Camphor nitroimine: a key building block in unusual transformations and its applications in the synthesis of bioactive compounds

Author(s):  
Emerson Teixeira da Silva ◽  
Luciano da Silva Santos ◽  
Gabriel Fernandes de Andrade ◽  
Emerson Joaquim Rodrigues Rosa ◽  
Marcus Vinícius Nora de Souza
2020 ◽  
Vol 24 (6) ◽  
pp. 583-621
Author(s):  
Arvind Singh ◽  
Gurpreet Kaur ◽  
Bubun Banerjee

Bis(indolyl)methane skeleton is the main building block of many naturally occurring bioactive compounds. Bis(indolyl)methanes are found to possess a wide range of pharmaceuitical efficacies. These important scaffolds are being used as anti-cancer, antioxidant, anti-bacterial, anti-inflammatory, and anti-proliferative agents. In this review, we summarized the latest developments on the synthesis of various bis/tris(indolyl)methane derivatives from the reactions of two equivalents of indoles and one equivalent of aldehydes or indole-3-carbaldehydes under various reaction conditions. More than hundred different catalysts were employed for these transformations which include various metal catalysts, ionic liquids, organocatalysts, surfactants, homogeneous, heterogeneous catalysts etc.


2017 ◽  
Vol 20 (4) ◽  
pp. 346-358 ◽  
Author(s):  
Mohamed Aissou ◽  
Zoubida Chemat-Djenni ◽  
Edinson Yara-Varón ◽  
Anne-Sylvie Fabiano-Tixier ◽  
Farid Chemat

Author(s):  
jie li ◽  
Jaiqi Yao ◽  
Dong Zou ◽  
Lingfeng Chen ◽  
Patrick Walsh ◽  
...  

The imide moiety is a well-known structural motif in bioactive compounds and a useful building block in a variety of processes. Using N-acylglutarimides with MN(SiMe3)2 and either N-acylpyrroles or aryl...


Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
B Biloa Messi ◽  
R Ho ◽  
A Meli Lannang ◽  
JG Tangmouo ◽  
A Marston ◽  
...  
Keyword(s):  

Planta Medica ◽  
2012 ◽  
Vol 78 (05) ◽  
Author(s):  
L Bohlin ◽  
C Alsmark ◽  
U Göransson ◽  
M Klum ◽  
C Wedén ◽  
...  
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document