scholarly journals Histologic purity of signet ring cell carcinoma is a favorable risk factor for lymph node metastasis in poorly cohesive, submucosa-invasive early gastric carcinoma

2016 ◽  
Vol 20 (4) ◽  
pp. 583-590 ◽  
Author(s):  
Yon Hee Kim ◽  
Ji Hye Park ◽  
Cheol Keun Park ◽  
Jie-Hyun Kim ◽  
Sang Kil Lee ◽  
...  
Keyword(s):  
Risk Factor ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Gastric Carcinoma ◽  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Node Metastasis ◽  
Signet Ring ◽  
Ring Cell

scholarly journals A nomogram for predicting the likelihood of lymph node metastasis in early gastric signet ring cell carcinoma

Medicine ◽  
2016 ◽  
Vol 95 (46) ◽  
pp. e5393 ◽  
Author(s):  
Chun Guang Guo ◽  
Yan Jia Chen ◽  
Hu Ren ◽  
Hong Zhou ◽  
Ju Fang Shi ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Node Metastasis ◽  
Signet Ring ◽  
Ring Cell

Sa1665 The Incidence of Lymph Node Metastasis in Cases of Early Gastric Signet Ring Cell Carcinoma is As Low As Early Gastric Differentiated Adenocarcinoma

2012 ◽  
Vol 75 (4) ◽  
pp. AB238
Author(s):  
Sang Heon Lee ◽  
Sam Ryong Jee ◽  
Ji Hyun Kim ◽  
Kyung Sun Ok ◽  
Jung Sik Choi ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Node Metastasis ◽  
Signet Ring ◽  
Ring Cell

scholarly journals A Case of Primary Signet-ring Cell Carcinoma of the Lung Whose Neck Lymph Node Metastasis Progressed Rapidly

Haigan ◽  
2011 ◽  
Vol 51 (1) ◽  
pp. 11-15
Author(s):  
Yoshitaka Zenke ◽  
Hiroshi Igei ◽  
Eri Inoue ◽  
Takao Hanehira ◽  
Yu Enomoto ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Neck Lymph Node ◽  
Node Metastasis ◽  
Signet Ring ◽  
Neck Lymph Node Metastasis ◽  
Ring Cell

Lymph node metastasis in early signet ring cell carcinoma: Endoscopic mucosal resection

2008 ◽  
Vol 20 (4) ◽  
pp. 274-278
Author(s):  
Hua Li ◽  
Ping Lu ◽  
Jing Zhang ◽  
Hui-mian Xu ◽  
Shu-bao Wang ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Endoscopic Mucosal Resection ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Node Metastasis ◽  
Mucosal Resection ◽  
Signet Ring ◽  
Ring Cell

Matrilsin expression is a useful marker of submucosal invasion and lymph node metastasis in early stage signet ring cell carcinoma of the stomach

2006 ◽  
Vol 93 (6) ◽  
pp. 491-497 ◽  
Author(s):  
Ryuusuke Aihara ◽  
Erito Mochiki ◽  
Yoichi Kamiyama ◽  
Tetsuro Ohno ◽  
Takayuki Asao ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Early Stage ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Carcinoma Of The Stomach ◽  
Node Metastasis ◽  
Signet Ring ◽  
Ring Cell

Risk Factors for Lymph Node Metastasis in Early Gastric Cancer with Signet Ring Cell Carcinoma

2015 ◽  
Vol 19 (11) ◽  
pp. 1958-1965 ◽  
Author(s):  
Chun Guang Guo ◽  
Dong Bing Zhao ◽  
Qian Liu ◽  
Zhi Xiang Zhou ◽  
Ping Zhao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Early Gastric Cancer ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Node Metastasis ◽  
Signet Ring ◽  
Ring Cell

scholarly journals The value of lymph node ratio and total number of lymph nodes examined for resected pancreatic signet ring cell carcinoma: a retrospective cohort study

2020 ◽  
Author(s):  
Chao Ren ◽  
Feng Xue ◽  
Yinying Wu ◽  
Zheng Wang
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Lymph Node Ratio ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Node Metastasis ◽  
Signet Ring ◽  
Node Ratio ◽  
Ring Cell

