Transcription factor AP-2� genotype, striatal dopamine D2 receptor density and cerebrospinal fluid monoamine metabolite concentrations in humans

2004 ◽  
Vol 111 (4) ◽  
pp. 537-545 ◽  
Author(s):  
M. Damberg ◽  
C. Bergg�rd ◽  
L. Farde ◽  
G. C. Sedvall ◽  
E. G. J�nsson
Keyword(s):  
Cerebrospinal Fluid ◽  
Transcription Factor ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Striatal Dopamine ◽  
Receptor Density ◽  
Dopamine D2 ◽  
Metabolite Concentrations ◽  
Monoamine Metabolite

Correlation between fine motor activity and striatal dopamine D2 receptor density in patients with schizophrenia and healthy controls

2003 ◽  
Vol 123 (3) ◽  
pp. 191-197 ◽  
Author(s):  
Yen Kuang Yang ◽  
Nan Tsing Chiu ◽  
Chwen Cheng Chen ◽  
Mitchell Chen ◽  
Tzung Lieh Yeh ◽  
...  
Keyword(s):  
Motor Activity ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Striatal Dopamine ◽  
Fine Motor ◽  
Healthy Controls ◽  
Receptor Density ◽  
Dopamine D2 ◽  
Fine Motor Activity

Correlation between striatal dopamine D2 receptor density and neuroticism in community volunteers

2005 ◽  
Vol 138 (3) ◽  
pp. 259-264 ◽  
Author(s):  
I Hui Lee ◽  
Chwen Cheng Cheng ◽  
Yen Kuang Yang ◽  
Tzung Lieh Yeh ◽  
Po See Chen ◽  
...  
Keyword(s):  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Striatal Dopamine ◽  
Receptor Density ◽  
Dopamine D2 ◽  
Community Volunteers

scholarly journals Effect of Zishenpingchan Granule on Neurobehavioral Manifestations and the Activity and Gene Expression of Striatal Dopamine D1 and D2 Receptors of Rats with Levodopa-Induced Dyskinesias

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Qing Ye ◽  
Xiao-Lei Yuan ◽  
Jie Zhou ◽  
Can-xing Yuan ◽  
Xu-ming Yang
Keyword(s):  
Gene Expression ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
D2 Receptors ◽  
Striatal Dopamine ◽  
Control Group ◽  
Indirect Pathway ◽  
Dopamine D2 ◽  
D1 And D2 Receptors ◽  
Neurobehavioral Manifestations

This study was performed to observe the effects of Zishenpingchan granule on neurobehavioral manifestations and the activity and gene expression of striatal dopamine D1 and D2 receptors of rats with levodopa-induced dyskinesias (LID). We established normal control group, LID model group, and TCM intervention group. Each group received treatment for 4 weeks. Artificial neural network (ANN) was applied to excavate the main factor influencing variation in neurobehavioral manifestations of rats with LID. The results showed that overactivation in direct pathway mediated by dopamine D1 receptor and overinhibition in indirect pathway mediated by dopamine D2 receptor may be the main mechanism of LID. TCM increased the efficacy time of LD to ameliorate LID symptoms effectively mainly by upregulating dopamine D2 receptor gene expression.

Sign in / Sign up

Export Citation Format

Share Document