The Specifics of Adrenergic Innervation of Lymph Nodes from Different Body Regions in Young, Mature, and Old Animals

2021 ◽  
Vol 170 (3) ◽  
pp. 283-287
Author(s):  
G. A. Demchenko ◽  
S. N. Abdreshov ◽  
N. A. Akhmetbaeva ◽  
E. K. Makashev ◽  
B. A. Nurmakhanova ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Adrenergic Innervation ◽  
Body Regions

The specifics of adrenergic innervation of lymph nodes from different body regions in young, mature and old animals

2020 ◽  
Vol 170 (9) ◽  
pp. 268-273
Author(s):  
G. A. Demchenko ◽  
◽  
S. N. Abdreshov ◽  
N. A. Akhmetbayeva ◽  
E. K. Makashev ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Adrenergic Innervation ◽  
Body Regions

scholarly journals ADRENERGIC INNERVATION OF LYMPHATIC NODES FROM VARIOUS BODY REGIONS IN YOUNG AND MATURE ANIMALS

REPORTS ◽  
2018 ◽  
Vol 6 (322) ◽  
pp. 40-44
Author(s):  
G. A. Demchenko ◽  
◽  
N. A. Akhmetbayeva ◽  
Keyword(s):  
Adrenergic Innervation ◽  
Body Regions

scholarly journals Adrenergic innervation in reactive human lymph nodes

1999 ◽  
Vol 194 (1) ◽  
pp. 143-146 ◽  
Author(s):  
A. L. PANUNCIO ◽  
S. DE LA PENA ◽  
G. GUALCO ◽  
N. REISSENWEBER
Keyword(s):  
Lymph Nodes ◽  
Adrenergic Innervation

scholarly journals Lymphodynamics and adrenergic innervation of the kidney and renal lymph nodes in toxic hepatitis

2020 ◽  
Vol 19 (3) ◽  
pp. 73-79
Author(s):  
S. N. Abdreshov ◽  
A. O. Balkhybekova ◽  
G. A. Demchenko ◽  
G. I. Lobov
Keyword(s):  
Lymph Nodes ◽  
Toxic Hepatitis ◽  
Adrenergic Innervation ◽  
Renal Lymph

scholarly journals LAWS OF THE MORPHOLOGY OF THE VISCERAL LYMPH NODES, TAKING LYMPH FROM VARIOUS ORGANS AND BODY REGIONS

2018 ◽  
Vol 65 (1) ◽  
pp. 26-28
Author(s):  
A.I. Krayushkin ◽  
◽  
A.I. Perepelkin ◽  
V.V. Sivik ◽  
E.A. Zagorodneva ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Body Regions

Genomic characterization of metastatic lung cancers.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 9584-9584
Author(s):  
Hui Yu ◽  
Hua Bao ◽  
Yulin Wei ◽  
Min Wu ◽  
Shuyu Wu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Nodes ◽  
Egfr Mutations ◽  
Metastatic Lung Cancer ◽  
Mutational Signatures ◽  
Primary Tumors ◽  
Body Regions ◽  
Metastatic Lung ◽  
Organ Specific ◽  
The Brain

