ChronoSphere: a graph-based EMF model repository for IT landscape models

AbstractDiffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain tumor and the leading cause of brain tumor–related death in children. As several clinical trials over the past few decades have led to no significant improvements in outcome, the current standard of care remains fractionated focal radiation. Due to the recent increase in stereotactic biopsies, tumor tissue availabilities have enabled our advancement of the genomic and molecular characterization of this lethal cancer. Several groups have identified key histone gene mutations, genetic drivers, and methylation changes in DIPG, providing us with new insights into DIPG tumorigenesis. Subsequently, there has been increased development of in vitro and in vivo models of DIPG which have the capacity to unveil novel therapies and strategies for drug delivery. This review outlines the clinical characteristics, genetic landscape, models, and current treatments and hopes to shed light on novel therapeutic avenues and challenges that remain.

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Forest landscape models, a tool for understanding the effect of the large-scale and long-term landscape processes

Forest Ecology and Management ◽

10.1016/j.foreco.2007.09.069 ◽

2008 ◽

Vol 254 (3) ◽

pp. 371-374 ◽

Cited By ~ 18

Author(s):

Hong S. He ◽

Robert E. Keane ◽

Louis R. Iverson

Keyword(s):

Large Scale ◽

Forest Landscape ◽

Landscape Models ◽

Landscape Processes

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Multi-model comparison on the effects of climate change on tree species in the eastern U.S.: results from an enhanced niche model and process-based ecosystem and landscape models

Landscape Ecology ◽

10.1007/s10980-016-0404-8 ◽

2016 ◽

Vol 32 (7) ◽

pp. 1327-1346 ◽

Cited By ~ 30

Author(s):

Louis R. Iverson ◽

Frank R. Thompson ◽

Stephen Matthews ◽

Matthew Peters ◽

Anantha Prasad ◽

...

Keyword(s):

Climate Change ◽

Tree Species ◽

Model Comparison ◽

Niche Model ◽

Landscape Models

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Landscape Models of Complex Change

The Oxford Handbook of Organizational Change and Innovation ◽

10.1093/oxfordhb/9780198845973.013.21 ◽

2021 ◽

pp. 554-580

Author(s):

Daniel Albert ◽

Martin Ganco

Keyword(s):

Organizational Change ◽

Future Research ◽

Research Directions ◽

Traditional Form ◽

Nk Model ◽

Complex Change ◽

Landscape Models ◽

Recent Advances ◽

Complex Landscape ◽

Future Research Directions

This chapter reviews recent advances in the NK modeling literature conceptualizing organizational change and innovation as a search over a complex landscape. It discusses both strengths and limitations of this perspective and delineates potential for future research directions. The key argument is that the NK model in its traditional form may be exhausting the theoretical insights that it can provide to the field. However, substantial modifications and extensions of the NK model or new classes of landscape models may provide fresh perspectives. Specifically, we consider the modeling efforts that endogenize the landscape construction as the next frontier in this literature. We also discuss several recent studies that incorporate various extensions of the NK model and allow for agent-driven changes to the landscape.

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The environmental navigation using geometric virtual reality

Advances in Mechanical Engineering ◽

10.1177/1687814018783636 ◽

2018 ◽

Vol 10 (6) ◽

pp. 168781401878363 ◽

Cited By ~ 1

Author(s):

Nien-Tsu Hu ◽

Pu-Sheng Tsai ◽

Ter-Feng Wu ◽

Jen-Yang Chen ◽

Lin Lee

Keyword(s):

Virtual Reality ◽

System Architecture ◽

Three Dimensional ◽

Wearable Devices ◽

Wireless Transmission ◽

Wearable Electronics ◽

Virtual Reality Environment ◽

Landscape Models ◽

Three Dimensional Models ◽

Animation Software

This article explores the construction of a geometric virtual reality platform for the environmental navigation. Non-panoramic photos and wearable electronics with Bluetooth wireless transmission functions are used to combine the user’s actions with the virtual reality environment in a first-person virtual reality platform. The 3ds Max animation software is used to create three-dimensional models of real buildings. These models are combined with the landscape models in Unity3d to create a virtual campus scene that matches real landscape. The wearable device included an ATMega168 chip as a microcontroller; it was connected to a three-axis accelerometer, a gyroscope, and a Bluetooth transmitter to detect and transmit various movements of the user. Although the development of the mechatronics, software, and engineering involved in the three-dimensional animation are the main objective, we believe that the methods and techniques can be modified for various purposes. After the system architecture was created and the operations of the platform were verified, wearable devices and virtual reality scenes are concluded to be able to be used together seamlessly.

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