Attenuation of oxidative stress, inflammation and early markers of tumor promotion by caffeic acid in Fe-NTA exposed kidneys of Wistar rats

2011 ◽  
Vol 357 (1-2) ◽  
pp. 115-124 ◽  
Author(s):  
Muneeb U. Rehman ◽  
Sarwat Sultana
Keyword(s):  
Oxidative Stress ◽  
Caffeic Acid ◽  
Wistar Rats ◽  
Tumor Promotion ◽  
Early Markers

scholarly journals Amelioration of 1,2 Dimethylhydrazine (DMH) Induced Colon Oxidative Stress, Inflammation and Tumor Promotion Response by Tannic Acid in Wistar Rats

2012 ◽  
Vol 13 (9) ◽  
pp. 4393-4402 ◽  
Author(s):  
Oday O. Hamiza ◽  
Muneeb U. Rehman ◽  
Mir Tahir ◽  
Rehan Khan ◽  
Abdul Quaiyoom Khan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Tannic Acid ◽  
Wistar Rats ◽  
Tumor Promotion

scholarly journals IN VIVO HEPATOPROTECTIVE EFFECT OF CAFFEIC ACID ON MERCURIC CHLORIDE-INDUCED BIOCHEMICAL CHANGES IN ALBINO WISTAR RATS

2019 ◽  
pp. 119-124
Author(s):  
MANOGARAN MANJU ◽  
GANESAN JAGASEESAN
Keyword(s):  
Oxidative Stress ◽  
Body Weight ◽  
Caffeic Acid ◽  
Liver Tissue ◽  
Wistar Rats ◽  
Control Level ◽  
Antioxidant Properties ◽  
Sublethal Dose ◽  
Mercury Chloride

Objective: Mercury (Hg) is a highly dangerous and also one of the harmful heavy metals which induces oxidative stress in the animal body. The present study is planned to examine the possible defensive result of caffeic acid (CA) against mercury chloride (HgCl2)-induced hepatotoxicity in male albino Wistar rats, Rattus norvegicus. Methods: Sublethal dose of HgCl2 (1.29 mg/kg body weight) was administrated in rats for 15 days through oral dose and the CA was administrated for another 15 days on mercuric-intoxicated rats. After completing the scheduled exposure time, the rats were sacrificed and the whole liver organ was removed immediately from the animal, and it was used to carry out for biochemical and bioenzymological studies to observe. Results: The level of lipid peroxidation (LPO) content reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in the liver tissue. CA is an energetic component in the phenolic propolis extract and also in a wide variety of plants, and a strong antioxidant helps to prevent oxidative damage and to reduce oxidative stress. The antioxidants such as GPx, CAT, and SOD and non-antioxidant GSH were significantly decreased, and also, the LPO level was increased in mercury toxicity rats. The treatment of CA (5 mg/kg body weight) in the liver tissue shows considerable declining in the level of oxidant content and along with an increase in the level of antioxidant properties by the way of improvement in liver tissues. Antioxidant and non-antioxidant enzyme (LOP, GSH, GPx, SOD, and CAT) activities were also significantly decreased to near untreated control level when compared to Hg-treated group. The CA acid alone treatment showed the enhanced antioxidant levels and not any alteration in the levels of biochemical parameters when compared with control. Conclusion: These observations of the present experimental study clearly explained the detoxify effects and protective effect of CA against HgCl2 toxicity in liver tissue.

Effects of Chronic Exposure to Electromagnetic Waves at 930 MHz Frequency on Oxidative Stress in Plasma and Some Organs of Wistar Rats

2012 ◽  
Vol 3 (7) ◽  
pp. 1-7
Author(s):  
L. TAZROUT L. TAZROUT ◽  
◽  
K. TALEA K. TALEA ◽  
S. EL AMRANI S. EL AMRANI ◽  
I. M’TOUGUY I. M’TOUGUY ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Chronic Exposure ◽  
Electromagnetic Waves ◽  
Wistar Rats

Thymus Vulgaris Inhibit Lung Fibrosis Progression and Oxidative Stress Induced by Bleomycin in Wistar Rats

2021 ◽  
pp. 1-11
Author(s):  
Sana Bahri ◽  
Mona Mlika ◽  
Afef Nahdi ◽  
Ridha Ben Ali ◽  
Saloua Jameleddine
Keyword(s):  
Oxidative Stress ◽  
Lung Fibrosis ◽  
Wistar Rats ◽  
Thymus Vulgaris ◽  
Fibrosis Progression ◽  
And Oxidative Stress
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