The function of Nucleoporin 37 on mouse oocyte maturation and preimplantation embryo development

Author(s):  
Qianying Guo ◽  
Qiang Liu ◽  
Nan Wang ◽  
Jing Wang ◽  
Andi Sun ◽  
...  
2009 ◽  
Vol 19 (2) ◽  
pp. 181-190 ◽  
Author(s):  
Yinghui Ye ◽  
Kazuhiro Kawamura ◽  
Mitsue Sasaki ◽  
Nanami Kawamura ◽  
Peter Groenen ◽  
...  

iScience ◽  
2020 ◽  
Vol 23 (9) ◽  
pp. 101523
Author(s):  
Alaa A. Eisa ◽  
Scott Bang ◽  
Katherine J. Crawford ◽  
Emily M. Murphy ◽  
William W. Feng ◽  
...  

Reproduction ◽  
2011 ◽  
Vol 141 (4) ◽  
pp. 417-424 ◽  
Author(s):  
Pan-Pan Cheng ◽  
Jun-Jie Xia ◽  
Hai-Long Wang ◽  
Ji-Bing Chen ◽  
Fei-Yu Wang ◽  
...  

Maternal diabetes adversely affects preimplantation embryo development and oocyte maturation. Thus, it is important to identify ways to eliminate the effects of maternal diabetes on preimplantation embryos and oocytes. The objectives of this study were to investigate whether islet transplantation could reverse the effects of diabetes on oocytes. Our results revealed that maternal diabetes induced decreased ovulation; increased the frequency of meiotic spindle defects, chromosome misalignment, and aneuploidy; increased the relative expression levels of Mad2 and Bub1; and enhanced the sensitivity of oocytes to parthenogenetic activation. Islet transplantation prevented these detrimental effects. Therefore, we concluded that islet transplantation could reverse the effects of diabetes on oocytes, and that this technique may be useful to treat the fundamental reproductive problems of women with diabetes mellitus.


2016 ◽  
Vol 65 ◽  
pp. 159-169 ◽  
Author(s):  
Eric J. Schoevers ◽  
Regiane R. Santos ◽  
Johanna Fink-Gremmels ◽  
Bernard A.J. Roelen

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