In Situ Neuroblastoma: An Important Concept Related to the Natural History of Neural Crest Tumors

2005 ◽  
Vol 8 (3) ◽  
pp. 305-306 ◽  
Author(s):  
Hiroyuki Shimada
Keyword(s):  
Natural History ◽  
Neural Crest ◽  
Clinical Significance ◽  
Tumor Biology ◽  
Original Description ◽  
Important Concept ◽  
History Of ◽  
Neural Crest Tumors ◽  
Initial Description

Since the initial description of the entity known as “ in situ neuroblastoma,” thoughts about the origin, fate, and clinical significance of this anatomic finding have influenced the field of neuroectodermal tumor biology. This paper discusses the importance of the original description of in situ neuroblastoma and how the entity fits into contemporary models of neuroblastoma heterogeneity.

P-265 Natural history of untreated endobronchial carcinoma in situ

Lung Cancer ◽  
2005 ◽  
Vol 49 ◽  
pp. S183-S184
Author(s):  
Y. Miller ◽  
R. Keith ◽  
F. Hirsch ◽  
E. Dempsey ◽  
W. Franklin ◽  
...  
Keyword(s):  
Natural History ◽  
Carcinoma In Situ ◽  
History Of

THE NATURAL HISTORY OF BLADDER CARCINOMA IN SITU AFTER INITIAL RESPONSE TO BACILLUS CALMETE-GÚERIN IMMUNOTHERAPY

2008 ◽  
Vol 179 (4S) ◽  
pp. 615-615 ◽  
Author(s):  
Ofer N Gofrit ◽  
Dov Pode ◽  
Galina Pizov ◽  
Kevin C Zorn ◽  
Ran Katz ◽  
...  
Keyword(s):  
Natural History ◽  
Bladder Carcinoma ◽  
Carcinoma In Situ ◽  
Initial Response ◽  
History Of

A revision of the Neotropical spider genus Oligoxystre Vellard 1924  (Theraphosidae, Ischnocolinae)

Zootaxa ◽  
2007 ◽  
Vol 1555 (1) ◽  
pp. 1-20 ◽  
Author(s):  
JOSÉ PAULO LEITE GUADANUCCI
Keyword(s):  
New Species ◽  
Natural History ◽  
Type Species ◽  
Original Description ◽  
Type Specimen ◽  
Additional Material ◽  
History Of

The genus Oligoxystre Vellard 1924 is revised. Pseudoligoxystre Vol 2001 is synonymized with Oligoxystre and its typespecies, P. bolivianum Vol 2001, is considered valid. The type-specimen of Oligoxystre auratum Vellard 1924, type-species by original designation, is considered lost. No additional material matching the original description was found and therefore the species is diagnosed from the original description. Four new species, all from Brazil, are also described: O. caatinga, O. dominguense, O. tucuruiense, and O. rufoniger. Data on natural history of O. bolivianum from field and captivity observations are presented. The genus Cenobiopelma Mello-Leitão & Arlé 1934 ) is based upon Cenobiopelma mimeticum Mello-Leitão & Arlé 1934 for which no type was ever designated and hence both are considered nomina nuda.

scholarly journals Modeling the natural history of ductal carcinoma in situ based on population data

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Sarocha Chootipongchaivat ◽  
Nicolien T. van Ravesteyn ◽  
Xiaoxue Li ◽  
Hui Huang ◽  
Harald Weedon-Fekjær ◽  
...  
Keyword(s):  
Natural History ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Population Data ◽  
History Of

The natural history of ductal carcinoma in situ of the breast: a review

2005 ◽  
Vol 97 (2) ◽  
pp. 135-144 ◽  
Author(s):  
Bircan Erbas ◽  
Elena Provenzano ◽  
Jane Armes ◽  
Dorota Gertig
Keyword(s):  
Natural History ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
History Of

scholarly journals Novel Therapies in Glioblastoma

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
James Perry ◽  
Masahiko Okamoto ◽  
Michael Guiou ◽  
Katsuyuki Shirai ◽  
Allison Errett ◽  
...  
Keyword(s):  
Natural History ◽  
Molecular Biology ◽  
Targeted Therapies ◽  
Conventional Treatment ◽  
Tumor Biology ◽  
Treatment Resistance ◽  
Novel Therapies ◽  
History Of Disease ◽  
History Of ◽  
Poor Outcomes

Conventional treatment of glioblastoma has advanced only incrementally in the last 30 years and still yields poor outcomes. The current strategy of surgery, radiation, and chemotherapy has increased median survival to approximately 15 months. With the advent of molecular biology and consequent improved understanding of basic tumor biology, targeted therapies have become cornerstones for cancer treatment. Many pathways (RTKs, PI3K/AKT/mTOR, angiogenesis, etc.) have been identified in GBM as playing major roles in tumorigenesis, treatment resistance, or natural history of disease. Despite the growing understanding of the complex networks regulating GBM tumors, many targeted therapies have fallen short of expectations. In this paper, we will discuss novel therapies and the successes and failures that have occurred. One clear message is that monotherapies yield minor results, likely due to functionally redundant pathways. A better understanding of underlying tumor biology may yield insights into optimal targeting strategies which could improve the overall therapeutic ratio of conventional treatments.

Clinical Significance, Prevalence, and Natural History of Thrombocytopenia in Pregnancy-Induced Hypertension

1989 ◽  
Vol 6 (01) ◽  
pp. 32-38 ◽  
Author(s):  
Roberto Romero ◽  
Moshe Mazor ◽  
Charles Lockwood ◽  
Mohamed Emamian ◽  
Kathy Belanger ◽  
...  
Keyword(s):  
Natural History ◽  
Clinical Significance ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
History Of ◽  
In Pregnancy
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