Patterns of Congenital Lower Urinary Tract Obstructive Uropathy

2003 ◽  
Vol 6 (2) ◽  
pp. 202-203
Author(s):  
Sir Colin Berry
2015 ◽  
Vol 8 (1) ◽  
pp. 124-135 ◽  
Author(s):  
Russell S. Miller

Fetal lower urinary tract obstruction [LUTO] represents a rare, heterogeneous group of uropathies involving mechanical or functional blockage at the bladder outlet of varying severity. While ultrasound is a fair screening tool for the antenatal detection of this condition, it cannot reliably determine the underlying etiology of LUTO presentations. Sonographic assessment of renal appearance and amniotic fluid volume, as well as urinary analyte analysis, are the most useful predictors of preserved renal function in fetal LUTO, although they, too, are limited in their ability to predict outcomes on an individual basis. Animal models suggest that obstructive uropathy likely causes irreparable damage to the renal and urinary collecting system injury early in pregnancy. When LUTO is associated with abnormal amniotic fluid volume, long-standing oligohydramnios may result in lethal pulmonary hypoplasia. Data evaluating the efficacy of vesicoamniotic shunt therapy for the treatment of fetal LUTO are inconclusive. While vesicoamniotic shunting may modify disease lethality by restoring fluid volume, renal and other genitourinary benefits are minimal if not altogether absent, arguably supporting the belief that bladder decompression is being performed after irreversible injury has already been sustained.


2003 ◽  
Vol 6 (2) ◽  
pp. 203-203
Author(s):  
Keith E. Volmar ◽  
Grover M. Hutchins ◽  
Elizabeth J. Perlman ◽  
Michael K. Fritsch

2019 ◽  
Author(s):  
Michael J Barry

Benign prostatic hyperplasia (BPH) is a common cause of morbidity in older men in developed countries. BPH causes lower urinary tract symptoms (LUTS) and occasionally results in such complications as acute urinary retention (AUR), urinary tract infection, and even obstructive uropathy. Although the development of medical treatments has reduced the role of surgery, prostatectomy remains a widely performed procedure. Epidemiology, risk factors, and pathophysiology are discussed. Diagnosis includes clinical features, history, physical examination, and laboratory testing. Management can include watchful waiting, medical treatment, surgery, and minimally invasive treatment. Management of AUR is also addressed.  This review contains 4 figures, 10 tables, and 58 references. Keywords: Benign prostatic hyperplasia, lower urinary tract symptoms, urinary retention, incontinence, alpha blocker, 5α-reductase inhibitor, cystoscopy, transurethral intervention


2019 ◽  
Author(s):  
Michael J Barry

Benign prostatic hyperplasia (BPH) is a common cause of morbidity in older men in developed countries. BPH causes lower urinary tract symptoms (LUTS) and occasionally results in such complications as acute urinary retention (AUR), urinary tract infection, and even obstructive uropathy. Although the development of medical treatments has reduced the role of surgery, prostatectomy remains a widely performed procedure. Epidemiology, risk factors, and pathophysiology are discussed. Diagnosis includes clinical features, history, physical examination, and laboratory testing. Management can include watchful waiting, medical treatment, surgery, and minimally invasive treatment. Management of AUR is also addressed.  This review contains 4 figures, 10 tables, and 58 references. Keywords: Benign prostatic hyperplasia, lower urinary tract symptoms, urinary retention, incontinence, alpha blocker, 5α-reductase inhibitor, cystoscopy, transurethral intervention


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