Plasma BDNF levels are correlated with aggressiveness in patients with amnestic mild cognitive impairment or Alzheimer disease

2013 ◽  
Vol 121 (4) ◽  
pp. 433-441 ◽  
Author(s):  
Tomoyuki Nagata ◽  
Nobuyuki Kobayashi ◽  
Shunichiro Shinagawa ◽  
Hisashi Yamada ◽  
Kazuhiro Kondo ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Alzheimer Disease ◽  
Amnestic Mild Cognitive Impairment

scholarly journals Plasma amino acid concentrations in patients with amnestic mild cognitive impairment or Alzheimer disease

2004 ◽  
Vol 80 (2) ◽  
pp. 483-488 ◽  
Author(s):  
Giovanni Ravaglia ◽  
Paola Forti ◽  
Fabiola Maioli ◽  
Giampaolo Bianchi ◽  
Mabel Martelli ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Amino Acid ◽  
Alzheimer Disease ◽  
Amnestic Mild Cognitive Impairment ◽  
Plasma Amino Acid ◽  
Amino Acid Concentrations

scholarly journals Frontal White Matter Hyperintensity Is Associated with Verbal Aggressiveness in Elderly Women with Alzheimer Disease and Amnestic Mild Cognitive Impairment

2018 ◽  
Vol 8 (1) ◽  
pp. 138-150 ◽  
Author(s):  
Noriko Ogama ◽  
Takashi Sakurai ◽  
Naoki Saji ◽  
Toshiharu Nakai ◽  
Shumpei Niida ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
White Matter ◽  
Alzheimer Disease ◽  
Frontal Lobe ◽  
Brain Atrophy ◽  
Amnestic Mild Cognitive Impairment ◽  
White Matter Hyperintensity ◽  
Verbal Aggressiveness ◽  
The Impact

Background/Aims: Behavioral and psychological symptoms of dementia (BPSD) are exhibited in most patients with Alzheimer disease (AD). Although white matter hyperintensity (WMH) is often observed with AD, the precise role of WMH in BPSD remains unclear. The current study aimed to identify the impact of regional WMH on specific features of BPSD in persons with mild to moderate AD and amnestic mild cognitive impairment (aMCI). Methods: A sample of 256 female outpatients with AD (n = 217) and aMCI (n = 39) were recruited. We assessed BPSD using the Dementia Behavior Disturbance Scale. WMH and brain atrophy were evaluated using an automatic segmentation program. Regional WMH was evaluated as periventricular hyperintensity (PVH) and deep WMH in frontal, temporal, occipital, and parietal lobes. Results: Whole-brain WMH was associated with verbal aggressiveness. In multivariate analysis, PVH in the frontal lobe was independently associated with verbal aggressiveness after adjustment for brain atrophy and clinical confounders. Conclusion: The current results indicated that PVH in the frontal lobe was independently associated with verbal aggressiveness.

scholarly journals Association Between Olfactory Dysfunction and Amnestic Mild Cognitive Impairment and Alzheimer Disease Dementia

2016 ◽  
Vol 73 (1) ◽  
pp. 93 ◽  
Author(s):  
Rosebud O. Roberts ◽  
Teresa J. H. Christianson ◽  
Walter K. Kremers ◽  
Michelle M. Mielke ◽  
Mary M. Machulda ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Alzheimer Disease ◽  
Amnestic Mild Cognitive Impairment ◽  
Olfactory Dysfunction

The Uncinate Fasciculus as a Predictor of Conversion from Amnestic Mild Cognitive Impairment to Alzheimer Disease

2014 ◽  
Vol 25 (5) ◽  
pp. 748-753 ◽  
Author(s):  
Kazuko Hiyoshi-Taniguchi ◽  
Naoya Oishi ◽  
Chihiro Namiki ◽  
Jun Miyata ◽  
Toshiya Murai ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Alzheimer Disease ◽  
Amnestic Mild Cognitive Impairment ◽  
Uncinate Fasciculus
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