scholarly journals The role of polycomb group protein Bmi-1 and Notch4 in breast cancer stem cell inhibition by benzyl isothiocyanate

2015 ◽  
Vol 149 (3) ◽  
pp. 681-692 ◽  
Author(s):  
Su-Hyeong Kim ◽  
Shivendra V. Singh
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Polycomb Group ◽  
Breast Cancer Stem Cell ◽  
Polycomb Group Protein ◽  
Benzyl Isothiocyanate ◽  
Group Protein ◽  
Cell Inhibition

Abstract 3327: Role of microRNA221 in breast cancer stem cell expansion and induction of EMT

2012 ◽  
Author(s):  
Jia Ke ◽  
Fayaz A. Malik ◽  
Sean McDermott ◽  
Rachel Martin ◽  
Li Shang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Expansion ◽  
Breast Cancer Stem Cell ◽  
Stem Cell Expansion

scholarly journals Forkhead Box Q1 Is a Novel Target of Breast Cancer Stem Cell Inhibition by Diallyl Trisulfide

2016 ◽  
Vol 291 (26) ◽  
pp. 13495-13508 ◽  
Author(s):  
Su-Hyeong Kim ◽  
Catherine H. Kaschula ◽  
Nolan Priedigkeit ◽  
Adrian V. Lee ◽  
Shivendra V. Singh
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Breast Cancer Stem Cell ◽  
Diallyl Trisulfide ◽  
Forkhead Box ◽  
Novel Target ◽  
Cell Inhibition

scholarly journals Breast Cancer Stem Cell-Like Cells Are More Sensitive to Ionizing Radiation than Non-Stem Cells: Role of ATM

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e50423 ◽  
Author(s):  
Seog-Young Kim ◽  
Juong G. Rhee ◽  
Xinxin Song ◽  
Edward V. Prochownik ◽  
Douglas R. Spitz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Stem Cell ◽  
Ionizing Radiation ◽  
Cancer Stem Cell ◽  
Breast Cancer Stem Cell

Abstract 1123: The role of proto-oncogene PELP1 in breast cancer stem cell maintenance and therapy resistance

2016 ◽  
Author(s):  
Suryavathi Viswanadhapalli ◽  
Monica Mann ◽  
Gangadhara Reddy Sareddy ◽  
Xaionan Lix ◽  
Hariprasad Vankayalapati ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Therapy Resistance ◽  
Breast Cancer Stem Cell ◽  
Stem Cell Maintenance ◽  
Cell Maintenance

scholarly journals The Role of Breast Cancer Stem Cell-Related Biomarkers as Prognostic Factors

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 721
Author(s):  
Clarence Ching Huat Ko ◽  
Wai Kit Chia ◽  
Gayathri Thevi Selvarajah ◽  
Yoke Kqueen Cheah ◽  
Yin Ping Wong ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
High Specificity ◽  
Breast Cancer Diagnosis ◽  
Breast Cancer Stem Cell ◽  
Prognostic Indicators ◽  
Specificity And Sensitivity

Breast cancer is one of the leading causes of cancer-related deaths in women worldwide, and its incidence is on the rise. A small fraction of cancer stem cells was identified within the tumour bulk, which are regarded as cancer-initiating cells, possess self-renewal and propagation potential, and a key driver for tumour heterogeneity and disease progression. Cancer heterogeneity reduces the overall efficacy of chemotherapy and contributes to treatment failure and relapse. The cell-surface and subcellular biomarkers related to breast cancer stem cell (BCSC) phenotypes are increasingly being recognised. These biomarkers are useful for the isolation of BCSCs and can serve as potential therapeutic targets and prognostic tools to monitor treatment responses. Recently, the role of noncoding microRNAs (miRNAs) has extensively been explored as novel biomarker molecules for breast cancer diagnosis and prognosis with high specificity and sensitivity. An in-depth understanding of the biological roles of miRNA in breast carcinogenesis provides insights into the pathways of cancer development and its utility for disease prognostication. This review gives an overview of stem cells, highlights the biomarkers expressed in BCSCs and describes their potential role as prognostic indicators.

Abstract 54: Role of aldehyde dehydrogenase 1 in breast cancer stem cell survival

2010 ◽  
Author(s):  
Min Zhang ◽  
Dale Hogan ◽  
Aramati Bindu Reddy ◽  
Kota Ramana ◽  
Satish Srivastava ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Cell Survival ◽  
Aldehyde Dehydrogenase ◽  
Breast Cancer Stem Cell ◽  
Aldehyde Dehydrogenase 1 ◽  
Stem Cell Survival
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