Silver nanoparticles delivery system based on natural rubber latex membranes

Natural rubber latex (NRL) fromHevea brasiliensisis easily manipulated, low cost, is of can stimulate natural angiogenesis and cellular adhesion, is a biocompatible, material and presents high mechanical resistance. Ciprofloxacin (CIP) is a synthetic antibiotic (fluoroquinolone) used in the treatment of infection at external fixation screws sites and remote infections, and this use is increasingly frequent in medical practice. The aim of this study was to develop a novel sustained delivery system for CIP based on NRL membranes and to study its delivery system behavior. CIP was found to be adsorbed on the NRL membrane, according to results of energy dispersive X-ray spectroscopy. Results show that the membrane can release CIP for up to 59.08% in 312 hours and the mechanism is due to super case II (non-Fickian). The kinetics of the drug release could be fitted with double exponential function X-ray diffraction and Fourier transform infrared (FTIR) spectroscopy shows some interaction by hydrogen bound, which influences its mechanical behavior.

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Effects of silver nanoparticles on physical and antibacterial properties of natural rubber latex foam

Materials Today Proceedings ◽

10.1016/j.matpr.2019.06.230 ◽

2019 ◽

Vol 17 ◽

pp. 1914-1920 ◽

Cited By ~ 1

Author(s):

Khemara Mam ◽

Rapeephun Dangtungee

Keyword(s):

Silver Nanoparticles ◽

Natural Rubber ◽

Natural Rubber Latex ◽

Antibacterial Properties ◽

Rubber Latex

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The Role of Ammonia in Synthesis of Silver Nanoparticles in Skim Natural Rubber Latex

Journal of Nanoscience ◽

10.1155/2016/7258313 ◽

2016 ◽

Vol 2016 ◽

pp. 1-6 ◽

Cited By ~ 3

Author(s):

Panu Danwanichakul ◽

Thanawat Suwatthanarak ◽

Chidchanok Suwanvisith ◽

Duangkamol Danwanichakul

Keyword(s):

Silver Nanoparticles ◽

Natural Rubber ◽

Natural Rubber Latex ◽

Ammonia Concentration ◽

Rubber Latex ◽

Controlling Effect ◽

Uv Visible ◽

Size Controlling ◽

Latex Production

Silver nanoparticles (AgNPs) were synthesized in skim natural rubber latex, the by-product from concentrated latex production. The role of ammonia was investigated by varying the concentration to be 0.217, 0.362, 0.377, 0.392, and 0.406 wt%. The emergence of AgNPs was detected by UV-visible spectrophotometer and electrical conductivity meter. Upon increasing ammonia concentration, the ABS peak increased to a maximum and slightly shifted to a higher wavelength and then it decreased afterward and slightly shifted to a lower wavelength. The shift of the ABS peak was consistent with the conductivity result. The kinetic model was proposed to explain the competition between the reducing effect and size-controlling effect of ammonia. The reducing effect seemed to dominate in the low range of concentration while the size-controlling effect via the formation of AgNH32+ complex ion was important in the higher range. The TEM figures evidently confirmed the effects.

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