Enhancement strategies of bioactive compound production in adventitious root cultures of Eleutherococcus koreanum Nakai subjected to methyl jasmonate and salicylic acid elicitation through airlift bioreactors

2014 ◽  
Vol 120 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Eun Jung Lee ◽  
So Young Park ◽  
Kee Yoeup Paek
Keyword(s):  
Salicylic Acid ◽  
Methyl Jasmonate ◽  
Adventitious Root ◽  
Bioactive Compound ◽  
Root Cultures ◽  
Adventitious Root Cultures ◽  
Airlift Bioreactors

scholarly journals Enhanced Aryltetralin Lignans Production in Linum Adventi-Tious Root Cultures

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5189
Author(s):  
Michela Alfieri ◽  
Iride Mascheretti ◽  
Roméo A. Dougué Kentsop ◽  
Roberto Consonni ◽  
Franca Locatelli ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Plant Defense ◽  
Methyl Jasmonate ◽  
Human Health ◽  
Adventitious Root ◽  
Root Cultures ◽  
Adventitious Root Cultures ◽  
First Time ◽  
Defense Molecules

Lignans are the main secondary metabolites synthetized by Linum species as plant defense molecules. They are also valuable for human health, in particular, for their potent antiviral and antineoplastic properties. In this study, the adventitious root cultures of three Linum species (L. flavum, L. mucronatum and L. dolomiticum) were developed to produce aryltetralin lignans. The effect of two elicitors, methyl jasmonate and coronatine, on aryltetralin lignans production was also evaluated. The adventitious root cultures from L. dolomiticum were obtained and analyzed for the first time and resulted as the best producer for all the aryltetralins highlighted in this system: Podophyllotoxin, 6-methoxypodophyllotoxin and 6-methoxypodophyllotoxin-7-O-β-glucoside, the last showing a productivity of 92.6 mg/g DW. The two elicitors differently affected the production of the 6-methoxypodophyllotoxin and 6-methoxypodophyllotoxin-7-O-β-glucoside.

scholarly journals Curcubinoyl-conjugated flavonoids from methyl jasmonate-treated wild ginseng adventitious root cultures

2021 ◽  
Author(s):  
Qing Liu ◽  
Seon Beom Kim ◽  
Yang Hee Jo ◽  
Jong Hoon Ahn ◽  
Ayman Turk ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Methyl Jasmonate ◽  
Adventitious Root ◽  
Efficient Production ◽  
Root Cultures ◽  
Raw 264.7 Macrophages ◽  
Adventitious Root Cultures ◽  
Chemical Structures ◽  
Wild Ginseng ◽  
New Metabolites

Abstract Wild ginseng (Panax ginseng) adventitious root cultures were prepared by elicitation using methyl jasmonate and investigated further to find new secondary metabolites. Chromatographic fractionation of wild ginseng adventitious root cultures led to the isolation of eleven compounds. The chemical structures of isolated compounds were identified as four known flavanone derivatives (1–4), one new curcubinoyl derivative, jasmogin A (5) and six new curcubinoyl-flavanone conjugates, jasmoflagins A-F (6–11) by extensive spectroscopic analysis. Newly isolated curcubinoyl derivatives showed inhibitory activity against lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 macrophages. Curcubinoyl moiety is structurally similar with methyl jasmonate, which was used as an elicitor. Therefore, our present study suggested that elicitor might increase the content of active constituents and also contribute to the production of new metabolites by participation as precursors in biosynthesis. Taken together, plant cell cultures are useful not only for efficient production of active compounds but also development of new secondary metabolites.

Sign in / Sign up

Export Citation Format

Share Document