A Nation-Wide Swedish Cohort Study on Early Maternal Age at First Childbirth and Risk for Offspring Deaths, Accidents, and Suicide Attempts

2021 ◽  
Author(s):  
Ayesha C. Sujan ◽  
Lauren M. O’Reilly ◽  
Martin E. Rickert ◽  
Henrik Larsson ◽  
Paul Lichtenstein ◽  
...  
Keyword(s):  
Cohort Study ◽  
Maternal Age ◽  
Suicide Attempts ◽  
Swedish Cohort ◽  
Early Maternal Age

scholarly journals Association of suicide attempts with acne and treatment with isotretinoin: retrospective Swedish cohort study

BMJ ◽  
2010 ◽  
Vol 341 (nov11 1) ◽  
pp. c5812-c5812 ◽  
Author(s):  
A. Sundstrom ◽  
L. Alfredsson ◽  
G. Sjolin-Forsberg ◽  
B. Gerden ◽  
U. Bergman ◽  
...  
Keyword(s):  
Cohort Study ◽  
Suicide Attempts ◽  
Swedish Cohort

scholarly journals Advanced maternal age and adverse pregnancy outcomes: A cohort study

2021 ◽  
Vol 60 (1) ◽  
pp. 119-124
Author(s):  
M. Guarga Montori ◽  
A. Álvarez Martínez ◽  
C. Luna Álvarez ◽  
N. Abadía Cuchí ◽  
P. Mateo Alcalá ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pregnancy Outcomes ◽  
Maternal Age ◽  
Advanced Maternal Age ◽  
Adverse Pregnancy Outcomes ◽  
Adverse Pregnancy

Maternal age at birth and daughter’s fecundability

2021 ◽  
Author(s):  
Olga Basso ◽  
Sydney K Willis ◽  
Elizabeth E Hatch ◽  
Ellen M Mikkelsen ◽  
Kenneth J Rothman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Maternal Age ◽  
Limited Information ◽  
Loss To Follow Up ◽  
Older Mothers ◽  
Registration Number ◽  
The Usa ◽  
Competing Interest

Abstract STUDY QUESTION Do daughters of older mothers have lower fecundability? SUMMARY ANSWER In this cohort study of North American pregnancy planners, there was virtually no association between maternal age ≥35 years and daughters’ fecundability. WHAT IS KNOWN ALREADY Despite suggestive evidence that daughters of older mothers may have lower fertility, only three retrospective studies have examined the association between maternal age and daughter’s fecundability. STUDY DESIGN, SIZE, DURATION Prospective cohort study of 6689 pregnancy planners enrolled between March 2016 and January 2020. PARTICIPANTS/MATERIALS, SETTING, METHODS Pregnancy Study Online (PRESTO) is an ongoing pre-conception cohort study of pregnancy planners (age, 21-45 years) from the USA and Canada. We estimated fecundability ratios (FR) for maternal age at the participant’s birth using multivariable proportional probabilities regression models. MAIN RESULTS AND THE ROLE OF CHANCE Daughters of mothers ≥30 years were less likely to have previous pregnancies (or pregnancy attempts) or risk factors for infertility, although they were more likely to report that their mother had experienced problems conceiving. The proportion of participants with prior unplanned pregnancies, a birth before age 21, ≥3 cycles of attempt at study entry or no follow-up was greater among daughters of mothers <25 years. Compared with maternal age 25–29 years, FRs (95% CI) for maternal age <20, 20–24, 30–34, and ≥35 were 0.72 (0.61, 0.84), 0.92 (0.85, 1.00), 1.08 (1.00, 1.17), and 1.00 (0.89, 1.12), respectively. LIMITATIONS, REASONS FOR CAUTION Although the examined covariates did not meaningfully affect the associations, we had limited information on the participants’ mother. Differences by maternal age in reproductive history, infertility risk factors and loss to follow-up suggest that selection bias may partly explain our results. WIDER IMPLICATIONS OF THE FINDINGS Our finding that maternal age 35 years or older was not associated with daughter’s fecundability is reassuring, considering the trend towards delayed childbirth. However, having been born to a young mother may be a marker of low fecundability among pregnancy planners. STUDY FUNDING/COMPETING INTEREST(S) PRESTO was funded by NICHD Grants (R21-HD072326 and R01-HD086742) and has received in-kind donations from Swiss Precision Diagnostics, FertilityFriend.com, Kindara.com, and Sandstone Diagnostics. Dr Wise is a fibroid consultant for AbbVie, Inc. TRIAL REGISTRATION NUMBER n/a

Intercountry adopted children as young adults--A Swedish cohort study.

