Quality of life after dislocation of hip arthroplasty: a prospective cohort study on 319 patients with femoral neck fractures with a one-year follow-up

IntroductionSurvivors of acute pancreatitis (AP) have shorter overall survival and increased incidence of new-onset cardiovascular, respiratory, liver and renal disease, diabetes mellitus and cancer compared with the general population, but the mechanisms that explain this are yet to be elucidated. Our aim is to characterise the precise nature and extent of organ dysfunction following an episode of AP.Methods and analysisThis is an observational prospective cohort study in a single centre comprising a University hospital with an acute and emergency receiving unit and clinical research facility. Participants will be adult patient admitted with AP. Participants will undergo assessment at recruitment, 3 months and 3 years. At each time point, multiple biochemical and/or physiological assessments to measure cardiovascular, respiratory, liver, renal and cognitive function, diabetes mellitus and quality of life. Recruitment was from 30 November 2017 to 31 May 2020; last follow-up measurements is due on 31 May 2023. The primary outcome measure is the incidence of new-onset type 3c diabetes mellitus during follow-up. Secondary outcome measures include: quality of life analyses (SF-36, Gastrointestinal Quality of Life Index); montreal cognitive assessment; organ system physiological performance; multiomics predictors of AP severity, detection of premature cellular senescence. In a nested cohort within the main cohort, individuals may also consent to multiparameter MRI scan, echocardiography, pulmonary function testing, cardiopulmonary exercise testing and pulse-wave analysis.Ethics and disseminationThis study has received the following approvals: UK IRAS Number 178615; South-east Scotland Research Ethics Committee number 16/SS/0065. Results will be made available to AP survivors, caregivers, funders and other researchers. Publications will be open-access.Trial registration numbersClinicalTrials.gov Registry (NCT03342716) and ISRCTN50581876; Pre-results.

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Quality of life one year post-Shiga toxin-producingEscherichia coliO104 infection - A prospective cohort study

Neurogastroenterology & Motility ◽

10.1111/nmo.12503 ◽

2015 ◽

Vol 27 (3) ◽

pp. 370-378 ◽

Cited By ~ 4

Author(s):

B. Riegel ◽

W. Broicher ◽

K. Wegscheider ◽

V. Andresen ◽

E. Brähler ◽

...

Keyword(s):

Quality Of Life ◽

Cohort Study ◽

Prospective Cohort Study ◽

Shiga Toxin ◽

Prospective Cohort ◽

One Year

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The Influence of Leg Length Discrepancy after Total Hip Arthroplasty on Function and Quality of Life: A Prospective Cohort Study

The Journal of Arthroplasty ◽

10.1016/j.arth.2015.04.012 ◽

2015 ◽

Vol 30 (9) ◽

pp. 1638-1642 ◽

Cited By ~ 31

Author(s):

Sarwar S. Mahmood ◽

Sebastian S. Mukka ◽

Sead Crnalic ◽

Arkan S. Sayed-Noor

Keyword(s):

Quality Of Life ◽

Cohort Study ◽

Total Hip Arthroplasty ◽

Prospective Cohort Study ◽

Hip Arthroplasty ◽

Prospective Cohort ◽

Leg Length Discrepancy ◽

Leg Length ◽

Length Discrepancy

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Protocol for a prospective cohort study of open tibia fractures in Malawi with a nested implementation of open fracture guidelines

Wellcome Open Research ◽

10.12688/wellcomeopenres.17145.1 ◽

2021 ◽

Vol 6 ◽

pp. 228

Author(s):

Alexander Thomas Schade ◽

Nohakhelha Nyamulani ◽

Leonard Ngoe Banza ◽

Andrew John Metcalfe ◽

Andrew Leather ◽

...

Keyword(s):

Quality Of Life ◽

Cohort Study ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Open Fracture ◽

Open Fractures ◽

Fracture Management ◽

Tibia Fractures ◽

One Year

Background: Road traffic injury (RTI) is the largest cause of death amongst 15–39-year-old people worldwide, and the burden of injuries such as open tibia fractures are rapidly increasing in Malawi. This study aims to investigate disability and economic outcomes of people with open tibia fractures in Malawi and improve these with locally delivered implementation of open fracture guidelines. Methods: This is a prospective cohort study describing function, quality of life and economic burden of open tibia fractures in Malawi. In total, 160 participants will be recruited across six centres and will be followed-up with face-to-face interviews at six weeks, three months, six months and one year following injury. The primary outcome will be function at one year measured by the short musculoskeletal functional assessment (SMFA) score. Secondary outcomes will include quality of life measured by EuroQol EQ-5D-3L, catastrophic loss of income and implementation outcomes (acceptability, adoption, appropriateness, costs, feasibility, fidelity, penetration, and sustainability) at one year. A nested pilot pre-post implementation study of an interventional bundle for all open fractures will be developed based on other implementation studies from low- and middle-income countries (LMICs). Regression analysis will be used to model and investigate associations between SMFA score and fracture severity, infection and the pre- and post-training course period. Outcome: This prospective cohort study will report patient reported outcomes from open tibia fractures in low-resource settings. Subsequent detailed evaluation of both the clinical and implementation components of the study will promote sustainability of improved open fractures management in the study sites and further scale-up of open fracture management guidelines. Ethics: Ethics approval has been obtained from the Liverpool School of Tropical Medicine and College of Medicine Research and Ethics committee.