9584 Background: Lung carcinomas are most often diagnosed at stage IV, with metastases, which contribute to 90% of deaths of patients. Enormous efforts have been made in previous studies in seek of underlying mechanisms and treatments that prevent or cure metastases. However, few comprehensive conclusions have been drawn on organ-specific genomic landscapes and molecular dependencies of lung cancer metastases, largely due to limited sample sizes. Methods: We employed massive targeted next generation sequencing (NGS) with a panel covering 425 cancer-related genes on 10409 samples from 8619 patients with lung cancer, including 8479 from primary tumors and 1930 from metastases to the brain, liver, pleura, bones, and lymph nodes. We investigated single nucleotide variants (SNVs), copy number variants (CNVs), structural variations (SVs), mutational signatures, and other genomic characteristics at all primary and metastatic sites. With data of primary-metastatic tumor pairs, we also examined genomic evolutionary patterns. Results: Our data revealed that metastases harbored more instable and complicated genomes. Most SNVs (5/6), CNVs (41/47), and SVs (2/3) that showed significant differences of prevalence between primary tumors (PTs) and metastases (MTs) were MT-enriched. Among them, we identified a novel MT-enriched event, PTK2 amplification (2.33 folds), as well as known ones including mutations of TP53, ARID1A, and BRCA1 (1.23, 1.74, and 2.29 folds) , and amplifications of MYC, RICTOR, and EGFR (2.04, 2.15, and 1.59 folds). In addition, almost all actionable CNV alterations (6/7) showed higher frequencies in MTs. ALK fusions and EGFR mutations, which indicate distinct target therapies, exhibited opposite preference in MTs and PTs, respectively. We also identified MT site-specificity of alterations, such as NF2, TSC2, and LRP1B mutations enriched in the brain, BRAF and GNAS mutations absent in the liver, and APOBEC-associated mutational signatures enriched in lymph nodes. Moreover, we unraveled organ-specific patterns of genomic evolutionary trajectories in metastatic diseases. Conclusions: The genomic profile and evolutionary pattern of metastatic lung cancer differed from that of primary tumors. The identification of site-specific characteristics that may have empowered directional metastasis, such as NF2, TSC2, and LRP1B mutations in the brain and APOBEC-associated mutational signatures in lymph nodes, may guide personalized disease management, design of clinical trials, and/or discovery of therapeutic targets for metastatic lung cancer at different body regions.

Adrenergic Innervation of the thyroid Gland, Blood and Lymph Vessels, and Lymph Nodes in Hypothyroidism

2019 ◽  
Vol 168 (2) ◽  
pp. 295-299 ◽  
Author(s):  
S. N. Abdreshov ◽  
N. A. Akhmetbaeva ◽  
G. K. Atanbaeva ◽  
A. T. Mamataeva ◽  
U. B. Nauryzbai
Keyword(s):  
Thyroid Gland ◽  
Lymph Nodes ◽  
Adrenergic Innervation ◽  
Lymph Vessels

Condition of Adrenergic Innervation Apparatus of the Thyroid Gland, Blood and Lymph Vessels, and Lymph Nodes during Correction of Hypothyrosis

2021 ◽  
Author(s):  
S. N. Abdreshov ◽  
G. A. Demchenko ◽  
A. T. Mamataeva ◽  
G. K. Atanbaeva ◽  
S. A. Mankibaeva ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Lymph Nodes ◽  
Adrenergic Innervation ◽  
Lymph Vessels

Scanning electron microscopy of freeze-fractured prescapular lymph node of caprine

1984 ◽  
Vol 42 ◽  
pp. 244-245
Author(s):  
O. Faroon ◽  
F. Al-Bagdadi ◽  
T. G. Snider ◽  
C. Titkemeyer
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Lymphatic System ◽  
Three Dimensional ◽  
Meat Products ◽  
The Body ◽  
Morphological Data ◽  
The World ◽  
Cellular Constituent ◽  
Scanning Electron

The lymphatic system is very important in the immunological activities of the body. Clinicians confirm the diagnosis of infectious diseases by palpating the involved cutaneous lymph node for changes in size, heat, and consistency. Clinical pathologists diagnose systemic diseases through biopsies of superficial lymph nodes. In many parts of the world the goat is considered as an important source of milk and meat products.The lymphatic system has been studied extensively. These studies lack precise information on the natural morphology of the lymph nodes and their vascular and cellular constituent. This is due to using improper technique for such studies. A few studies used the SEM, conducted by cutting the lymph node with a blade. The morphological data collected by this method are artificial and do not reflect the normal three dimensional surface of the examined area of the lymph node. SEM has been used to study the lymph vessels and lymph nodes of different animals. No information on the cutaneous lymph nodes of the goat has ever been collected using the scanning electron microscope.

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