2003 ◽  
Vol 73 (2) ◽  
pp. 190-202 ◽  
Author(s):  
Frank Lindblad ◽  
Anders Hjern ◽  
B. Vinnerljung
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Adopted Children ◽  
Swedish Cohort

The effect of advanced maternal age on maternal and neonatal outcomes of placenta previa: A register-based cohort study

2018 ◽  
Vol 227 ◽  
pp. 1-7 ◽  
Author(s):  
Zahra Roustaei ◽  
Katri Vehviläinen-Julkunen ◽  
Tomi-Pekka Tuomainen ◽  
Reeta Lamminpää ◽  
Seppo Heinonen
Keyword(s):  
Cohort Study ◽  
Maternal Age ◽  
Placenta Previa ◽  
Advanced Maternal Age ◽  
Neonatal Outcomes ◽  
Maternal And Neonatal Outcomes

scholarly journals Maternal age at first cesarean delivery related to adverse pregnancy outcomes in a second cesarean delivery: a multicenter, historical, cross-sectional cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shilei Bi ◽  
Lizi Zhang ◽  
Jingsi Chen ◽  
Minshan Huang ◽  
Lijun Huang ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cohort Study ◽  
Cesarean Delivery ◽  
Maternal Age ◽  
Reference Group ◽  
Multivariate Logistic Regression Analysis ◽  
Advanced Maternal Age ◽  
Adverse Outcomes ◽  
Cross Sectional ◽  
Singleton Pregnancies

Abstract Background To determine the effects of maternal age at first cesarean on maternal complications and adverse outcomes of pregnancy with the second cesarean. Methods This was a multicenter, historical, cross-sectional cohort study involving singleton pregnancies ≥28 gestational weeks, with a history of 1 cesarean delivery, and who underwent a second cesarean between January and December 2017 at 11 public tertiary hospitals in 7 provinces of China. We analyzed the effects of maternal age at first cesarean on adverse outcomes of pregnancy in the second cesarean using multivariate logistic regression analysis. Results The study consisted of 10,206 singleton pregnancies. Women were at first cesarean between 18 and 24, 25–29, 30–34, and ≥ 35 years of age; and numbered 2711, 5524, 1751, and 220 cases, respectively. Maternal age between 18 and 24 years at first cesarean increased the risk of placenta accreta spectrum (aOR, 1.499; 95% CI, 1.12–2.01), placenta previa (aOR, 1.349; 95% CI, 1.07–1.70), intrahepatic cholestasis of pregnancy (aOR, 1.947; 95% CI, 1.24–3.07), postpartum hemorrhage (aOR, 1.505; 95% CI, 1.05–2.16), and blood transfusion (aOR, 1.517; 95% CI, 1.21–1.91) in the second cesarean compared with the reference group (aged 25–29 years). In addition, maternal age ≥ 35 years at first cesarean was a risk factor for premature rupture of membranes (aOR, 1.556; 95% CI, 1.08–2.24), placental abruption (aOR, 6.464, 95% CI, 1.33–31.51), uterine rupture (aOR, 7.952; 95% CI, 1.43–44.10), puerperal infection (aOR, 6.864; 95% CI, 1.95–24.22), neonatal mild asphyxia (aOR, 4.339; 95% CI, 1.53–12.32), severe asphyxia (aOR, 18.439; 95% CI, 1.54–220.95), and admission to a neonatal intensive care unit (aOR, 2.825; 95% CI, 1.54–5.17) compared with the reference group (aged 25–29 years). Conclusions Maternal age between 18 and 24 years or advanced maternal age at first cesarean was an independent risk factor for adverse maternal outcomes with the second cesarean. Advanced maternal age at the first cesarean specifically increased adverse neonatal outcomes with the second. Therefore, decisions as to whether to perform a first cesarean at a young or advanced maternal age must be critically evaluated.

Sign in / Sign up

Export Citation Format

Share Document