A thermophilic and acid stable family-10 xylanase from the acidophilic fungus Bispora sp. MEY-1

Extremophiles ◽  
2009 ◽  
Vol 13 (5) ◽  
pp. 849-857 ◽  
Author(s):  
Huiying Luo ◽  
Jiang Li ◽  
Jun Yang ◽  
Hui Wang ◽  
Yuhui Yang ◽  
...  
1987 ◽  
Vol 114 (1) ◽  
pp. 18-26 ◽  
Author(s):  
Chohei Shigeno ◽  
Itsuo Yamamoto ◽  
Shegiharu Dokoh ◽  
Megumu Hino ◽  
Jun Aoki ◽  
...  

Abstract. We have partially purified a tumour factor capable of stimulating both bone resorption in vitro and cAMP accumulation in osteoblastic ROS 17/2 cells from three human tumours associated with humoral hypercalcaemia of malignancy. Purification of tumour factor by sequential acid urea extraction, gel filtration and cation-exchange chromatography, reverse-phase high performance liquid chromatography followed by analytical isoelectric focussing provided a basic protein (pI > 9.3) with a molecular weight of approximately 13 000 as a major component of the final preparation which retained both the two bioactivities. Bone resorbing activity and cAMP-increasing activity in purified factor correlated with each other. cAMP-increasing activity of the factor was heat- and acid-stable, but sensitive to alkaline ambient pH. Treatment with trypsin destroyed cAMP-increasing activity of the factor. Synthetic parathyroid hormone (PTH) antagonist, human PTH-(3– 34) completely inhibited the cAMP-increasing activity of the factor. The results suggest that this protein factor, having its effects on both osteoclastic and osteoblastic functions, may be involved in development of enhanced bone resorption in some patients with humoral hypercalcaemia of malignancy.


1984 ◽  
Vol 104 (4_Supplb) ◽  
pp. S91-S92
Author(s):  
G. DAXENBICHLER ◽  
E. H. MOSER
Keyword(s):  
Rat Lung ◽  

Author(s):  
Kenny W.J. Chua ◽  
Jia Huan Liew ◽  
Clare L. Wilkinson ◽  
Amirrudin B. Ahmad ◽  
Heok Hui Tan ◽  
...  

2019 ◽  
Vol 12 (4) ◽  
pp. 171
Author(s):  
Ashis SenGupta ◽  
Moumita Roy

The aim of this article is to obtain a simple and efficient estimator of the index parameter of symmetric stable distribution that holds universally, i.e., over the entire range of the parameter. We appeal to directional statistics on the classical result on wrapping of a distribution in obtaining the wrapped stable family of distributions. The performance of the estimator obtained is better than the existing estimators in the literature in terms of both consistency and efficiency. The estimator is applied to model some real life financial datasets. A mixture of normal and Cauchy distributions is compared with the stable family of distributions when the estimate of the parameter α lies between 1 and 2. A similar approach can be adopted when α (or its estimate) belongs to (0.5,1). In this case, one may compare with a mixture of Laplace and Cauchy distributions. A new measure of goodness of fit is proposed for the above family of distributions.


1967 ◽  
Vol 5 (7) ◽  
pp. 28-28 ◽  

Gastric acid partially destroys benzylpenicillin (penicillin G) and only a small and inconsistent fraction of an oral dose is absorbed. To be certain of its effect the drug must be injected. A number of acid-stable penicillins with the antibacterial range of benzylpenicillin but quite well absorbed from the gut are now available, phenoxymethylpenicillin (penicillin V) for example. In vitro phenoxymethylpenicillin is a little less effective than benzylpenicillin against streptococci1 and considerably less effective against H. influenzae and gonococci. In addition, a higher proportion of phenoxymethylpenicillin than of benzylpenicillin is bound to plasma protein.2 Though controlled trials show that oral benzylpenicillin is as effective as oral phenoxymethylpencillin for most patients with susceptible infections treated outside hospital,3–6 our consultants prefer phenoxymethylpenicillin because absorption is less variable.


2020 ◽  
Author(s):  
Isaac D. Swensen ◽  
Jason Lindo ◽  
Krishna Regmi
Keyword(s):  

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