Expression Pattern and Immunoregulatory Roles of Galectin-1 and Galectin-3 in Atopic Dermatitis and Psoriasis

Inflammation ◽  
2022 ◽  
Author(s):  
Mab P. Corrêa ◽  
Rebeca D. Correia-Silva ◽  
Gisela R. Silva Sasso ◽  
Solange C. G. P. D’Ávila ◽  
Karin V. Greco ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Expression Pattern ◽  
Galectin 3

Alteration of the cytoplasmic/nuclear expression pattern of galectin-3 correlates with prostate carcinoma progression

2000 ◽  
Vol 89 (4) ◽  
pp. 361-367 ◽  
Author(s):  
Fr�d�ric A. van den Br�le ◽  
David Waltregny ◽  
Fu-Tong Liu ◽  
Vincent Castronovo
Keyword(s):  
Expression Pattern ◽  
Prostate Carcinoma ◽  
Nuclear Expression ◽  
Galectin 3

scholarly journals THE EXPRESSION PATTERN OF GALECTIN-3 IN THE RAT HEPATOCELLULAR CARCINOMA

2011 ◽  
Vol 34 (2) ◽  
pp. 181-187
Author(s):  
Omar Mohafez ◽  
Mohamed Abd EL-Aziz ◽  
Ahmed Abd El-Ghany
Keyword(s):  
Hepatocellular Carcinoma ◽  
Expression Pattern ◽  
Galectin 3

scholarly journals Neuroinflammatory Gene Expression Pattern Is Similar between Allergic Rhinitis and Atopic Dermatitis but Distinct from Atopic Asthma

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Paulina Sobkowiak ◽  
Wojciech Langwiński ◽  
Joanna Nowakowska ◽  
Irena Wojsyk-Banaszak ◽  
Dawid Szczepankiewicz ◽  
...  
Keyword(s):  
Gene Expression ◽  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Expression Pattern ◽  
Human Study ◽  
Allergic Inflammation ◽  
Allergic Diseases ◽  
Atopic Asthma ◽  
Control Group ◽  
Altered Expression

Background and Aim. Neurogenic inflammation underlies the pathogenesis of allergic diseases. Interactions between neurons with the immune cells and structural cells (airway epithelium, nasal mucosa, skin keratinocytes) undergo altered regulation during chronic inflammation. Therefore, we hypothesized that the expression of neuroinflammatory genes may be altered allergic diseases, including atopic dermatitis and allergic rhinitis, and that, compared to atopic asthma, the expression pattern may be disease-specific in pediatric patients. Methods. In the study, we included 86 children diagnosed with atopic asthma (n=25), allergic rhinitis (n=20), and atopic dermatitis (n=20) and healthy control subjects (n=21) of Caucasian origin from the Polish population. The blood leukocyte expression of 31 genes involved in neuroinflammatory response (neurotrophins, their receptors, neuropeptides, and histamine signaling pathway) was analysed using TaqMan low-density arrays. The relative expression of selected proteins from plasma was done using TaqMan Protein Assays. Statistical analysis was done using Statistica. Results. Blood expression of 31 genes related to neuroimmune interactions showed significant increase in both allergic diseases, allergic rhinitis and atopic dermatitis, in comparison to the control group. We found 12 genes significantly increased in allergic rhinitis and 9 genes in which the expression was elevated in atopic dermatitis. Moreover, 9 genes with changed expression in atopic dermatitis overlapped with those in allergic rhinitis. Atopic asthma showed 5 genes with altered expression. The peripheral expression of neuroinflammatory genes in the human study was verified in target tissues (nasal epithelium and skin) in a rat model of allergic inflammation. Conclusions. A common pattern of neuroinflammatory gene expression between allergic rhinitis and atopic dermatitis may reflect similar changes in sensory nerve function during chronic allergic inflammation.

Expression pattern of galectin-3 in neural tumor cell lines

2000 ◽  
Vol 60 (1) ◽  
pp. 45-57 ◽  
Author(s):  
Stephan Kuklinski ◽  
Penka Pesheva ◽  
Cornelia Heimann ◽  
Stephanie Urschel ◽  
Sergio Gloor ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Expression Pattern ◽  
Cell Lines ◽  
Tumor Cell Lines ◽  
Galectin 3 ◽  
Neural Tumor

scholarly journals Galectin-3 Is Critical for the Development of the Allergic Inflammatory Response in a Mouse Model of Atopic Dermatitis

2009 ◽  
Vol 174 (3) ◽  
pp. 922-931 ◽  
Author(s):  
Jun Saegusa ◽  
Daniel K. Hsu ◽  
Huan-Yuan Chen ◽  
Lan Yu ◽  
Agnes Fermin ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Inflammatory Response ◽  
Mouse Model ◽  
Galectin 3

Expression pattern of galectin-1 and galectin-3 in rat testes and epididymis during postnatal development

2018 ◽  
Vol 120 (8) ◽  
pp. 814-827 ◽  
Author(s):  
Mehmet Özbek ◽  
Mustafa Hitit ◽  
Nuh Yıldırım ◽  
Özge Özgenç ◽  
Emel Ergün ◽  
...  
Keyword(s):  
Postnatal Development ◽  
Expression Pattern ◽  
Galectin 3

Changes in the expression pattern of apoptotic molecules (galectin-3, Bcl-2, Bax, survivin) during progression of thyroid malignancy and their clinical significance

2014 ◽  
Vol 127 (9-10) ◽  
pp. 337-344 ◽  
Author(s):  
Sonja A. Selemetjev ◽  
Svetlana B. Savin ◽  
Ivan R. Paunovic ◽  
Svetislav B. Tatic ◽  
Dubravka Cvejic
Keyword(s):  
Expression Pattern ◽  
Clinical Significance ◽  
Thyroid Malignancy ◽  
Galectin 3

IL-15 Expression Pattern in Atopic Dermatitis

2020 ◽  
Vol 181 (6) ◽  
pp. 417-421 ◽  
Author(s):  
Hélène Karlen ◽  
Shida Yousefi ◽  
Hans-Uwe Simon ◽  
Dagmar Simon
Keyword(s):  
Atopic Dermatitis ◽  
Expression Pattern
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