The predictive value of left ventricular and left atrial mechanics for atrial fibrillation and heart failure in hypertrophic cardiomyopathy: a prospective cohort study

2021 ◽  
Author(s):  
Thomas Zegkos ◽  
Dimitris Ntelios ◽  
Despoina Parcharidou ◽  
Sotiris Katranas ◽  
Theofilos Panagiotidis ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Cohort Study ◽  
Hypertrophic Cardiomyopathy ◽  
Prospective Cohort Study ◽  
Predictive Value ◽  
Prospective Cohort ◽  
Left Atrial ◽  
Left Ventricular ◽  
Left Atrial Mechanics

The association of left atrial size and occurrence of atrial fibrillation: A prospective cohort study from the Canadian Registry of Atrial Fibrillation

2004 ◽  
Vol 148 (4) ◽  
pp. 649-654 ◽  
Author(s):  
Ratika Parkash ◽  
Martin S. Green ◽  
Charles R. Kerr ◽  
Stuart J. Connolly ◽  
George J. Klein ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Left Atrial ◽  
Left Atrial Size ◽  
Atrial Size

P1766Clinical impact of atrial fibrillation and heart failure in a cohort of patients with hypertrophic cardiomyopathy

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
I Esteve Ruiz ◽  
H Llamas Gomez ◽  
I M Esteve Ruiz ◽  
M J Romero Reyes ◽  
R Pavon Jimenez ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Atrial Fibrillation ◽  
Hypertrophic Cardiomyopathy ◽  
Left Atrial ◽  
Left Ventricular ◽  
Left Atrial Diameter ◽  
Myocardial Thickness ◽  
Worse Prognosis ◽  
Echocardiographic Findings

Abstract Background Atrial fibrillation (AF) and heart failure (HF) are common complications in Hypertrophic Cardiomyopathy (HCM) patients, leading to a worsening of their quality of life, need of hospitalization and prognosis. Purpose To analyze clinical variables associated with the presence of AF and HF in HCM patients. Methods HCM patients followed-up in cardiological visits from 2005 to 2017 were included and a descriptive analysis of those with AF and HF was performed. Results Out of 168 patients, 28% had reported AF. They were older than those without arrhythmia (68±15 years (yrs) vs 56±20 yrs, p<0.001) and had more comorbidities such as diabetes (27.7% vs 12.4%, p=0.02) and chronic renal disease (21.3% vs 6.6%, p=0.006). Echocardiographic findings are summarized in Table 1. In our cohort, 27.4% of the patients had HF with a functional class according to the New York Heart Association criteria ≥2. They were older than those without HF (69.3±11.6 yrs vs 55.9±20.6 yrs, p<0.001) and had higher rate of cardiovascular (CV) risk factors such as hypertension (65.2% vs 44.3%, p=0.015). The presence of HF was directly associated with the presence of AF: 52.2% of the patients with HF and 18.9% of the patients without HF developed this arrhythmia (p<0.001). HF patients associated larger left atrial diameter (48±8.1 vs 41.6±7.2mm, p<0.001), myocardial thickness (21.7±3.9 vs 19.2±5.8mm, p=0.002) and higher left ventricular outflow obstruction (LVOO) (55±32 vs 34.3±31.3mmHg, p=0.021), without any differences in the left ventricular ejection fraction. HF patients had a worse prognosis (Picture 1). Multivariate analysis showed that the presence of AF (OR 2.6, CI 95% 1.1–6.3) and LVOO (OR 4.8, CI 95% 1.5–14.8) were independent risk factors of developing HF. Table 1. Echocardiographic findings AF (n=47) Non AF (n=121) p LVOO 27.7 19 0.22 Aortic regurgitation 12.8 3.3 0.02 Mitral regurgitation 27.7 12.4 0.02 Left atrial diameter (mm) 48.8±7.2 40.7±7 <0.001 Myocardial thickness (mm) 20±5.4 19±5.2 0.02 Qualitative variables are expressed as percentages (%) and quantitative variables as mean and standard deviation (M ± SD). Picture 1. Main outcomes of HF patients Conclusions AF and HF were directly associated in our cohort, especially in elderly patients with higher comorbidities, leading to a worse prognosis with a higher hospitalization rate and CV death. This emphasizes the importance of a thorough search of both complications in order to initiate early treatment and improve the prognosis of HCM patients.

scholarly journals Association of the CHADS2 and CHA2DS2-VASc scores with left atrial enlargement: a prospective cohort study of unselected atrial fibrillation patients

2014 ◽  
Vol 40 (2) ◽  
pp. 240-247 ◽  
Author(s):  
Anna Hrynkiewicz-Szymanska ◽  
Miroslaw Dluzniewski ◽  
Anna E. Platek ◽  
Filip M. Szymanski ◽  
Joanna Syska-Suminska ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Left Atrial ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

scholarly journals Cadmium exposure and incidence of heart failure and atrial fibrillation: a population-based prospective cohort study

BMJ Open ◽  
2015 ◽  
Vol 5 (6) ◽  
pp. e007366-e007366 ◽  
Author(s):  
Y. Borne ◽  
L. Barregard ◽  
M. Persson ◽  
B. Hedblad ◽  
B. Fagerberg ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Population Based ◽  
Cadmium Exposure

scholarly journals Contrast echocardiography for assessing left ventricular vortex strength in heart failure: a prospective cohort study

2013 ◽  
Vol 14 (11) ◽  
pp. 1049-1060 ◽  
Author(s):  
Haruhiko Abe ◽  
Giuseppe Caracciolo ◽  
Arash Kheradvar ◽  
Gianni Pedrizzetti ◽  
Bijoy K. Khandheria ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Contrast Echocardiography ◽  
Left Ventricular ◽  
Vortex Strength
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