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Does one year change in quality of life predict the mortality in patients with chronic obstructive pulmonary disease?—Prospective cohort study

Journal of Thoracic Disease ◽

10.21037/jtd.2019.07.89 ◽

2019 ◽

Vol 11 (8) ◽

pp. 3626-3632 ◽

Cited By ~ 2

Author(s):

Yavuz Havlucu ◽

Arzu Yorgancıoglu ◽

Aysin Sakar Coskun ◽

Pinar Celık

Keyword(s):

Quality Of Life ◽

Chronic Obstructive Pulmonary Disease ◽

Cohort Study ◽

Pulmonary Disease ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Chronic Obstructive ◽

Obstructive Pulmonary Disease ◽

One Year

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Re: Quality of Life in Patients with Non-Muscle-Invasive Bladder Cancer: One-Year Results of a Multicentre Prospective Cohort Study

The Journal of Urology ◽

10.1016/j.juro.2016.07.051 ◽

2016 ◽

Vol 196 (4) ◽

pp. 1045-1046

Author(s):

Sam S. Chang

Keyword(s):

Quality Of Life ◽

Bladder Cancer ◽

Cohort Study ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Invasive Bladder Cancer ◽

Muscle Invasive Bladder Cancer ◽

Muscle Invasive ◽

One Year

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Neurological complications of breast cancer: study protocol of a prospective cohort study

BMJ Open ◽

10.1136/bmjopen-2014-006301 ◽

2014 ◽

Vol 4 (10) ◽

pp. e006301 ◽

Cited By ~ 17

Author(s):

Susana Pereira ◽

Filipa Fontes ◽

Teresa Sonin ◽

Teresa Dias ◽

Maria Fragoso ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Neuropathic Pain ◽

Cohort Study ◽

Peripheral Neuropathy ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Neurological Complications

IntroductionThe improvement in breast cancer survival rates, along with the expected overdiagnosis and overtreatment associated with breast cancer screening, requires a comprehensive assessment of its burden. Neurological complications can have a devastating impact on these patients; neuropathic pain and chemotherapy-induced peripheral neuropathy are among the most frequently reported. This project aims to understand the burden of neurological complications of breast cancer treatment in Northern Portugal, and their role as mediator of the impact of the treatment in different dimensions of the patients’ quality of life.Methods and analysisA prospective cohort study was designed to include 500 patients with breast cancer, to be followed for 3 years. The patients were recruited at the Portuguese Oncology Institute of Porto and evaluations were planned at different stages: pretreatment, after surgery, after chemotherapy (whenever applicable) and at 1 and 3 years after enrolment. Patients diagnosed with neuropathic pain or chemotherapy-induced peripheral neuropathy (subcohorts), were also evaluated at the moment of confirmation of clinical diagnosis of the neurological complication and 6 months later. In each of the follow-up periods, a neurological examination has been performed by a neurologist. Data were collected on sociodemographic and clinical characteristics, quality of life, sleep quality, and anxiety and depression. Between January and December 2012, we recruited and conducted the baseline evaluation of 506 participants. The end of the follow-up period is scheduled for December 2015.Ethics and disseminationThe study protocol was approved by the Ethics Committee of the Portuguese Oncology Institute of Porto and all patients provided written informed consent. All study procedures were developed in order to assure data protection and confidentiality. Results from this project will be disseminated in international peer-reviewed journals and presented in relevant conferences.

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Comparison of Life Quality in Patients Undergoing Open Vein Harvesting and Endoscopic Vein Harvesting Techniques: A Prospective Cohort Study

Shiraz E-Medical Journal ◽

10.5812/semj.102169 ◽

2020 ◽

Vol In Press (In Press) ◽

Author(s):

Ahmad Amouzeshi ◽

Bibi Fatemeh Shakhsemampour ◽

Somaye Jomefourjan ◽

Reyhaneh Panahi ◽

Zahra Amouzeshi

Keyword(s):

Quality Of Life ◽

Cohort Study ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Life Quality ◽

Sufficient Information ◽

Endoscopic Vein Harvesting ◽

Vein Harvesting

Background: As the traditional indicators of the operative outcomes, including morbidity and mortality, cannot give sufficient information on a patient’s physical, mental, emotional, and functional well-being alone, we aimed to compare life quality in the patients under open vein harvesting (OVH) and endoscopic vein harvesting (EVH) techniques after four years of follow-up. Methods: This prospective cohort study followed all the patients who were scheduled for off-pump CABG in the Mashhad-based Imam Reza Hospital, in October 2013, for 4 years. Accordingly, data related to their quality of life were collected, and their life quality was then compared using the WHOQOL-BREF scale. T-test and relative risk were also used. Results: This study was conducted on a total of 103 patients under the two techniques of OVH (n = 53) and EVH (n = 50). The difference between the EVH (4.7%) and OVH (16.3%) groups at the demographic characteristics was the Transient Ischemic Attack (P = 0.023). After a 4-years follow-up period, no significant differences were observed between the patients undergoing the two techniques of OVH and EVH in all the domains of life quality. Conclusions: According to the obtained results, there was no difference in the quality of life between the patients undergoing OVH and EVH techniques over a four-year period. In this regard, further investigations are recommended on the quality of life in patients under the two techniques of OVH and EVH with long-term follow-up periods.

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