Acceptability of, and Information Needs Regarding, Next-Generation Sequencing in People Tested for Hereditary Cancer: A Qualitative Study

2015 ◽  
Vol 25 (2) ◽  
pp. 218-227 ◽  
Author(s):  
Bettina Meiser ◽  
Ben Storey ◽  
Veronica Quinn ◽  
Belinda Rahman ◽  
Lesley Andrews
Keyword(s):  
Next Generation Sequencing ◽  
Qualitative Study ◽  
Hereditary Cancer ◽  
Information Needs ◽  
Next Generation ◽  
Generation Sequencing

scholarly journals Clinical Integration of Next Generation Sequencing: Coverage and Reimbursement Challenges

2014 ◽  
Vol 42 (S1) ◽  
pp. 22-41 ◽  
Author(s):  
Patricia A. Deverka ◽  
Jennifer C. Dreyfus
Keyword(s):  
Next Generation Sequencing ◽  
Information Needs ◽  
Market Demand ◽  
Next Generation ◽  
Clinical Integration ◽  
Public And Private ◽  
Regulatory Decision ◽  
Large Numbers ◽  
Next Generation Sequencing Ngs ◽  
Generation Sequencing

Clinical next generation sequencing (NGS) is a term that refers to a variety of technologies that permit rapid sequencing of large numbers of DNA segments, up to and including entire genomes. As an approach that is playing an increasingly important role in obtaining genetic information from patients, it may be viewed by public and private payers either positively, as an enabler of the promised benefits of personalized medicine, or as “the perfect storm” resulting from the confluence of high market demand, an uproven technology, and an unprepared delivery system. A number of recent studies have noted that coverage and reimbursement will be critical for clinical integration of NGS, yet the evidentiary pathway for payer decision-making is unclear. Although there are multiple reasons for this uncertain reimbursement environment, the situation stems in large part from a long-standing lack of alignment between the information needs of regulators and post-regulatory decision-makers such as payers.

scholarly journals The Clinical Utility of Next Generation Sequencing Results in a Community-Based Hereditary Cancer Risk Program

2016 ◽  
Vol 26 (1) ◽  
pp. 105-112 ◽  
Author(s):  
A. E. Bunnell ◽  
C. A. Garby ◽  
E. J. Pearson ◽  
S. A. Walker ◽  
L. E. Panos ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Cancer Risk ◽  
Hereditary Cancer ◽  
Clinical Utility ◽  
Next Generation ◽  
Community Based ◽  
Generation Sequencing

Abstract 4445: Defining a pipeline to use next generation sequencing for genetic testing in hereditary cancer

2012 ◽  
Author(s):  
Conxi Lazaro ◽  
Adriana López-Doriga ◽  
Ester Castellsagué ◽  
Jesús del Valle ◽  
Eva Tornero ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Next Generation Sequencing ◽  
Hereditary Cancer ◽  
Next Generation ◽  
Generation Sequencing

Consensus document on the implementation of next generation sequencing in the genetic diagnosis of hereditary cancer

2018 ◽  
Vol 151 (2) ◽  
pp. 80.e1-80.e10
Author(s):  
José Luis Soto ◽  
Ignacio Blanco ◽  
Orland Díez ◽  
Javier García Planells ◽  
Isabel Lorda ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Hereditary Cancer ◽  
Genetic Diagnosis ◽  
Next Generation ◽  
Consensus Document ◽  
Generation Sequencing

scholarly journals The Perils of Single‐Site Genetic Testing for Hereditary Cancer Syndromes in the Era of Next‐Generation Sequencing

2018 ◽  
Vol 23 (4) ◽  
pp. 393-396
Author(s):  
Nicole Casasanta ◽  
Elizabeth Stark ◽  
Allison McHenry ◽  
Tara Biagi ◽  
Rebecca Kaltman
Keyword(s):  
Genetic Testing ◽  
Next Generation Sequencing ◽  
Hereditary Cancer ◽  
Single Site ◽  
Next Generation ◽  
Hereditary Cancer Syndromes ◽  
Cancer Syndromes ◽  
Generation Sequencing

MG-107 Multiple pathogenic variants identified by next-generation sequencing hereditary cancer panel testing – a case report

2015 ◽  
Vol 52 (Suppl 2) ◽  
pp. A3.1-A3
Author(s):  
Christopher A Tan ◽  
Marina Rabideau ◽  
Stephanie Cohen ◽  
Shan Yang ◽  
Karen Vikstrom ◽  
...  
Keyword(s):  
Case Report ◽  
Next Generation Sequencing ◽  
Hereditary Cancer ◽  
Next Generation ◽  
Panel Testing ◽  
Pathogenic Variants ◽  
Generation Sequencing ◽  
Cancer Panel
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