The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats

2021 ◽  
Author(s):  
Ghadha Ibrahim Fouad ◽  
Mohamed R. Mousa
Keyword(s):  
Pulmonary Fibrosis ◽  
Lipoic Acid ◽  
Hepatic Injury ◽  
Alpha Lipoic Acid ◽  
Protective Potential

scholarly journals Alpha-Lipoic Acid and N-Acetyl Cysteine Ameliorates Oxidative Stress and Hepatic Injury in Alloxan-Induced Diabetic Rabbits

2012 ◽  
Vol 1 (1) ◽  
pp. 7-17 ◽  
Author(s):  
Omar H M ◽  
Saad El-dien H. M. ◽  
Saeed M A ◽  
Al-Salahy M. B. ◽  
Abel-Tawab H. S.
Keyword(s):  
Oxidative Stress ◽  
Lipoic Acid ◽  
Hepatic Injury ◽  
Alpha Lipoic Acid ◽  
Acetyl Cysteine ◽  
Diabetic Rabbits

Influence of alpha lipoic acid on antioxidant status in D-galactosamine-induced hepatic injury

2008 ◽  
Vol 24 (10) ◽  
pp. 635-642 ◽  
Author(s):  
TS Shanmugarajan ◽  
D Sivaraman ◽  
I Somasundaram ◽  
M Arunsundar ◽  
E Krishnakumar ◽  
...  
Keyword(s):  
Liver Injury ◽  
Lipoic Acid ◽  
Hepatic Injury ◽  
Serum Marker ◽  
Alpha Lipoic Acid ◽  
Suitable Candidate ◽  
Single Intraperitoneal Injection ◽  
Cellular Abnormalities ◽  
Enzymic Antioxidants ◽  
And Oxidative Stress

D-Galactosamine (GalN)-induced liver injury is associated with reactive oxygen species and oxidative stress. In the present study, we evaluated the effect of alpha lipoic acid (ALA) supplementation on acute GalN-induced oxidative liver injury. Hepatotoxicity induced by single intraperitoneal injection of GalN (500 mg/kg body wt) was evident from increase in lipid peroxidation and serum marker enzymes (asparate transaminase, alanine transaminase, alkaline phosphatase, and lactate dehydrogenase). The decreased activities of enzymic antioxidants (superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase) as well as glutathione levels were the salient features observed in GalN-induced hepatotoxicity. Pretreatment with ALA (50 mg/kg body weight for 7 days) significantly precluded these changes and prevents the hepatic injury. Hence, this study clearly exemplified that ALA might be a suitable candidate against GalN-induced cellular abnormalities.

Effect of the alpha-lipoic acid on apoptosis in HIT-T15 cells induced by high glucose

2010 ◽  
Vol 34 (8) ◽  
pp. S14-S14
Author(s):  
Yi Yang ◽  
Wei‑Ping Wang ◽  
Yi‑Nan Liu ◽  
Ting Guo ◽  
Ping Chen ◽  
...  
Keyword(s):  
Lipoic Acid ◽  
High Glucose ◽  
Alpha Lipoic Acid

Evaluation of dissolution profiles of alpha lipoic acid soft gelatin capsules and tablets

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
A Uzunovic ◽  
S Hadzidedic ◽  
A Elezovic ◽  
S Pilipovic ◽  
A Sapcanin
Keyword(s):  
Lipoic Acid ◽  
Alpha Lipoic Acid ◽  
Gelatin Capsules ◽  
Soft Gelatin Capsules

Secunder prevention with alpha-lipoic acid and vitamin E in porphyria cutanea tarda patients

2008 ◽  
Vol 46 (05) ◽  
Author(s):  
E Székely ◽  
K Szentmihályi ◽  
M Bor ◽  
Á Pusztai ◽  
T Kurucz ◽  
...  
Keyword(s):  
Vitamin E ◽  
Lipoic Acid ◽  
Porphyria Cutanea Tarda ◽  
Alpha Lipoic Acid

Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells

Diabetes ◽  
1997 ◽  
Vol 46 (9) ◽  
pp. 1481-1490 ◽  
Author(s):  
A. Bierhaus ◽  
S. Chevion ◽  
M. Chevion ◽  
M. Hofmann ◽  
P. Quehenberger ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Lipoic Acid ◽  
Alpha Lipoic Acid ◽  
Advanced Glycation ◽  
Advanced Glycation End Product ◽  
Cultured Endothelial Cells ◽  
Nf Kappab

The use of rosuvastatin and alpha lipoic acid in patients with unstable angina

2017 ◽  
Vol 23 (1-2) ◽  
pp. 9-14
Author(s):  
E.H. Zaremba ◽  
◽  
O.V. Smalyukh ◽  
O.V. Zaremba-Fedchyshyn ◽  
O.V. Zaremba ◽  
...  
Keyword(s):  
Unstable Angina ◽  
Lipoic Acid ◽  
Alpha Lipoic Acid
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