Species distribution and in vitro antifungal susceptibility profiles of yeast isolates from invasive infections during a Portuguese multicenter survey

2014 ◽  
Vol 33 (12) ◽  
pp. 2241-2247 ◽  
Author(s):  
I. Faria-Ramos ◽  
J. Neves-Maia ◽  
E. Ricardo ◽  
J. Santos-Antunes ◽  
A. T. Silva ◽  
...  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Maxime Moniot ◽  
Rose-Anne Lavergne ◽  
Thomas Morel ◽  
Romain Guieze ◽  
Florent Morio ◽  
...  

Abstract Background Filamentous basidiomycetes are mainly considered to be respiratory tract colonizers but the clinical significance of their isolation in a specimen is debatable. Hormographiella aspergillata was first reported as a human pathogen in 1971. We discuss the role of this mold as a pathogen or colonizer and give an update on diagnostic tools and in vitro antifungal susceptibility. Case presentation We identified three cases of H. aspergillata with respiratory symptoms in a short period of time. One invasive infection and two colonizations were diagnosed. Culture supernatants showed that H. aspergillata can produce galactomannan and β-D-glucan but not glucuronoxylomannan. For the first time, isavuconazole susceptibility was determined and high minimum inhibitory concentrations (MICs) were found. Liposomal amphotericin B and voriconazole have the lowest MICs. Conclusion To date, 22 invasive infections involving H. aspergillata have been reported. On isolation of H. aspergillata, its pathogenic potential in clinical settings can be tricky. Molecular identification and antifungal susceptibility testing are essential considering high resistance against several antifungal therapies.


2021 ◽  
Vol 7 (4) ◽  
pp. 347-356
Author(s):  
Hussain Yahaya Ungo-kore ◽  
Joseph Olorunmola Ehinmidu ◽  
Josiah Ademola Onaolapo ◽  
Olayeni Stephen Olonitola ◽  
◽  
...  

2016 ◽  
Vol 61 (2) ◽  
Author(s):  
Shuwen Deng ◽  
Saham Ansari ◽  
Macit Ilkit ◽  
Haleh Rafati ◽  
Mohammad T. Hedayati ◽  
...  

ABSTRACT Trichophyton schoenleinii is an anthropophilic dermatophyte mainly causing tinea favosa of the scalp in certain regions of the world, especially Africa and Asia. We investigated the in vitro susceptibilities of 55 T. schoenleinii isolates collected over the last 30 years from Iran, Turkey, and China to 12 antifungals using the CLSI broth microdilution method. Our results revealed that terbinafine and ketoconazole were the most potent antifungal agents among those tested, independently of the geographic regions where strains were isolated.


2008 ◽  
Vol 52 (7) ◽  
pp. 2683-2685 ◽  
Author(s):  
Anna Maria Tortorano ◽  
Anna Prigitano ◽  
Giovanna Dho ◽  
Maria Carmela Esposto ◽  
Claudia Gianni ◽  
...  

ABSTRACT Fusarium isolates from 75 Italian patients were identified by molecular methods, and their susceptibilities to antifungals were tested in vitro. Fusarium verticillioides was the species most frequently isolated from deep-seated infections, and F. solani was the species most frequently isolated from superficial infections. F. solani isolates showed high azole MICs, while F. verticillioides isolates showed low posaconazole MICs.


2016 ◽  
Vol 129 (10) ◽  
pp. 1161-1165 ◽  
Author(s):  
Feng-Juan Wang ◽  
Dai Zhang ◽  
Zhao-Hui Liu ◽  
Wen-Xiang Wu ◽  
Hui-Hui Bai ◽  
...  

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