Low-dose imatinib in the treatment of severe systemic sclerosis: a case series of six Chinese patients and literature review

2012 ◽  
Vol 31 (9) ◽  
pp. 1395-1400 ◽  
Author(s):  
Li Guo ◽  
Xiao-xiang Chen ◽  
Yue-ying Gu ◽  
He-jian Zou ◽  
Shuang Ye
Keyword(s):  
Systemic Sclerosis ◽  
Literature Review ◽  
Low Dose ◽  
Case Series ◽  
Chinese Patients

scholarly journals Anti-cancer therapy related hand-foot syndrome in patients with systemic sclerosis: Case series and literature review

2020 ◽  
Vol 1 ◽  
pp. 100021
Author(s):  
Madison Grinnell ◽  
Kerri E. Rieger ◽  
Tamiko R. Katsumoto ◽  
Bernice Y. Kwong ◽  
Lisa C. Zaba
Keyword(s):  
Systemic Sclerosis ◽  
Cancer Therapy ◽  
Literature Review ◽  
Case Series ◽  
Anti Cancer ◽  
Hand Foot Syndrome

scholarly journals Low-Dose Naltrexone for Pruritus in Systemic Sclerosis

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Tracy Frech ◽  
Kirsten Novak ◽  
Monica P. Revelo ◽  
Maureen Murtaugh ◽  
Boaz Markewitz ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Gastrointestinal Tract ◽  
Los Angeles ◽  
Low Dose ◽  
Treatment Options ◽  
Case Series ◽  
Common Symptom ◽  
Naltrexone Hydrochloride ◽  
The University ◽  
Low Dose Naltrexone

Pruritus is a common symptom in systemic sclerosis (SSc), an autoimmune disease which causes fibrosis and vasculopathy in skin, lung, and gastrointestinal tract (GIT). Unfortunately, pruritus has limited treatment options in this disease. Pilot trials of low-dose naltrexone hydrochloride (LDN) for pruritus, pain, and quality of life (QOL) in other GIT diseases have been successful. In this case series we report three patients that had significant improvement in pruritus and total GIT symptoms as measured by the 10-point faces scale and the University of California Los Angeles Scleroderma Clinical Trials Consortium Gastrointestinal Tract 2.0 (UCLA SCTC GIT 2.0) questionnaire. This small case series suggests LDN may be an effective, highly tolerable, and inexpensive treatment for pruritus and GIT symptoms in SSc.

scholarly journals Low dose ketamine infusion for pediatric hematology/oncology patients: case series and literature review

2020 ◽  
Author(s):  
Helena Yu ◽  
Allen Chen ◽  
Eric Chen ◽  
L. Stephen Long ◽  
Anurag Agrawal
Keyword(s):  
Literature Review ◽  
Low Dose ◽  
Case Series ◽  
Oncology Patients ◽  
Ketamine Infusion ◽  
Pediatric Hematology

Pseudotumoral calcinosis in systemic sclerosis: Data from systematic literature review and case series from two referral centres

2020 ◽  
Vol 50 (6) ◽  
pp. 1339-1347 ◽  
Author(s):  
Elisabetta Zanatta ◽  
Marie Desportes ◽  
Huy Hoang Do ◽  
Jérôme Avouac ◽  
Andrea Doria ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Case Series

Infrapopliteal Arterial Pseudoaneurysm Development Secondary to Blunt Trauma: Case Series and Literature Review

2020 ◽  
Vol 54 (4) ◽  
pp. 367-374
Author(s):  
Matthew T. Chrencik ◽  
Brian Caraballo ◽  
John Yokemick ◽  
Peter J. Pappas ◽  
Brajesh K. Lal ◽  
...  
Keyword(s):  
Literature Review ◽  
Blunt Trauma ◽  
Case Series ◽  
Duplex Ultrasound ◽  
Endovascular Coiling ◽  
Skeletal Trauma ◽  
Delay In Diagnosis ◽  
Tibial Arteries ◽  
Pulsatile Mass ◽  
Orthopedic Injuries

Objectives: Infrapopliteal arterial pseudoaneurysms (IAP) following blunt trauma with associated orthopedic injuries are uncommon, often present in a delayed fashion, and encompass a diagnostic and therapeutic dilemma. Herein, we present a series of IAPs that were diagnosed following blunt trauma and their management. Methods: Case series consisting of 3 patients and a review of the international literature. Results: Our case series included 3 patients presenting with IAPs following blunt trauma with associated orthopedic injuries. They were all identified in a delayed manner (>3 weeks) after the orthopedic injuries were treated. All patients presented with pain and a pulsatile mass while one concurrently had neurologic deficits. The pseudoaneurysms were diagnosed by duplex ultrasound and confirmed by angiography to be originating from the tibioperoneal trunk, anterior tibial, and posterior tibial arteries respectively. Two patients were treated with surgical excision. Of these, one required an arterial bypass procedure while the other underwent direct ligation only. The third patient was treated by endovascular coiling. A literature review from 1950 to the present found 51 reported cases of IAP resulting from blunt trauma. Ninety percent of trauma-related infrapopliteal injuries occurred in men with a mean delay in diagnosis of 5.6 months (median 1.8 months) after injury. Since 1950, management has shifted from primarily ligation to incorporating minimally invasive endovascular techniques when appropriate. Conclusions: Infrapopliteal artery pseudoaneurysms are rare following blunt skeletal trauma. A delay in diagnosis often occurs and can result in major morbidity and extensive surgical intervention. We recommend a high index of suspicion and a thorough vascular examination in patients with lower extremity skeletal trauma to help identify and treat these injuries early and effectively.

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