Jia Li Kwek ◽  
Vera Lim ◽  
Chien Joo Lim ◽  
...  

2019 ◽  
Vol 43 (5) ◽  
pp. 1207-1215 ◽  
Author(s):  
Fabian Grass ◽  
Jenna K. Lovely ◽  
Jacopo Crippa ◽  
Kellie L. Mathis ◽  
Martin Hübner ◽  
...  

2021 ◽  
Vol 108 (Supplement_1) ◽  
Author(s):  

Abstract Introduction The aim of this study was to re-audit the rates of acute kidney injury (AKI) after elective colorectal surgery, following local presentations of results. Method Outcomes After Kidney injury in Surgery (OAKS) and Ileus Management International (IMAGINE), were prospective multicentre audits on consecutive elective colorectal resections, in the UK and Ireland. These were performed over 3-month periods in 2015 and 2018 respectively. During the interim period, results were presented at participating centres to stimulate local quality improvement initiatives. Risk-adjusted 7-day postoperative AKI rates were calculated through multilevel logistic regression based on the OAKS prognostic score. Result Of the 4,917 patients included, 3,133 (63.7%) originated from OAKS and 1,784 (36.3%) from IMAGINE. On univariate analysis, there was no significant difference (p=0.737) in the 7-day AKI rate between OAKS (n=346, 11.8%) and IMAGINE (n=205, 11.5%). However, the risk-adjusted AKI rate in IMAGINE was significantly lower compared to OAKS (-1.8%, 95% CI: -2.3% to -1.3%, p&lt;0.001). Of 47 centres (40.1%) with a recorded local presentation, there was no significant difference in the subsequent AKI rate in IMAGINE (-0.7%, -2.0% to 0.6%, p=0.278). Conclusion Rates of AKI after elective colorectal surgery significantly reduced on re-audit. However, this may be related to increased awareness from participation or national quality improvement initiatives, rather than local presentation of results. Abbrev. AKI - Acute Kidney Injury, OAKS - Outcomes After Kidney injury in Surgery, IMAGINE - Ileus Management International Take-home message Risk-adjusted AKI rates significantly reduced on re-audit, however, this was most likely due to factors separate from the local presentation of initial results.


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