The relationship between sleep disorders, anxiety, depression, and cognitive function with restless legs syndrome (RLS) in the elderly

Author(s):  
Yuan Xu ◽  
Hongbin Wen ◽  
Jie Li ◽  
Jing Yang ◽  
Kai Luo ◽  
...  
2013 ◽  
Vol 20 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Eun Soo Kim ◽  
In-Young Yoon ◽  
Kukju Kweon ◽  
Hye Youn Park ◽  
Chung Suk Lee ◽  
...  

2008 ◽  
Vol 6 (2) ◽  
pp. 102-109 ◽  
Author(s):  
Satoru HARANO ◽  
Takashi OHIDA ◽  
Yoshitaka KANEITA ◽  
Eise YOKOYAMA ◽  
Tetsuo TAMAKI ◽  
...  

2019 ◽  
Vol 21 (4) ◽  
pp. 157-165 ◽  
Author(s):  
Edgar Carnero Contentti ◽  
Pablo A. López ◽  
Debora Nadur ◽  
María Eugenia Balbuena ◽  
Ana Mariel Finkelstein ◽  
...  

Abstract Background: Restless legs syndrome (RLS) frequency, and its association with depression, anxiety, sleep disorders, and fatigue, has not been previously studied in Latin American patients with multiple sclerosis (MS). We aimed to assess RLS frequency in patients with MS living in Argentina and to examine potential associations with depression, anxiety, and sleep disorders. Methods: A cross-sectional study (n = 427) was conducted using a self-administered questionnaire, including International RLS Study Group criteria, to compare RLS frequency in patients with MS versus controls. The Hospital Anxiety and Depression Scale and the Fatigue Severity Scale were administered to all participants. Insomnia, excessive daytime somnolence, and other risk factors in patients with MS with RLS were analyzed using logistic regression. Results: We included 189 patients with definite MS and 238 controls. The RLS frequency was 29.1% in patients with MS versus 13.0% in controls (odds ratio [OR] = 2.74, P = .00005). Moreover, clinically significant RLS (csRLS; ie, symptoms present ≥2 days per week) frequency was 19.4% in patients with MS versus 4.2% in controls (OR = 5.37, P < .00001). Longer MS duration and presence of anxiety, depression, insomnia, and smoking cigarettes were all significantly associated with RLS. Multivariate analysis showed that anxiety and fatigue were significantly associated with MS with RLS and MS with csRLS. Conclusions: Both RLS and csRLS showed strong association with MS, supporting the need to screen for anxiety/depression, sleep quality, and fatigue in this patient population. We believe that identifying the presence and severity of these conditions would contribute to better MS management and treatment.


2020 ◽  
Author(s):  
Jia-Ming Chen ◽  
Ping-Fang Chiu ◽  
Yu-Jun Chang ◽  
Po-Chi Hsu ◽  
Chia-Chu Chang ◽  
...  

Abstract Background The aim of the present study was to evaluate the effects of electroacupuncture (EA) in hemodialysis patients with restless leg syndrome (RLS) by heart rate variability (HRV) monitor. Methods112 subjects who were hemodialysis patients with RLS will be divided into 2 groups: experimental and control. Each subject will receive the treatment relevant to their group 2 times a week for 4 weeks. After 4 weeks of treatment the subject will enter a 2-week washout period, after which the subjects will switch groups. Measurements will include HRV recordings, International Restless Legs Syndrome Rating Scale (IRLSRS) and Insomnia Severity Index (ISI). DiscussionThis study is the first investigation to analyze the relationship between EA and the change of HRV by an objective monitor. If the findings of the current trial are positive, this study will also help support an effective, safe and cheap approach to clinical treatment of this challenging disorder, help foster improved understanding the relationship between RLS and HRV, and ultimately contribute to elucidate the mechanisms of EA. Trial registrationClinicalTrials.gov Identifier: NCT04356794; registration date: April 22, 2020.


1993 ◽  
Vol 69 (815) ◽  
pp. 701-703 ◽  
Author(s):  
S. T. O'Keeffe ◽  
J. Noel ◽  
J. N. Lavan

2007 ◽  
Vol 22 (4) ◽  
pp. 589-589
Author(s):  
Franco Gemignani ◽  
Francesca Brindani

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