Introduction to the Special Issue on Statistical Genetic Methods for Human Complex Traits

2021 ◽  
Author(s):  
David M. Evans ◽  
Sarah E. Medland ◽  
Elizabeth Prom-Wormley
Keyword(s):  
Complex Traits ◽  
Special Issue ◽  
Human Complex

scholarly journals Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

2021 ◽  
Author(s):  
Valentin Hivert ◽  
Julia Sidorenko ◽  
Florian Rohart ◽  
Michael E. Goddard ◽  
Jian Yang ◽  
...  
Keyword(s):  
Complex Traits ◽  
Genetic Variance ◽  
Additive Genetic Variance ◽  
Large Sample ◽  
Human Complex

The role of sex in the genomics of human complex traits

2018 ◽  
Vol 20 (3) ◽  
pp. 173-190 ◽  
Author(s):  
Ekaterina A. Khramtsova ◽  
Lea K. Davis ◽  
Barbara E. Stranger
Keyword(s):  
Complex Traits ◽  
Human Complex

scholarly journals The Y Chromosome: A Complex Locus for Genetic Analyses of Complex Human Traits

Genes ◽  
2020 ◽  
Vol 11 (11) ◽  
pp. 1273
Author(s):  
Katherine Parker ◽  
A. Mesut Erzurumluoglu ◽  
Santiago Rodriguez
Keyword(s):  
Population Genetics ◽  
Genetic Variation ◽  
Y Chromosome ◽  
Complex Traits ◽  
Association Studies ◽  
Epidemiological Studies ◽  
Complex Locus ◽  
Complex Human Traits ◽  
Human Complex ◽  
Human Y Chromosome

The Human Y chromosome (ChrY) has been demonstrated to be a powerful tool for phylogenetics, population genetics, genetic genealogy and forensics. However, the importance of ChrY genetic variation in relation to human complex traits is less clear. In this review, we summarise existing evidence about the inherent complexities of ChrY variation and their use in association studies of human complex traits. We present and discuss the specific particularities of ChrY genetic variation, including Y chromosomal haplogroups, that need to be considered in the design and interpretation of genetic epidemiological studies involving ChrY.

37 CONTRIBUTIONS OF COPY NUMBER VARIANTS TO HUMAN COMPLEX TRAITS

2019 ◽  
Vol 29 ◽  
pp. S79-S80
Author(s):  
Kyoko Watanabe ◽  
Jeanne Savage ◽  
Meaghan McConlogue ◽  
Benjamin Neale ◽  
Danielle Posthuma
Keyword(s):  
Complex Traits ◽  
Copy Number ◽  
Copy Number Variants ◽  
Human Complex

scholarly journals Linking the genetic architecture of cytosine modifications with human complex traits

2014 ◽  
Vol 23 (22) ◽  
pp. 5893-5905 ◽  
Author(s):  
Xu Zhang ◽  
Erika L. Moen ◽  
Cong Liu ◽  
Wenbo Mu ◽  
Eric R. Gamazon ◽  
...  
Keyword(s):  
Complex Traits ◽  
Genetic Architecture ◽  
Human Complex
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