Abstract Background—Pancreatic signet ring cell carcinoma (SRCC) was an exceedingly rare histological subtype of pancreatic cancer. Previous studies focused on the trends of incidence and independent predictors of pancreatic SRCC. Our objectives of the study was to analyze the prognostic value of lymph node ratio (LNR) and explore the minimal number of lymph nodes examined to accurately evaluate the N stage in resected pancreatic signet ring cell carcinoma.Method—The data diagnosed from January 1, 1990 to December 31, 2016 constituted the study cohort from the Surveillance, Epidemiology, and End Results(SEER) registry. We calculated overall survival (OS) of these patients using Kaplan–Meier analysis and Cox proportional hazards model and used receiver-operating characteristic curve (ROC) analysis to investigate the discriminatory ability of the total number of lymph nodes examined(TNLE) relative to whether lymph node metastasis.Results—The median number of lymph nodes examined among 120 patients of resected pancreatic SRCC was 14 (interquartile range, 6.25 to 20.0).According to the univariate analysis of overall survival(OS) result, age, grade, chemotherapy, LNR and TNLE were significantly different(P<0.05).Multivariate survival analysis showed that LNR and grade were the independent prognostic indicators after pancreatic SRCC resection for OS. TNLE ≥ 8 showed the highest discriminatory power to evaluate whether the lymph node metastasis (AUC 0.656, 95%CI 0.564-0.741, Youden index 0.2533, sensitivity 78.67%, specificity 46.67%, P= 0.003)Conclusion—Our study indicated that LNR was a valuable independent prognostic factor for resected pancreatic SRCC. Regional lymphadenectomy of at least 8 lymph nodes was necessary to stage patients accurately. Enough number lymph nodes examined was necessary for the clinicians to accurately predict the significance of LNR in resected pancreatic SRCC.

scholarly journals Prognostic Analysis of Primary Breast Signet Ring Cell Carcinoma and Mucinous Breast Adenocarcinoma: A SEER Population-Based Study

2021 ◽  
Vol 11 ◽  
Author(s):  
Song Wang ◽  
Yiyuan Zhang ◽  
Fangxu Yin ◽  
Xiangsheng Zhang ◽  
Zhenlin Yang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Clinicopathological Features ◽  
Breast Adenocarcinoma ◽  
Node Metastasis ◽  
Signet Ring ◽  
Ring Cell

BackgroundPrimary breast signet ring cell carcinoma (SRCC) is a rare type of breast cancer with typical morphological characteristics, high aggressiveness, and poor prognosis. SRCC is different from mucinous breast adenocarcinoma (MBC). However, only a few studies have explored the clinicopathological features and prognosis of SRCC and MBC.MethodsData retrieved from the Surveillance, Epidemiology, and End-Results (SEER) database (2004–2015) were used to explore the prognostic effect of clinicopathological features and treatment modalities on survival outcomes of SRCC and MBC patients. Kaplan–Meier plot analysis, multivariate Cox proportional risk model, propensity score matching (PSM), and subgroup analysis were performed.ResultsA total of 167 patients with SRCC and 11,648 patients with MBC were included in the study. SRCC patients exhibited higher histological grade (p &lt; 0.001), larger tumor volume (p &lt; 0.001), higher rate of lymph node metastasis (p &lt; 0.001), and higher frequency of distal metastasis (p &lt; 0.001) compared with MBC patients. Cox proportional hazards regression analysis showed that SRCC patients had lower overall survival (OS) and breast cancer-specific survival (BCSS) compared with MBC patients. Subgroup survival analysis showed that the SRCC patients had lower OS and BCSS in subgroups including younger than 60 years old, white race, married, without chemotherapy, and received radiotherapy compared with the MBC patients in these subgroups. In addition, the SRCC patients had lower BCSS in subgroups including other races (including Asian or Pacific Islander and American Indian/Alaska Native), without surgery, and lymph node metastasis.ConclusionThe findings showed that primary breast SRCC patients have unique clinical characteristics and worse prognosis compared with MBC patients. Notably, different treatment methods resulted in different prognosis for SRCC and MBC types; therefore, SRCC patients should be distinguished from MBC patients to improve efficacy of treatment.

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