scholarly journals 17β-Estradiol enhances α5 integrin subunit gene expression through ERα–Sp1 interaction and reduces cell motility and invasion of ERα-positive breast cancer cells

2010 ◽  
Vol 124 (1) ◽  
pp. 63-77 ◽  
Author(s):  
Diego Sisci ◽  
Emilia Middea ◽  
Catia Morelli ◽  
Marilena Lanzino ◽  
Saveria Aquila ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Cell Motility ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Integrin Subunit ◽  
Subunit Gene ◽  
17Β Estradiol ◽  
Positive Breast Cancer

17β-estradiol (E2) induces cdc25A gene expression in breast cancer cells by genomic and non-genomic pathways

2006 ◽  
Vol 99 (1) ◽  
pp. 209-220 ◽  
Author(s):  
Wan Ru Lee ◽  
Chien-Cheng Chen ◽  
Shengxi Liu ◽  
Stephen Safe
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
17Β Estradiol

scholarly journals EGF Induces Cell Motility and Multi-Drug Resistance Gene Expression in Breast Cancer Cells

Cell Cycle ◽  
2006 ◽  
Vol 5 (23) ◽  
pp. 2820-2826 ◽  
Author(s):  
Ruben Garcia ◽  
Richard A. Franklin ◽  
James A. McCubrey
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Drug Resistance ◽  
Cell Motility ◽  
Cancer Cells ◽  
Resistance Gene ◽  
Breast Cancer Cells ◽  
Multi Drug Resistance ◽  
Drug Resistance Gene

Poly(ADP-ribose) Polymerase-1 Regulates Estrogen-Dependent Gene Expression in Estrogen Receptor α-Positive Breast Cancer Cells

2021 ◽  
pp. molcanres.0103.2021
Author(s):  
Shrikanth S. Gadad ◽  
Cristel V Camacho ◽  
Venkat Malladi ◽  
Charles R Hutti ◽  
Anusha Nagari ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Estrogen Receptor ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Estrogen Receptor Α ◽  
Positive Breast Cancer

scholarly journals Estrogen-Induced Aurora Kinase-A (AURKA) Gene Expression is Activated by GATA-3 in Estrogen Receptor-Positive Breast Cancer Cells

2010 ◽  
Vol 1 (1) ◽  
pp. 11-20 ◽  
Author(s):  
Shoulei Jiang ◽  
Hiroshi Katayama ◽  
Jin Wang ◽  
Sara Antonia Li ◽  
Yan Hong ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Estrogen Receptor ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Aurora Kinase ◽  
Aurora Kinase A ◽  
Estrogen Receptor Positive ◽  
Kinase A ◽  
Positive Breast Cancer

Knockdown of CD151 Gene Expression Reduces Survival of Estrogen Receptor Positive Breast Cancer Cells

2017 ◽  
Vol 06 (03) ◽  
Author(s):  
Gayatri Devi V ◽  
Anil Kuman Badana ◽  
Madhuri Ch ◽  
Murali Mohan P ◽  
Shailandra Naik ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Estrogen Receptor ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Estrogen Receptor Positive ◽  
Positive Breast Cancer

scholarly journals 17β-Estradiol Activates HSF1 via MAPK Signaling in ERα-Positive Breast Cancer Cells

Cancers ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 1533 ◽  
Author(s):  
Natalia Vydra ◽  
Patryk Janus ◽  
Agnieszka Toma-Jonik ◽  
Tomasz Stokowy ◽  
Katarzyna Mrowiec ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Mapk Signaling ◽  
Heat Shock Factor 1 ◽  
Dependent Manner ◽  
Breast Cancer Patients ◽  
17Β Estradiol ◽  
High Level ◽  
Positive Breast Cancer

Heat Shock Factor 1 (HSF1) is a key regulator of gene expression during acute environmental stress that enables the cell survival, which is also involved in different cancer-related processes. A high level of HSF1 in estrogen receptor (ER)-positive breast cancer patients correlated with a worse prognosis. Here we demonstrated that 17β-estradiol (E2), as well as xenoestrogen bisphenol A and ERα agonist propyl pyrazole triol, led to HSF1 phosphorylation on S326 in ERα positive but not in ERα-negative mammary breast cancer cells. Furthermore, we showed that MAPK signaling (via MEK1/2) but not mTOR signaling was involved in E2/ERα-dependent activation of HSF1. E2­activated HSF1 was transcriptionally potent and several genes essential for breast cancer cells growth and/or ERα action, including HSPB8, LHX4, PRKCE, WWC1, and GREB1, were activated by E2 in a HSF1-dependent manner. Our findings suggest a hypothetical positive feedback loop between E2/ERα and HSF1 signaling, which may support the growth of estrogen-dependent tumors.

scholarly journals The role of 17β‑estradiol‑induced upregulation of Piwi‑like�4 in modulating gene expression and motility in breast cancer cells

2018 ◽  
Author(s):  
Zealyn Shi Lin Heng ◽  
Jing Yi Lee ◽  
Charannya Sozheesvari Subhramanyam ◽  
Cheng Wang ◽  
Lal Zo Thanga ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
17Β Estradiol

Abstract 362: EGFR signaling activates S100 gene expression in HER2-positive breast cancer cells

2018 ◽  
Author(s):  
Miguel Nava ◽  
Nathan R. Zemke ◽  
Arnie Berk ◽  
Robin Farias-Eisner ◽  
Jay Vadgama ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Egfr Signaling ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
S100 Gene ◽  
Positive Breast Cancer
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