Synthesis, Characterization for New Nanometric VO(II)–Thioacetanilide Complexes by, Spectral, Thermal, Molecular Computations and DNA Interaction Study Beside Promising Antitumor Activity

2019 ◽  
Vol 29 (5) ◽  
pp. 1606-1624 ◽  
Author(s):  
Fawaz Saad ◽  
Nashwa El-Metwaly ◽  
Abdalla M. Khedr
Keyword(s):  
Antitumor Activity ◽  
Dna Interaction ◽  
Interaction Study ◽  
Molecular Computations

Synthesis, characterization, in vitro cytotoxicity and DNA interaction study of phosphanegold(I) complexes with dithiocarbamate ligands

2017 ◽  
Vol 464 ◽  
pp. 37-48 ◽  
Author(s):  
Said S. Al-Jaroudi ◽  
Muhammad Altaf ◽  
Adam A. Seliman ◽  
Shipra Yadav ◽  
Farukh Arjmand ◽  
...  
Keyword(s):  
Dna Interaction ◽  
In Vitro Cytotoxicity ◽  
Interaction Study

Heteroleptic mononuclear compounds of ruthenium(ii): synthesis, structural analyses, in vitro antitumor activity and in vivo toxicity on zebrafish embryos

2016 ◽  
Vol 45 (47) ◽  
pp. 19127-19140 ◽  
Author(s):  
O. A. Lenis-Rojas ◽  
A. R. Fernandes ◽  
C. Roma-Rodrigues ◽  
P. V. Baptista ◽  
F. Marques ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Dna Interaction ◽  
Zebrafish Embryos ◽  
In Vivo Toxicity ◽  
Mononuclear Compounds

Cytotoxic properties, DNA-interaction and in vivo toxicity were evaluated in Ru(ii) compounds.

DNA interaction and photodynamic antitumor activity of transition metal mono-hydroxyl corrole

2019 ◽  
Vol 90 ◽  
pp. 103085 ◽  
Author(s):  
Yan-Mei Sun ◽  
Waseem Akram ◽  
Fan Cheng ◽  
Ze-Yu Liu ◽  
Yu-Hui Liao ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Transition Metal ◽  
Dna Interaction

Synthesis, photophysical characterization, CASSCF/CASPT2 calculations and CT-DNA interaction study of amino and azido benzazole analogues

2020 ◽  
Vol 297 ◽  
pp. 111938 ◽  
Author(s):  
Eduarda S. Gil ◽  
Cláudia B. da Silva ◽  
Pablo A. Nogara ◽  
Carolina H. da Silveira ◽  
João B.T. da Rocha ◽  
...  
Keyword(s):  
Dna Interaction ◽  
Interaction Study ◽  
Ct Dna ◽  
Caspt2 Calculations

scholarly journals Cyclopalladated Benzophenone Imines: Synthesis, Antitumor Activity, Cell Accumulation, DNA Interaction, and Cathepsin B Inhibition

2014 ◽  
Vol 33 (24) ◽  
pp. 7284-7292 ◽  
Author(s):  
Joan Albert ◽  
Jaume Granell ◽  
Romana Qadir ◽  
Josefina Quirante ◽  
Carme Calvis ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Cathepsin B ◽  
Dna Interaction ◽  
Cell Accumulation

Synthesis and Leukemia Cell Growth Inhibition of a Series of 1,3-Dithiazolylbenzene Derivatives

2004 ◽  
Vol 69 (7) ◽  
pp. 1491-1498 ◽  
Author(s):  
Irene M. Lagoja ◽  
Koen Nauwelaerts ◽  
Christine Bal-Mahieu ◽  
Michela Pasqualini ◽  
Christian Bailly ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Antitumor Activity ◽  
Rna Viruses ◽  
Leukemia Cell ◽  
Dna Interaction ◽  
Benzene Derivatives ◽  
Cell Growth Inhibition ◽  
Dna And Rna ◽  
Hiv 1 ◽  
Potential Antitumor

By a slightly modified Hantzsch thiazole synthesis either 1,3-bis[(thiazol-2-yl)amino]benzene derivatives 2 or 1,3-bis[2-iminothiazol-3(2H)-yl]benzene derivatives 3 were exclusively obtained. The compounds can be distinguished by NMR spectroscopy. Compounds 2a-2d and 3a-3d were evaluated for their potential antitumor activity, DNA interaction, and for their activity against DNA and RNA viruses and against HIV-1 and HIV-2.

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