Left ventricular energy loss and wall shear stress assessed by vector flow mapping in patients with hypertrophic cardiomyopathy

2018 ◽  
Vol 34 (9) ◽  
pp. 1383-1391 ◽  
Author(s):  
Ling Ji ◽  
Wenzhi Hu ◽  
Yonghong Yong ◽  
Hongping Wu ◽  
Lei Zhou ◽  
...  

2021 ◽  
Author(s):  
Li-ping Dong ◽  
Zhen-zhen Wang ◽  
Hai-ru Li ◽  
Wei-dong Yu ◽  
jiawei tian

Abstract Objective To observe the diastolic wall shear stress (WSS) pattern of the left ventricle (LV) by using vector flow mapping (VFM) in normal subjects. Methods A total of 371 healthy volunteers were recruited into this study and divided into four age groups. The LV WSS was measured at each diastolic phase, and the mapping of WSS was analyzed. Results Among groups I, II and III, The absolute value of WSS of Anterolateral,Inferoseptal and Anterospetal segments in phase D1;WSS values of inferolateral,Inferoseptal and Anterospetal segments in phase D4 all showed an increasing trend with age. In terms of gender differences, In most cases,women had greater diastolic WSS values compared to men. For each age group, the log-transformed WSS value appeared the increasing-decreasing-increasing trend from phase D1 to D4, with a peak value at the rapid filling phase.Multivariate backward stepwise linear regression analysis revealed that the certain segments log-transformed WSS was independently related to conventional parameters in evaluating diastolic function(mitral lateral E/e', septal E/e', mitral lateral e', septal e' and LAVI).Conclusions In diastolic period, segmental LV WSS shows a regular variation phenomenon and has specific age- and gender-related patterns in different diastolic phases. The mapping of WSS may help identify the diastolic hemodynamic changes or diastolic function phase by phase.



2020 ◽  
Vol 46 (10) ◽  
pp. 2692-2699
Author(s):  
Kozue Saito ◽  
Soichiro Abe ◽  
Masaya Kumamoto ◽  
Yuto Uchihara ◽  
Akito Tanaka ◽  
...  




2021 ◽  
Vol 12 ◽  
Author(s):  
Yu Wang ◽  
Junwei Wang ◽  
Jing Peng ◽  
Mingming Huo ◽  
Zhiqiang Yang ◽  
...  

Patients with heart failure (HF) or undergoing cardiogenic shock and percutaneous coronary intervention require short-term cardiac support. Short-term cardiac support using a left ventricular assist device (LVAD) alters the pressure and flows of the vasculature by enhancing perfusion and improving the hemodynamic performance for the HF patients. However, due to the position of the inflow and outflow of the LVAD, the local hemodynamics within the aorta is altered with the LVAD support. Specifically, blood velocity, wall shear stress, and pressure difference are altered within the aorta. In this study, computational fluid dynamics (CFD) was used to elucidate the effects of a short-term LVAD for hemodynamic performance in a patient-specific aorta model. The three-dimensional (3D) geometric models of a patient-specific aorta and a short-term LVAD, Impella CP, were created. Velocity, wall shear stress, and pressure difference in the patient-specific aorta model with the Impella CP assistance were calculated and compared with the baseline values of the aorta without Impella CP support. Impella CP support augmented cardiac output, blood velocity, wall shear stress, and pressure difference in the aorta. The proposed CFD study could analyze the quantitative changes in the important hemodynamic parameters while considering the effects of Impella CP, and provide a scientific basis for further predicting and assessing the effects of these hemodynamic signals on the aorta.



Author(s):  
Florian von Knobelsdorff-Brenkenhoff ◽  
Achudhan Karunaharamoorthy ◽  
Ralf Felix Trauzeddel ◽  
Alex J. Barker ◽  
Edyta Blaszczyk ◽  
...  


2006 ◽  
Vol 27 (3) ◽  
pp. 309-315 ◽  
Author(s):  
K.R. Moyle ◽  
G.D. Mallinson ◽  
C.J. Occleshaw ◽  
B.R. Cowan ◽  
T.L. Gentles


2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Neichuan Zhang ◽  
Haiyun Yuan ◽  
Xiangyu Chen ◽  
Jiawei Liu ◽  
Qifei Jian ◽  
...  

Studying the haemodynamics of the central shunt (CS) and modified Blalock–Taussig shunt (MBTS) benefits the improvement of postoperative recovery for patients with an aorta-pulmonary shunt. Shunt configurations, including CS and MBTS, are virtually reconstructed for infants A and B based on preoperative CT data, and three-dimensional models of A, 11 months after CS, and B, 8 months after MBTS, are reconstructed based on postoperative CT data. A series of parameters including energy loss, wall shear stress, and shunt ratio are computed from simulation to analyse the haemodynamics of CS and MBTS. Our results showed that the shunt ratio of the CS is approximately 30% higher than the MBTS and velocity distribution in the left pulmonary artery (LPA) and right pulmonary artery (RPA) was closer to a natural development in the CS than the MBTS. However, energy loss of the MBTS is lower, and the MBTS can provide more symmetric pulmonary artery (PA) flow than the CS. With the growth of infants A and B, the shunt ratio of infants was decreased, but maximum wall shear stress and the distribution region of high wall shear stress (WSS) were increased, which raises the probability of thrombosis. For infant A, the preoperative abnormal PA structure directly resulted in asymmetric growth of PA after operation, and the LPA/RPA ratio decreased from 0.49 to 0.25. Insufficient reserved length of the MBTS led to traction phenomena with the growth of infant B; on the one hand, it increased the eddy current, and on the other hand, it increased the flow resistance of anastomosis, promoting asymmetric PA flow.



2016 ◽  
Vol 42 (8) ◽  
pp. 1730-1740 ◽  
Author(s):  
Yi Wang ◽  
Rongchuan Ma ◽  
Geqi Ding ◽  
Dailun Hou ◽  
Zhaohuan Li ◽  
...  


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