Surveillance for cancer recurrence in long-term young breast cancer survivors randomly selected from a statewide cancer registry

AbstractDiet may play an important role in breast cancer recurrence or survival, and therefore assessment of long-term diet among breast cancer survivors is important in breast cancer survivorship research. Given that the diet of breast cancer survivors may differ from that of the general population, the use of a FFQ specific to this group may be needed. The objective of this study was to develop a FFQ for breast cancer survivors, the most commonly used tool to measure long-term dietary patterns in nutritional epidemiological studies. We collected information on the foods and amounts of foods consumed using 3-d dietary records from a total of 192 women who had been diagnosed with stage I–III breast cancers and had undergone breast cancer surgery at least 6 months before the baseline study. A total of 1254 foods and dishes consumed were re-grouped by the similarity of the main ingredients and/or serving units, and several dishes commonly consumed among the Korean population were added. After we performed contribution analyses and variability analyses to detect between-person variation for selected nutrients, we listed a total of 123 foods and dishes for the FFQ specific to breast cancer survivors. Our breast cancer survivor-specific FFQ can be used to estimate long-term dietary intake and to examine its association with breast cancer prognosis in epidemiological studies of breast cancer in Korea.

Download Full-text

Follow-up of long-term young breast cancer survivors.

Journal of Clinical Oncology ◽

10.1200/jco.2012.30.34_suppl.8 ◽

2012 ◽

Vol 30 (34_suppl) ◽

pp. 8-8

Author(s):

Corinne Daly ◽

Elisabeth M. Del Giudice ◽

Rinku Sutradhar ◽

Lawrence Frank Paszat ◽

Drew Wilton ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Survivors ◽

Cancer Registry ◽

Breast Cancer Survivors ◽

Negative Binomial ◽

Population Based ◽

Cancer Center ◽

Physician Visits ◽

Young Breast Cancer

8 Background: Evidence suggests breast cancer patients can be offered follow-up by family physician without concern of important recurrence–related serious clinical events occurring more frequently or quality of life being negatively affected. This study describes population-based patterns of follow-up care in 5-year recurrence-free young breast cancer survivors to determine factors influencing continued oncology follow-up in Ontario, Canada. Methods: We conducted a retrospective population-based cohort study using cancer registry and administrative data. Women diagnosed with an incident breast cancer aged 20-44 between 1992 and 1999, survived for at least 5 years and recurrence-free for 5 years past diagnosis were identified in the Ontario Cancer Registry. Each survivor was matched to 5 control women with the same calendar year of birth and place of residence in Ontario. We determined outpatient physician visits with primary care, medical, radiation and surgical oncology physicians to investigate trends associated with increasing survivorship and compared visit rates to controls. We used negative binomial regression to investigate factors predicting high utilization of oncology services among survivors after 5-year recurrence survival. Results: We identified 4,581 survivors and 22,898 controls. By year 10, 51% breast cancer survivors were still being followed by an oncologist. In the survivors, fewer physician visits were observed among recurrence-free breast cancer survivors as time increased from diagnosis (Visit Rate Ratio [VRR] =0.95, 95% CI: 0.94, 0.96). Breast cancer survivors diagnosed from 1992-1995 had a higher rate of physician visits than those diagnosed from 1996-1999 (VRR = 1.16, 95% CI: 1.07, 1.25). More oncologist visits were associated with patients visiting a female oncologist (VRR = 1.20, 95% CI: 1.09, 1.33) and fewer visits were associated with patients visiting an oncologist who practiced outside of a regional cancer center (VRR = 0.67, 95% CI: 0.58, 0.77). Conclusions: Oncology visits of young breast cancer survivors after 5-year survival were associated with oncologist factors indicating that prolonged oncology follow-up in breast cancer survivors may be driven by practice patterns rather than patients’ needs.

Download Full-text

The impact of fear of cancer recurrence on healthcare utilization among long‐term breast cancer survivors recruited through ECOG‐ACRIN trials

Psycho-Oncology ◽

10.1002/pon.5568 ◽

2020 ◽

Author(s):

Eric Vachon ◽

Ellen Krueger ◽

Victoria L. Champion ◽

David A. Haggstrom ◽

David Cella ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Survivors ◽

Healthcare Utilization ◽

Breast Cancer Survivors ◽

Cancer Recurrence ◽

Fear Of Cancer Recurrence ◽

Fear Of Cancer ◽

The Impact

Download Full-text

Long-term fear of recurrence in young breast cancer survivors and partners

Psycho-Oncology ◽

10.1002/pon.4008 ◽

2015 ◽

Vol 26 (1) ◽

pp. 22-28 ◽

Cited By ~ 32

Author(s):

Andrea A. Cohee ◽

Rebecca N. Adams ◽

Shelley A. Johns ◽

Diane Von Ah ◽

Kathleen Zoppi ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Survivors ◽

Breast Cancer Survivors ◽

Fear Of Recurrence ◽

Young Breast Cancer

Download Full-text

Predictors and interdependence of family support in a random sample of long-term young breast cancer survivors and their biological relatives

