Irradiation with a red light-emitting diode enhances the proliferation of stem cells of apical papilla via the ERK5 signalling pathway

2022 ◽  
Author(s):  
Chunxia Shu ◽  
Lan Hou ◽  
Qiang Chen ◽  
Tingting Zhu ◽  
Juan Yang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Light Emitting Diode ◽  
Red Light ◽  
Signalling Pathway ◽  
Light Emitting ◽  
Apical Papilla

The red-light emitting diode irradiation increases proliferation of human bone marrow mesenchymal stem cells preserving their immunophenotype

2021 ◽  
pp. 1-11
Author(s):  
Rafał B. Lewandowski ◽  
Małgorzata Stępińska ◽  
Andrzej Gietka ◽  
Monika Dobrzyńska ◽  
Mariusz P. Łapiński ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Light Emitting Diode ◽  
Red Light ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Light Emitting ◽  
Marrow Mesenchymal Stem Cells

scholarly journals Lightwave-reinforced stem cells with enhanced wound healing efficacy

2021 ◽  
Vol 12 ◽  
pp. 204173142110670
Author(s):  
Yu-Jin Kim ◽  
Hye Ran Jeon ◽  
Sung-Won Kim ◽  
Yeong Hwan Kim ◽  
Gwang-Bum Im ◽  
...  
Keyword(s):  
Stem Cells ◽  
Light Emitting Diode ◽  
Red Light ◽  
Cell Therapies ◽  
Light Emitting ◽  
Organic Light Emitting Diode ◽  
Cell Adhesion And Migration ◽  
Cellular Capacity ◽  
And Migration

Comprehensive research has led to significant preclinical outcomes in modified human adipose-derived mesenchymal stem cells (hADSCs). Photobiomodulation (PBM), a technique to enhance the cellular capacity of stem cells, has attracted considerable attention owing to its effectiveness and safety. Here, we suggest a red organic light-emitting diode (OLED)-based PBM strategy to augment the therapeutic efficacy of hADSCs. In vitro assessments revealed that hADSCs basked in red OLED light exhibited enhanced angiogenesis, cell adhesion, and migration compared to naïve hADSCs. We demonstrated that the enhancement of cellular capacity was due to an increased level of intracellular reactive oxygen species. Furthermore, accelerated healing and regulated inflammatory response was observed in mice transplanted with red light-basked hADSCs. Overall, our findings suggest that OLED-based PBM may be an easily accessible and attractive approach for tissue regeneration that can be applied to various clinical stem cell therapies.

Irradiation with blue light-emitting diode enhances osteogenic differentiation of stem cells from the apical papilla

2020 ◽  
Vol 35 (9) ◽  
pp. 1981-1988
Author(s):  
Yaoyao Yang ◽  
Tingting Zhu ◽  
Yan Wu ◽  
Chunxia Shu ◽  
Qiang Chen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Osteogenic Differentiation ◽  
Blue Light ◽  
Light Emitting Diode ◽  
Light Emitting ◽  
Apical Papilla
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