scholarly journals Dietary carbohydrate, glycemic index, glycemic load, and risk of prostate cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort

2011 ◽  
Vol 22 (7) ◽  
pp. 995-1002 ◽  
Author(s):  
James M. Shikany ◽  
Andrew P. Flood ◽  
Cari M. Kitahara ◽  
Ann W. Hsing ◽  
Tamra E. Meyer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Ovarian Cancer ◽  
Cancer Screening ◽  
Glycemic Index ◽  
Glycemic Load ◽  
Dietary Carbohydrate ◽  
Ovarian Cancer Screening ◽  
Cancer Screening Trial ◽  
Screening Trial

scholarly journals Dietary consumption of tea and the risk of prostate cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial

2021 ◽  
pp. 1-16
Author(s):  
Robert Thomas ◽  
Basma Greef ◽  
Alex McConnachie ◽  
Bethany Stanley ◽  
Madeleine Williams
Keyword(s):  
Prostate Cancer ◽  
Ovarian Cancer ◽  
Cancer Screening ◽  
Cox Regression ◽  
Positive Association ◽  
Epidemiological Studies ◽  
Tea Consumption ◽  
Ovarian Cancer Screening ◽  
Cancer Screening Trial ◽  
Screening Trial

Abstract Tea contains polyphenols such as flavonoids, anthocyanidins, flavanols and phenolic acids which in laboratory studies have reported to promote antioxidant enzyme formation, reduces excess inflammation, slow cancer cell proliferation and promote apoptosis. Evidence from epidemiological studies, on the effect of tea consumption on CaP incidence has been conflicting. We analysed data from 25 097 men within the intervention arm of the 155000 participant Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial screening trial. Histologically confirmed cases of prostate cancer were reported in 3,088 men (12.3%) during the median 11.5 year follow up. Tea consumption was assessed with a food frequency questionnaire. Baseline characteristics were compared between groups using Chi-square and Kruskal-Wallis tests. Cox regression models were used to assess associations between tea intake and CaP incidence. There was no statistical difference between the risk of CaP between men who never drank tea to those who drank tea at any quantity. Amongst tea drinkers, those in the highest third of consumption group had a small but significantly lower risk compared to those in the lowest third (11.2% v 13.2% HR 1.16; 95% CI 1.05-1.29, p=0.004). This pattern persisted with adjustments for demographics and lifestyle. In conclusion, among tea drinkers, there was a small positive association between drinking tea and a reduced risk of prostate cancer. It does not support starting to drink tea, if men previously did not, to reduce the risk. Further research is needed to establish whether tea is justified for future prospective nutritional intervention studies investigating CaP prevention.

scholarly journals Metastatic prostate cancer at diagnosis and through progression in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

Cancer ◽  
2019 ◽  
Vol 125 (17) ◽  
pp. 2965-2974
Author(s):  
Paul F. Pinsky ◽  
Amanda Black ◽  
Sarah E. Daugherty ◽  
Robert Hoover ◽  
Howard Parnes ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Ovarian Cancer ◽  
Cancer Screening ◽  
Metastatic Prostate Cancer ◽  
Ovarian Cancer Screening ◽  
Cancer Screening Trial ◽  
Screening Trial

scholarly journals IGF-1 and IGFBP-3: Risk of prostate cancer among men in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial

2007 ◽  
Vol 121 (10) ◽  
pp. 2267-2273 ◽  
Author(s):  
Jocelyn M. Weiss ◽  
Wen-Yi Huang ◽  
Sabina Rinaldi ◽  
Thomas R. Fears ◽  
Nilanjan Chatterjee ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Ovarian Cancer ◽  
Cancer Screening ◽  
Ovarian Cancer Screening ◽  
Cancer Screening Trial ◽  
Screening Trial ◽  
Igfbp 3
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