Cancer Medicine ◽

10.1002/cam4.1766 ◽

2018 ◽

Vol 7 (10) ◽

pp. 4980-4992 ◽

Cited By ~ 3

Author(s):

Maria C. Katapodi ◽

Katrina R. Ellis ◽

Franziska Schmidt ◽

Christos Nikolaidis ◽

Laurel L. Northouse

Keyword(s):

Breast Cancer ◽

Cancer Survivors ◽

Family Support ◽

Random Sample ◽

Breast Cancer Survivors ◽

Young Breast Cancer

Download Full-text

Adherence to adjuvant endocrine therapy among breast cancer survivors: a systematic review and meta-synthesis of the qualitative literature using grounded theory

Supportive Care in Cancer ◽

10.1007/s00520-020-05585-9 ◽

2020 ◽

Vol 28 (11) ◽

pp. 5075-5084 ◽

Cited By ~ 1

Author(s):

Othman AlOmeir ◽

Nilesh Patel ◽

Parastou Donyai

Keyword(s):

Breast Cancer ◽

Grounded Theory ◽

Cancer Survivors ◽

Endocrine Therapy ◽

Breast Cancer Survivors ◽

Cancer Recurrence ◽

Qualitative Studies ◽

Adjuvant Endocrine Therapy ◽

Medication Side

Abstract Purpose Numerous studies have examined non-adherence to adjuvant endocrine therapy in women recovering from breast cancer, but none provides a comprehensive theory to explain the challenges of long-term medication taking and resilience needed to continue. The aim of this study was to source, appraise, and synthesize data from existing qualitative studies to develop an in-depth explanatory model of non-adherence and discontinuation of hormonal medication among breast cancer survivors. Methods A comprehensive search of databases and the literature identified 24 eligible qualitative studies published 2010–2019. Quotations (n = 801) listed within these papers and the original author interpretations were synthesized using NVivo, and grounded theory methodology. Results At the beginning, knowledge about adjuvant endocrine therapy, trust in doctors, and worries and expectations, mean agreeing to medication is the only viable option, akin to a Hobson’s choice. Thereafter, women’s ability to deal with medication side-effects, knowledge and support received affect their decision to continue, akin to a horned dilemma where giving up the medication risks cancer recurrence and continuing means reduced contentment. Women stopping medication altogether question treatment necessity, search for normalcy and prioritize quality of life. Conclusion Shared experiences and understandings were uncovered by examining commonalities in existing publications. The core category explained the difficulties women face with the initial decision to accept long-term endocrine therapy and then the everyday challenges of continuing or deciding to stop treatment early. An educational tool to inform survivors and health professionals about these challenges could potentially improve women’s experience on treatment and in turn their adherence.

Download Full-text

Individual courses and determinants of fear of cancer recurrence in long-term breast cancer survivors with and without recurrence

Supportive Care in Cancer ◽

10.1007/s00520-021-06329-z ◽

2021 ◽

Author(s):

Paula Heidkamp ◽

Clara Breidenbach ◽

Kati Hiltrop ◽

Christoph Kowalski ◽

Anna Enders ◽

...

Keyword(s):

Breast Cancer ◽

Logistic Regression ◽

Cancer Survivors ◽

Breast Cancer Survivors ◽

Cancer Recurrence ◽

Fear Of Cancer Recurrence ◽

Chi Square ◽

Need For Support ◽

Fear Of Cancer

Abstract Objective This study investigated the prevalence, individual courses, and determinants of fear of cancer recurrence (FoR) in long-term breast cancer survivors (BCSs) with and without recurrence. Methods A total of 184 breast cancer survivors were surveyed at four measurement time points: during hospitalization (T1), 10 weeks (T2), 40 weeks (T3), and 5–6 years (T4) after hospital discharge. Descriptive statistics, chi-square tests, and logistic regression were performed. Results Respondents were females and 57 years old, on average. At T1, T3, and T4, 54.8%, 31.6%, and 29.7% of BCSs, respectively, were classified as having dysfunctional levels of FoR. Dysfunctional FoR decreased from T1 to T3 (χ2(1) = 17.11, p = 0.000; N = 163) and remained stable afterwards. Eight subgroups of individual courses of FoR over time could be described: (1) constant functional FoR; (2) constant dysfunctional FoR; (3) improving from dysfunctional to functional FoR from T1 to T3; (4) improving from dysfunctional to functional FoR from T3 to T4; (5) worsening from functional to dysfunctional FoR from T1 to T3; (6) worsening from functional to dysfunctional FoR from T3 to T4; (7) dysfunctional FoR at T1 and T4, and functional FoR in between; and (8) functional FoR at T1 and T4, and dysfunctional FoR in between. Logistic regression analysis revealed that being divorced/widowed, showing high levels of fatigue, being treated by chemotherapy, and having low confidence in treatment were associated with dysfunctional FoR 5 to 6 years after diagnosis (Nagelkerkes’ Pseudo-R2 = 0.648). Conclusions The findings reveal that FoR is a significant issue in long-term BCSs and has the potential to become a persistent psychological strain. We emphasize the need for increased awareness of FoR among BCSs and the need for support programs.

Download Full-text