Human health risk from organ-specific accumulation of toxic metals and response of antioxidants in edible fish species from Chenab River, Pakistan

2013 ◽  
Vol 21 (6) ◽  
pp. 4409-4417 ◽  
Author(s):  
Sidra Waheed ◽  
Atif Kamal ◽  
Riffat Naseem Malik
2020 ◽  
Author(s):  
Zeshan Shah ◽  
Zubair Nengroo

Abstract Study was carried out to determine the concentration and bioaccumulation of pesticide residues in edible fish from river Ganga, India, to assess human health risk via consumption of fish. Two commonly edible fish species bagrid catfish and common carp were collected. The n-hexane extract of the muscle tissues were characterized by gas chromatography coupled to mass spectrometry and quantified by electron capture detector for pesticide residues. Bioaccumulation factors (BAFs) in common carp of pesticides were found to be higher than those in bagrid fish. Daily exposures of pesticides for consumers via fish consumption were determined by calculating and comparing estimated daily intake (EDI) with ADI values. The EDI results in our study were insignificantly high from ADI values. Non-carcinogenic and carcinogenic risks were evaluated by Target hazard quotient (THQ) and risk ratio (R), respectively. Hazard quotients (THQ) were found to be lower than the set 1.0, inferring non-carcinogenic risk by consumption of fish from the river. Regard to contaminants carcinogenic affects the total risk ratio (R) value of pesticides were found lower than threshold of tolerable risk except of heptachlor indicating carcinogenic risk via consumption of fish. The results demonstrate that due to increased pollution in the ecosystem required more attention.


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