Haematopoiesis in the head kidney of common carp (Cyprinus carpio L.): a morphological study

2010 ◽  
Vol 37 (3) ◽  
pp. 355-362 ◽  
Author(s):  
Elżbieta Kondera
Keyword(s):  
Common Carp ◽  
Cyprinus Carpio ◽  
Morphological Study ◽  
Head Kidney ◽  
Common Carp Cyprinus Carpio ◽  
Carp Cyprinus Carpio

scholarly journals Identification of an IRF10 gene in common carp (Cyprinus carpio L.) and analysis of its function in the antiviral and antibacterial immune response

2020 ◽  
Author(s):  
Yaoyao Zhu ◽  
Shijuan Shan ◽  
Huaping Zhao ◽  
Rongrong Liu ◽  
Hui Wang ◽  
...  
Keyword(s):  
Common Carp ◽  
Cyprinus Carpio ◽  
Head Kidney ◽  
Ctenopharyngodon Idella ◽  
Poly I:C ◽  
Type I ◽  
Regulatory Factors ◽  
Common Carp Cyprinus Carpio ◽  
Transcriptional Regulatory ◽  
Carp Cyprinus Carpio

Abstract Background: Interferon (IFN) regulatory factors (IRFs), as transcriptional regulatory factors, play important roles in regulating the expression of type I IFN and IFN stimulated genes (ISGs) in innate immune responses. In addition, they participate in cell growth and development and regulate oncogenesis. Results: In the present study, the cDNA sequence of IRF10 in common carp (Cyprinus carpio L.) was characterized (abbreviation, CcIRF10). The predicted protein sequence of CcIRF10 shared 52.7-89.2% identity with other teleost IRF10s and contained a DNA-binding domain (DBD), a nuclear localization signal (NLS) and an IRF-associated domain (IAD). Phylogenetic analysis showed that CcIRF10 had the closest relationship with IRF10 of Ctenopharyngodon idella. CcIRF10 transcripts were detectable in all examined tissues, with the highest expression in the gonad and the lowest expression in the head kidney. CcIRF10 expression was upregulated in the spleen, head kidney, foregut and hindgut upon polyinosinic:polycytidylic acid (poly I:C) and Aeromonas hydrophila stimulation and induced by poly I:C, lipopolysaccharide (LPS) and peptidoglycan (PGN) in peripheral blood leucocytes (PBLs) and head kidney leukocytes (HKLs) of C. carpio. In addition, overexpression of CcIRF10 was able to decrease the expression of the IFN and IFN stimulated genes PKR and ISG15. Conclusions: These results indicate that CcIRF10 participates in antiviral and antibacterial immunity and negatively regulates the IFN response, which provides new insights into the IFN system of C. carpio.

Orally administered LPS enhances head kidney macrophage activation with down-regulation of IL-6 in common carp (Cyprinus carpio)

2013 ◽  
Vol 34 (6) ◽  
pp. 1569-1575 ◽  
Author(s):  
Takeshi Kadowaki ◽  
Yasumasa Yasui ◽  
Osamu Nishimiya ◽  
Yukinori Takahashi ◽  
Chie Kohchi ◽  
...  
Keyword(s):  
Common Carp ◽  
Cyprinus Carpio ◽  
Macrophage Activation ◽  
Head Kidney ◽  
Down Regulation ◽  
Common Carp Cyprinus Carpio ◽  
Carp Cyprinus Carpio

scholarly journals Head Kidney-Derived Macrophages of Common Carp (Cyprinus carpio L.) Show Plasticity and Functional Polarization upon Differential Stimulation

2006 ◽  
Vol 177 (1) ◽  
pp. 61-69 ◽  
Author(s):  
Maaike Joerink ◽  
Carla M. S. Ribeiro ◽  
René J. M. Stet ◽  
Trudi Hermsen ◽  
Huub F. J. Savelkoul ◽  
...  
Keyword(s):  
Common Carp ◽  
Cyprinus Carpio ◽  
Head Kidney ◽  
Common Carp Cyprinus Carpio ◽  
Carp Cyprinus Carpio ◽  
Functional Polarization
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