scholarly journals Multilayers and poly(allylamine hydrochloride)-graft-poly(ethylene glycol) modified bovine serum albumin nanoparticles: Improved stability and pH-responsive drug delivery

2012 ◽  
Vol 30 (5) ◽  
pp. 719-726 ◽  
Author(s):  
Li-li Xie ◽  
Wei-jun Tong ◽  
Jian-quan Xu ◽  
Chang-you Gao
Keyword(s):  
Drug Delivery ◽  
Bovine Serum Albumin ◽  
Ethylene Glycol ◽  
Bovine Serum ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Albumin Nanoparticles ◽  
Improved Stability ◽  
Allylamine Hydrochloride ◽  
Poly Ethylene

A Tunable pH-Responsive Nanomaterials for Cancer Delivery

2013 ◽  
Vol 750-752 ◽  
pp. 1476-1479 ◽  
Author(s):  
Bin Liu ◽  
Guan Hui Gao ◽  
Peng Liu ◽  
Hu Qiang Yi ◽  
Wei Wei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Potential Application ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Positive Potential ◽  
Ph Values ◽  
Drugs In Blood ◽  
Poly Ethylene

In this paper, we successfully designed a pH-responsive micelles based on hybrid polypeptide copolymers of poly (L-lysine-4-Azepan-1-yl-butyric)-b-poly (ethylene glycol)-b-poly (L-lysine-Diisopropylamide)-b-poly (L-leucine) (PLL(A)-PEG-PLL(B)-PLLeu) for efficient drug delivery. This pH-responsive nanoparticles were able to response to different pH values (pH=6.8 and 5.5). In vitro, these nanoparticles exhibited a stable and evenly distributed approximately 51 nm, a slightly positive potential about 10.3 mv at pH 7.4, which were crucial for the circulation of drugs in blood. While size and potential were about 130 nm and 34.7 mv at pH 6.8, which were good for drugs in membrane. Furthermore, the loading capability of DOX was up to 11.3%, and the pH-responsive release efficiency reached to 68.3% at pH 5.5. The results indicated that these micelles had huge potential application in cancer delivery.

Tryptophan 2,3-dioxygenase-like activity of manganese (III) porphyrin bound to bovine serum albumin modified with poly(ethylene glycol)

1993 ◽  
Vol 81 (2) ◽  
pp. L13-L17 ◽  
Author(s):  
Takashi Sagawa ◽  
Hitoshi Ishida ◽  
Kenji Urabe ◽  
Kohji Yoshinaga ◽  
Katsutoshi Ohkubo
Keyword(s):  
Bovine Serum Albumin ◽  
Ethylene Glycol ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

scholarly journals pH-Responsive Poly(Ethylene Glycol)-block-Polylactide Micelles for Tumor-Targeted Drug Delivery

2017 ◽  
Vol 18 (9) ◽  
pp. 2711-2722 ◽  
Author(s):  
Lin Xiao ◽  
Lixia Huang ◽  
Firmin Moingeon ◽  
Mario Gauthier ◽  
Guang Yang
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Targeted Drug Delivery ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Targeted Drug ◽  
Poly Ethylene

Complex Formation of Bovine Serum Albumin with a Poly(ethylene glycol) Lipid Conjugate

2007 ◽  
Vol 8 (7) ◽  
pp. 2244-2249 ◽  
Author(s):  
Valeria Castelletto ◽  
Marta Krysmann ◽  
Antonios Kelarakis ◽  
Paula Jauregi
Keyword(s):  
Bovine Serum Albumin ◽  
Complex Formation ◽  
Ethylene Glycol ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
Lipid Conjugate
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