scholarly journals Glycyl-l-Glutamine Disposition in Rat Choroid Plexus Epithelial Cells in Primary Culture: Role of PEPT2

2005 ◽  
Vol 22 (8) ◽  
pp. 1281-1286 ◽  
Author(s):  
Yongjun Hu ◽  
Scott M. Ocheltree ◽  
Jianming Xiang ◽  
Richard F. Keep ◽  
David E. Smith
Keyword(s):  
Epithelial Cells ◽  
Primary Culture ◽  
Choroid Plexus ◽  
Choroid Plexus Epithelial

scholarly journals Characterization of folate uptake by choroid plexus epithelial cells in a rat primary culture model

2007 ◽  
Vol 104 (6) ◽  
pp. 1494-1503 ◽  
Author(s):  
Jan B. Wollack ◽  
Benedette Makori ◽  
Stuti Ahlawat ◽  
Rajeth Koneru ◽  
Sonia C. Picinich ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Primary Culture ◽  
Choroid Plexus ◽  
Culture Model ◽  
Choroid Plexus Epithelial

scholarly journals Neural differentiation of choroid plexus epithelial cells: role of human traumatic cerebrospinal fluid

2017 ◽  
Vol 12 (1) ◽  
pp. 84 ◽  
Author(s):  
Yousef Sadeghi ◽  
Elham Hashemi ◽  
Abbas Aliaghaei ◽  
Afsoun Seddighi ◽  
Abbas Piryaei ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Epithelial Cells ◽  
Choroid Plexus ◽  
Neural Differentiation ◽  
Choroid Plexus Epithelial

scholarly journals Porcine Choroid Plexus Epithelial Cells Induce Streptococcus suis Bacteriostasis In Vitro

2004 ◽  
Vol 72 (5) ◽  
pp. 3084-3087 ◽  
Author(s):  
Rüdiger A. Adam ◽  
Tobias Tenenbaum ◽  
Peter Valentin-Weigand ◽  
Maurice Laryea ◽  
Bernd Schwahn ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Bacterial Meningitis ◽  
Choroid Plexus ◽  
Host Defense ◽  
Streptococcus Suis ◽  
Active Role ◽  
Necrosis Factor Alpha ◽  
Ifn Γ ◽  
Choroid Plexus Epithelial

ABSTRACT The involvement of the choroid plexus in host defense during bacterial meningitis is unclear. Aiming to elucidate possible antibacterial mechanisms, we stimulated primary porcine choroid plexus epithelial cells (pCPEC) with proinflammatory cytokines and challenged them with various Streptococcus suis strains. In the supernatant of gamma interferon (IFN-γ)-stimulated pCPEC, streptococcal growth was markedly suppressed. Costimulation with tumor necrosis factor alpha enhanced this bacteriostatic effect, while supplementation of l-tryptophan completely eliminated it. We also demonstrate that an activation of indoleamine 2,3-dioxygenase in the pCPEC seems to be responsible for the IFN-γ-induced bacteriostasis. This supports the hypothesis of an active role of the choroid plexus in host defense against bacterial meningitis.

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