Hydrodynamic blood plasma separation in microfluidic channels

2009 ◽  
Vol 8 (1) ◽  
pp. 105-114 ◽  
Author(s):  
Maïwenn Kersaudy-Kerhoas ◽  
Resham Dhariwal ◽  
Marc P. Y. Desmulliez ◽  
Lionel Jouvet
Keyword(s):  
Blood Plasma ◽  
Microfluidic Channels ◽  
Plasma Separation ◽  
Blood Plasma Separation

Structural Design of Microfluidic Channels for Blood Plasma Separation

2014 ◽  
Vol 14 (10) ◽  
pp. 7419-7426 ◽  
Author(s):  
Jingjing Zhang ◽  
Xueyong Wei ◽  
Xiangdong Xue ◽  
Zhuangde Jiang
Keyword(s):  
Blood Plasma ◽  
Structural Design ◽  
Microfluidic Channels ◽  
Plasma Separation ◽  
Blood Plasma Separation

Biological Fluid Separation in Microfluidic Channels Using Flow Rate Control

2005 ◽  
Author(s):  
Sung Yang ◽  
Akif U¨ndar ◽  
Jeffrey D. Zahn
Keyword(s):  
Blood Plasma ◽  
Real Time ◽  
Microfluidic Device ◽  
Numerical Study ◽  
Biological Fluid ◽  
Microfluidic Channels ◽  
Defibrinated Sheep Blood ◽  
Plasma Separation ◽  
Study Results ◽  
Blood Plasma Separation

A microfluidic device for continuous, real time blood plasma separation is introduced. This device is composed of a blood inlet, a purified plasma outlet, and a concentrated blood cell outlet. It is designed to separate blood plasma from an initial blood sample of up to 45 % hematocrit (Hct). The microfluidic device is designed and analyzed using an analogous electrical circuit, analytical and numerical studies. The numerical study results show that 27 % and 25 % of plasma volume can be separated from a total inlet blood volume of 45 % and 39 % hematocrit, respectively. The functionality of this device was demonstrated using defibrinated sheep blood (Hct=36 %). During 2 hrs. of continuous blood infusion through the device, all the blood cells traveled through the device toward the concentrated blood outlet while only the plasma flowed towards the plasma outlet without any clogging or lysis of cells. The experimentally measured plasma skimming volume was about 33 % for a 36 % inlet hematocrit. Due to the device’s simple structure and control mechanism, this microdevice is expected to be used for highly efficient continuous, real time cell-free blood plasma separation device.

A Circular Gradient-Width Crossflow Microfluidic Platform for High-Efficiency Blood Plasma Separation

2021 ◽  
pp. 131180
Author(s):  
Han Zhang ◽  
Kanjirakat Anoop ◽  
Can Huang ◽  
Reza Sadr ◽  
Rohit Gupte ◽  
...  
Keyword(s):  
Blood Plasma ◽  
High Efficiency ◽  
Microfluidic Platform ◽  
Plasma Separation ◽  
Blood Plasma Separation

Fast blood plasma separation device for point-of-care applications

Talanta ◽  
2018 ◽  
Vol 183 ◽  
pp. 55-60 ◽  
Author(s):  
Pavol Ďurč ◽  
František Foret ◽  
Petr Kubáň
Keyword(s):  
Blood Plasma ◽  
Point Of Care ◽  
Separation Device ◽  
Plasma Separation ◽  
Blood Plasma Separation

Ultrahigh throughput beehive‐like device for blood plasma separation

2020 ◽  
Vol 41 (24) ◽  
pp. 2136-2143
Author(s):  
Fengtao Jiang ◽  
Nan Xiang ◽  
Zhonghua Ni
Keyword(s):  
Blood Plasma ◽  
Plasma Separation ◽  
Blood Plasma Separation

scholarly journals Construction of Membrane Sieves Using Stoichiometric and Stress-Reduced Si3N4/SiO2/Si3N4Multilayer Films and Their Applications in Blood Plasma Separation

ETRI Journal ◽  
2012 ◽  
Vol 34 (2) ◽  
pp. 226-234 ◽  
Author(s):  
Dae-Sik Lee ◽  
Yo Han Choi ◽  
Yong Duk Han ◽  
Hyun C. Yoon ◽  
Shuichi Shoji ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Plasma Separation ◽  
Blood Plasma Separation ◽  
In Blood Plasma

A passive two-way microfluidic device for low volume blood-plasma separation

2019 ◽  
Vol 209 ◽  
pp. 28-34 ◽  
Author(s):  
L. Spigarelli ◽  
V. Bertana ◽  
D. Marchisio ◽  
L. Scaltrito ◽  
S. Ferrero ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Microfluidic Device ◽  
Plasma Separation ◽  
Volume Blood ◽  
Low Volume ◽  
Blood Plasma Separation
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